Gene name: WDR5
Protein name: WD repeat-containing protein
List of molecules and drugs that interact with protein P61964
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P61964_0BW | 0BW | n/a | 6457069 | CHEMBL3906778 | methyl 3-[(3-methoxybenzoyl)amino]-4-(4-methylpiperazin-1-yl)benzoate | n/a | |
| 2 | P61964_2MR | 2MR | DB02302 | 169148;51351707; | n/a | N3, N4-DIMETHYLARGININE | n/a | |
| 3 | P61964_35Q | 35Q | n/a | 91623360 | CHEMBL3798846 | N-(4-(4-methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide | n/a | |
| 4 | P61964_37F | 37F | n/a | 76871930 | CHEMBL3799275 | N-[2-(4-methylpiperazin-1-yl)-5-(quinolin-3-yl)phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide | n/a | |
| 5 | P61964_5ML | 5ML | n/a | 91995965 | CHEMBL3798573 | 3-methyl-~{N}-[2-(4-methylpiperazin-1-yl)-5-quinolin-3-yl-phenyl]benzamide | n/a | |
| 6 | P61964_5MN | 5MN | n/a | 91995966 | CHEMBL3798547 | ~{N}-[5-(1~{H}-indol-5-yl)-2-(4-methylpiperazin-1-yl)phenyl]-3-methyl-benzamide | n/a | |
| 7 | P61964_5MO | 5MO | n/a | 127046526 | CHEMBL3800374 | N-[5-(2,3-dihydro-1-benzofuran-5-yl)-2-(4-methylpiperazin-1-yl)phenyl]-3-methylbenzamide | n/a | |
| 8 | P61964_5MQ | 5MQ | n/a | 127046525 | CHEMBL3798448 | N-[5-(2,3-dihydro-1-benzofuran-7-yl)-2-(4-methylpiperazin-1-yl)phenyl]-3-methylbenzamide | n/a | |
| 9 | P61964_6IQ | 6IQ | n/a | 684718 | n/a | 1-[2,5-bis(chloranyl)phenyl]sulfonylbenzimidazole | n/a | |
| 10 | P61964_7DC | 7DC | n/a | n/a | n/a | 4-[(~{E})-[4-[[[(2~{S})-2-[[(2~{S})-2-[[(2~{S})-2-[[(2~{S})-2-azanyl-3-oxidanyl-propanoyl]amino]propanoyl]amino]-5-carbamimidamido-pentanoyl]amino]propanoyl]amino]methyl]phenyl]diazenyl]-~{N}-[(2~{S})-3-methyl-1-oxidanylidene-butan-2-yl]benzamide | n/a | |
| 11 | P61964_7DU | 7DU | n/a | n/a | n/a | (2~{S})-2-[[(2~{S})-2-[[(2~{S})-2-azanyl-3-oxidanyl-propanoyl]amino]propanoyl]amino]-5-carbamimidamido-~{N}-[(2~{S})-1-[[4-[(~{E})-[4-(hydroxymethyl)phenyl]diazenyl]phenyl]methylamino]-1-oxidanylidene-propan-2-yl]pentanamide | n/a | |
| 12 | P61964_8KH | 8KH | n/a | 157049306 | CHEMBL5092273 | N-[5-[4-[[5-[[(2S)-3,3-dimethyl-1-[(2S,4R)-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-1-oxidanylidene-butan-2-yl]amino]-5-oxidanylidene-pentyl]carbamoyl]phenyl]-2-(4-methylpiperazin-1-yl)phenyl]-6-oxidanylidene-4-(trifluoromethyl)-1H-pyridine-3-carboxamide | n/a | |
| 13 | P61964_9BA | 9BA | n/a | 129010138 | CHEMBL4116919 | N-{(3R,6S,9S,12R)-6-ethyl-12-methyl-9-[3-(N'-methylcarbamimidamido)propyl]-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetraazacyclotetradecan-12-yl}-2-methylpropanamide | n/a | |
| 14 | P61964_ARG | ARG | DB00125 | 1549073;5287702;52941769;59294017;59904234;88031296; | n/a | ARGININE | n/a | |
