Gene name: FKBP1A
Protein name: Peptidyl-prolyl cis-trans isomerase
List of molecules and drugs that interact with protein P62942
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P62942_001 | 001 | DB02888 | 446414 | n/a | 1-[2,2-DIFLUORO-2-(3,4,5-TRIMETHOXY-PHENYL)-ACETYL]-PIPERIDINE-2-CARBOXYLIC ACID 4-PHENYL-1-(3-PYRIDIN-3-YL-PROPYL)-BUTYL ESTER | inhibitor | |
| 2 | P62942_0AN | 0AN | n/a | 168451627 | n/a | (1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-[(~{E})-2-(2-chlorophenyl)ethenyl]-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 3 | P62942_587 | 587 | DB03621 | 5496872 | n/a | C32-O-(1-METHYL-INDOL-5-YL) 18-HYDROXY-ASCOMYCIN | inhibitor | |
| 4 | P62942_60Z | 60Z | n/a | 146025966 | n/a | (3R,4E,7E,10R,11S,12R,13S,16R,17R,24aS)-11,17-dihydroxy-10,12,16-trimethyl-3-[(2R)-1-phenylbutan-2-yl]-6,9,10,11,12,13,14,15,16,17,22,23,24,24a-tetradecahydro-3H-13,17-epoxypyrido[2,1-c][1,4]oxazacyclohenicosine-1,18,19(21H)-trione | n/a | |
| 5 | P62942_818 | 818 | n/a | 445642 | n/a | 18-HYDROXYASCOMYCIN | n/a | |
| 6 | P62942_858 | 858 | n/a | 5496870 | n/a | C32-O-(1-ETHYL-INDOL-5-YL)ASCOMYCIN | n/a | |
| 7 | P62942_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 8 | P62942_AP1 | AP1 | DB01723 | 444590 | CHEMBL110674 | {3-[3-(3,4-DIMETHOXY-PHENYL)-1-(1-{1-[2-(3,4,5-TRIMETHOXY-PHENYL)-BUTYRYL]-PIPERIDIN-2YL}-VINYLOXY)-PROPYL]-PHENOXY}-ACETIC ACID | n/a | |
| 9 | P62942_ARD | ARD | n/a | 6323222 | CHEMBL263850 | C15-(R)-METHYLTHIENYL RAPAMYCIN | n/a | |
| 10 | P62942_B7G | B7G | DB03338 | 448173 | n/a | heptyl beta-D-glucopyranoside | inhibitor | |
| 11 | P62942_BUQ | BUQ | DB04094 | 111509 | n/a | 4-HYDROXY-2-BUTANONE | inhibitor | |
| 12 | P62942_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 13 | P62942_CD | CD | n/a | 31193 | n/a | CADMIUM ION | n/a | |
| 14 | P62942_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 15 | P62942_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 16 | P62942_DSS | DSS | DB02311 | 9543427 | n/a | METHYL METHYLSULFINYLMETHYL SULFIDE | inhibitor | |
| 17 | P62942_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 18 | P62942_FK5 | FK5 | DB00864 | 445643 | CHEMBL269732 | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | inhibitor | Ki(nM) = 0.4 IC50(nM) = 2.3 Kd(nM) = 0.2 |
| 19 | P62942_FKA | FKA | n/a | 444177 | n/a | BENZYL-CARBAMIC ACID [8-DEETHYL-ASCOMYCIN-8-YL]ETHYL ESTER | n/a | |
| 20 | P62942_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 21 | P62942_GPI | GPI | DB01951 | 445501 | CHEMBL6367 | (2S)-[3-PYRIDYL-1-PROPYL]-1-[3,3-DIMETHYL-1,2-DIOXOPENTYL]-2-PYRROLIDINECARBOXYLATE | inhibitor | Ki(nM) = 0.01 IC50(nM) = 1240.0 |
| 22 | P62942_LWR | LWR | n/a | 165111563 | n/a | (3S,5Z,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-5-(ethoxyimino)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone | n/a | |
| 23 | P62942_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 24 | P62942_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 25 | P62942_MPD | MPD | DB03564 | 5288834 | n/a | (4S)-2-METHYL-2,4-PENTANEDIOL | n/a | |
| 26 | P62942_MR8 | MR8 | n/a | 137349761 | n/a | 28-O-Methylrapamycin | n/a | |
| 27 | P62942_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 28 | P62942_NH4 | NH4 | n/a | 223;16741146; | n/a | AMMONIUM ION | n/a | |
| 29 | P62942_OOZ | OOZ | n/a | 6450137 | n/a | (1~{R},9~{S},12~{S},13~{R},14~{S},17~{R},18~{E},21~{S},23~{S},24~{R},25~{S},27~{R})-17-ethyl-25-methoxy-12-[(~{E})-1-[(1~{R},3~{R},4~{R})-3-methoxy-4-oxidanyl-cyclohexyl]prop-1-en-2-yl]-13,19,21,27-tetramethyl-1,14,23-tris(oxidanyl)-11,28-dioxa-4-azatricyclo[22.3.1.0^{4,