| 15 | P61964_BEN | BEN | n/a | 2332 | CHEMBL20936 | BENZAMIDINE | n/a | |
| 16 | P61964_BTB | BTB | n/a | 81462 | n/a | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 17 | P61964_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 18 | P61964_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 19 | P61964_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 20 | P61964_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 21 | P61964_FZM | FZM | n/a | 765511 | CHEMBL1380070 | 2-phenyl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole | n/a | |
| 22 | P61964_G1Y | G1Y | n/a | 134369552 | CHEMBL4277278 | N-{[3-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)phenyl]methyl}benzamide | n/a | |
| 23 | P61964_G2D | G2D | n/a | 137349382 | n/a | N-[(1R)-6-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)-2,3-dihydro-1H-inden-1-yl]-3-methoxy-4-methylbenzamide | n/a | |
| 24 | P61964_G2J | G2J | n/a | 134369559 | CHEMBL4294825 | N-(cyclopropylmethyl)-N-{[3-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)phenyl]methyl}-3-methoxybenzamide | n/a | |
| 25 | P61964_G2V | G2V | n/a | 137349384 | CHEMBL4281112 | 6-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)-1-methylindoline | n/a | |
| 26 | P61964_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 27 | P61964_HH7 | HH7 | n/a | 137530076 | n/a | N-[3-(2,4-dichlorophenoxy)propyl]-1H-imidazol-2-amine | n/a | |
| 28 | P61964_HHM | HHM | n/a | 137530077 | CHEMBL5176836 | N-[(3,5-dichlorophenyl)methyl]-3-[(1H-imidazol-1-yl)methyl]benzamide | n/a | |
| 29 | P61964_HLJ | HLJ | n/a | n/a | n/a | N-[(3,4-dichlorophenyl)methyl]-3-(6-fluoro-2-methylpyridin-3-yl)-5-{[(2E)-2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl]methyl}benzamide | n/a | |
| 30 | P61964_HLM | HLM | n/a | 138753247 | n/a | N-[(1S)-1-(3-chlorophenyl)ethyl]-3-{[(4,5-dihydro-1H-imidazol-2-yl)amino]methyl}benzamide | n/a | |
| 31 | P61964_HLP | HLP | n/a | 3154177 | CHEMBL5198324 | 5-[(1H-imidazol-1-yl)methyl]furan-2-carboxylic acid | n/a | |
| 32 | P61964_HLS | HLS | n/a | 138753248 | CHEMBL5172311 | 3-{[(4,5-dihydro-1H-imidazol-2-yl)amino]methyl}-N-[(3,5-dimethoxyphenyl)methyl]-4-fluorobenzamide | n/a | |
| 33 | P61964_IA9 | IA9 | n/a | 70679466 | CHEMBL2337032 | 2-chloro-4-fluoro-3-methyl-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide | n/a | |
| 34 | P61964_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 35 | P61964_M4U | M4U | n/a | 153572432 | CHEMBL5202831 | (5P)-2-[(3,5-dimethoxyphenyl)methyl]-7-[(2-methyl-1H-imidazol-1-yl)methyl]-5-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-3,4-dihydroisoquinolin-1(2H)-one | n/a | |
| 36 | P61964_MBU | MBU | n/a | 153572417 | CHEMBL5190717 | (5P)-2-[(S)-cyclopropyl(4-methylpyridin-2-yl)methyl]-5-[1-ethyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-[(2-methyl-1H-imidazol-1-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one | n/a | |
| 37 | P61964_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 38 | P61964_NMM | NMM | DB11815 | 132862;46906075; | CHEMBL256147 | (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid | n/a | |
| 39 | P61964_NP7 | NP7 | n/a | 2965974 | CHEMBL1609857 | 2-chloro-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide | n/a | |
| 40 | P61964_OGM | OGM | n/a | 145704658 | n/a | methyl {4-[5-(hydroxymethyl)-1H-imidazol-2-yl]butyl}carbamate | n/a | |
| 41 | P61964_OGY | OGY | n/a | 145704656 | n/a | [2-(3-phenylpropyl)-1H-imidazol-4-yl]methanol | n/a | |
| 42 | P61964_OH1 | OH1 | n/a | 145704657 | n/a | N-{4-[4-(hydroxymethyl)-1H-imidazol-2-yl]butyl}benzamide | n/a | |
| 43 | P61964_OH4 | OH4 | n/a | 145704655 | n/a | {2-[(3S)-3-methoxy-3-phenylpropyl]-1H-imidazol-4-yl}methanol | n/a | |
| 44 | P61964_OH7 | OH7 | n/a | 145704654 | n/a | N-{4-[4-(hydroxymethyl)-1H-imidazol-2-yl]butyl}acetamide | n/a | |
| 45 | P61964_OHG | OHG | n/a | 11480420 | n/a | (2-methyl-1H-imidazol-4-yl)methanol | n/a | |
| 46 | P61964_OHJ | OHJ | n/a | 2735673 | n/a | (2-butyl-1H-imidazol-4-yl)methanol | n/a | |
| 47 | P61964_OHV | OHV | n/a | 145704653 | n/a | benzyl {4-[5-(hydroxymethyl)-1H-imidazol-2-yl]butyl}carbamate | n/a | |
| 48 | P61964_OJG | OJG | n/a | 145704659 | n/a | N-{4-[5-(hydroxymethyl)-1H-imidazol-2-yl]butyl}-2-phenylacetamide | n/a | |
| 49 | P61964_OJJ | OJJ | n/a | 145704660 | n/a | methyl benzyl{4-[4-(hydroxymethyl)-1H-imidazol-2-yl]butyl}carbamate | n/a | |
| 50 | P61964_OJM | OJM | n/a | 145704662 | n/a | ethyl 3-[4-(hydroxymethyl)-1H-imidazol-2-yl]propanoate | n/a | |
| 51 | P61964_OJP | OJP | n/a | 145704663 | n/a | N-{4-[4-(hydroxymethyl)-1H-imidazol-2-yl]butyl}prop-2-enamide | n/a | |
| 52 | P61964_OK4 | OK4 | n/a | 145704661 | n/a | N-acetyl-L-alanyl-5-[5-(hydroxymethyl)-1H-imidazol-2-yl]-L-norvalyl-L-valinamide | n/a | |
| 53 | P61964_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 54 | P61964_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 55 | P61964_Q0M | Q0M | n/a | 145704698 | CHEMBL4472649 | 3-{[(5-bromo-3-chloro-2-hydroxyphenyl)sulfonyl]amino}-5-(1-cyanocyclobutyl)-2-hydroxy-N-methylbenzamide | n/a | |
| 56 | P61964_Q0S | Q0S | n/a | 145704697 | CHEMBL4475470 | 5-bromo-2-hydroxy-N-[3-(methylsulfonyl)-5-(pentafluoro-lambda~6~-sulfanyl)phenyl]benzene-1-sulfonamide | n/a | |
| 57 | P61964_Q0Y | Q0Y | n/a | 44117787 | CHEMBL4514537 | 5-bromo-N-(5-chloro-2-hydroxyphenyl)-2-methoxybenzene-1-sulfonamide | n/a | |
| 58 | P61964_Q1G | Q1G | n/a | 145704703 | CHEMBL4470498 | 5-bromo-N-[5-(1-cyanocyclobutyl)-2-hydroxyphenyl]-2-hydroxybenzene-1-sulfonamide | n/a | |
| 59 | P61964_Q1J | Q1J | n/a | 145704699 | CHEMBL4443499 | 5-bromo-N-(4-hydroxy[1,1'-biphenyl]-3-yl)-2-methoxybenzene-1-sulfonamide | n/a | |
| 60 | P61964_Q1M | Q1M | n/a | 145704700 | CHEMBL4515727 | 3-{[(5-bromo-2-methoxyphenyl)sulfonyl]amino}-5-chloro-2-hydroxybenzoic acid | n/a | |
| 61 | P61964_Q1P | Q1P | n/a | 145704701 | CHEMBL4471200 | 3-{[(5-bromo-2-hydroxyphenyl)sulfonyl]amino}-5-cyclopropyl-6-fluoro-2-hydroxybenzoic acid | n/a | |
| 62 | P61964_Q1S | Q1S | n/a | 145704702 | n/a | N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]isoquinolin-1-amine | n/a | |
| 63 | P61964_Q3R | Q3R | n/a | 165416423 | CHEMBL5185035 | ~{N}-[5-[4-[[4-[[(2~{S})-3,3-dimethyl-1-[(2~{S},4~{R})-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-1-oxidanylidene-butan-2-yl]amino]-4-oxidanylidene-butyl]carbamoyl]phenyl]-2-(4-methylpiperazin-1-yl)phenyl]-6-oxidanyl-4-(trifluoromethyl)pyridine-3-carboxamide | n/a | |
| 64 | P61964_Q3X | Q3X | n/a | 165416422 | n/a | ~{N}-[5-[4-[2-[2-[2-[2-[3-[[3,3-dimethyl-1-[(2~{S},4~{R})-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-1-oxidanylidene-butan-2-yl]amino]-3-oxidanylidene-propoxy]ethoxy]ethoxy]ethoxy]ethylcarbamoyl]phenyl]-2-(4-methylpiperazin-1-yl)phenyl]-6-oxidanylidene-4-(trifluoromethyl)-3~{H}-pyridine-3-carboxamide | n/a | |
| 65 | P61964_Q41 | Q41 | n/a | 145714284 | n/a | 2-amino-3-{[(5P)-2-[(3,5-dimethoxyphenyl)methyl]-5-(4-fluoro-2-methylphenyl)-1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl]methyl}-1-methyl-1H-imidazol-3-ium | n/a | |
| 66 | P61964_Q43 | Q43 | n/a | 165416424 | CHEMBL5201006 | ~{N}-[5-[4-[[4-[2-[[(2~{S})-3,3-dimethyl-1-[(2~{S},4~{R})-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-1-oxidanylidene-butan-2-yl]amino]-2-oxidanylidene-ethyl]phenyl]methylcarbamoyl]phenyl]-2-(4-methylpiperazin-1-yl)phenyl]-6-oxidanyl-4-(trifluoromethyl)pyridine-3-carboxamide | n/a | |
| 67 | P61964_Q6S | Q6S | n/a | n/a | n/a | N-[(3,5-dimethoxyphenyl)methyl]-4'-fluoro-5-{[(2E)-2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl]methyl}-2'-methyl[1,1'-biphenyl]-3-carboxamide | n/a | |
| 68 | P61964_Q8D | Q8D | n/a | 653819 | CHEMBL383099 | 1-cyclohexyl-1H-benzotriazole-5-carboxylic acid | n/a | |
| 69 | P61964_Q8G | Q8G | n/a | 513903 | CHEMBL177122 | 1-cyclohexyl-1H-benzimidazole-5-carboxylic acid | n/a | |
| 70 | P61964_Q8M | Q8M | n/a | 146019257 | CHEMBL4633372 | 5-bromo-3-chloro-N-(1-cyclopentyl-1H-imidazol-4-yl)-2-hydroxybenzene-1-sulfonamide | n/a | |
| 71 | P61964_Q8P | Q8P | n/a | 146019256 | CHEMBL4641743 | 4-{[(5-bromo-3-chloro-2-hydroxyphenyl)sulfonyl]amino}-1-cyclopentyl-N-methyl-1H-imidazole-2-carboxamide | n/a | |
| 72 | P61964_Q8S | Q8S | n/a | 146019258 | CHEMBL4637994 | 5-bromo-3-chloro-N-(1-cyclopentyl-2-methyl-1H-imidazol-4-yl)-2-hydroxybenzene-1-sulfonamide | n/a | |
| 73 | P61964_QBM | QBM | n/a | 1555395;135453711; | n/a | 6-methyl-3-(propylsulfanyl)-1,2,4-triazin-5-ol | n/a | |
| 74 | P61964_QBP | QBP | n/a | 342565 | n/a | 5-[4-(trifluoromethyl)phenyl]-1H-tetrazole | n/a | |
| 75 | P61964_QBS | QBS | n/a | 773171 | n/a | (2R)-2-(4-chlorophenyl)-3-oxobutanenitrile | n/a | |
| 76 | P61964_QF1 | QF1 | n/a | 146019259 | CHEMBL4645862 | 5-bromo-3-chloro-N-[1-cyclopentyl-2-(methylsulfonyl)-1H-imidazol-4-yl]-2-hydroxybenzene-1-sulfonamide | n/a | |
| 77 | P61964_SCN | SCN | n/a | 9322 | n/a | THIOCYANATE ION | n/a | |
| 78 | P61964_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 79 | P61964_TRS | TRS | DB03754 | 3777159;88088752;152743085; | n/a | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 80 | P61964_UNX | UNX | n/a | |||||
| 81 | P61964_UY9 | UY9 | n/a | 166449496 | CHEMBL5421916 | 6-ethyl-4-[(5P)-7-[(1H-imidazol-1-yl)methyl]-5-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-1-oxo-3,4-dihydroisoquinolin-2(1H)-yl]-N-methylquinoline-8-carboxamide | n/a | |
| 82 | P61964_VKA | VKA | n/a | 156613452 | n/a | 3-methyl-N-(11-{[2-(4-{[4'-(4-methylpiperazin-1-yl)-3'-{[6-oxo-4-(trifluoromethyl)-5,6-dihydropyridine-3-carbonyl]amino}[1,1'-biphenyl]-3-yl]methyl}piperazin-1-yl)ethyl]amino}-11-oxoundecanoyl)-L-valyl-(4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-L-prolinamide | n/a | |
| 83 | P61964_X6M | X6M | n/a | 153379992 | CHEMBL5415680 | N-(6-fluoro-3'-{[6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carbonyl]amino}-4'-[(3R,5S)-3,4,5-trimethylpiperazin-1-yl][1,1'-biphenyl]-3-carbonyl)glycyl-3-methyl-L-valyl-(4R)-4-hydroxy-N-{(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl}-L-prolinamide | n/a | |
| 84 | P61964_X8N | X8N | n/a | 68755219 | n/a | (2S)-2-({(2S)-3-(3'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-1-[(1H-tetrazol-5-yl)amino]propan-2-yl}oxy)propanoic acid | n/a | |
| 85 | P61964_XKN | XKN | n/a | 168451739 | n/a | 3-ethynyl-5-{[(3R)-4-{1-[(2-methoxyphenyl)methyl]-1H-benzimidazole-5-carbonyl}-3-methylpiperazin-1-yl]methyl}benzene-1-sulfonyl fluoride | n/a | |
| 86 | P61964_YJN | YJN | n/a | 168354957 | CHEMBL5429278 | N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxamide | n/a | |
| 87 | P61964_YJR | YJR | n/a | 168354958 | CHEMBL5441050 | (1M)-N-[(3,5-difluoro[1,1'-biphenyl]-4-yl)methyl]-6-methyl-4-oxo-1-(pyridin-3-yl)-1,4-dihydropyridazine-3-carboxamide | n/a | |
| 88 | P61964_ZHF | ZHF | n/a | 168433904 | n/a | N-[(2S)-1-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-1-oxopentan-2-yl]-3-[(1H-imidazol-1-yl)methyl]benzamide | n/a | |
| 89 | P61964_SRO | SRO | DB08839 | 5202 | CHEMBL39 | SEROTONIN | n/a |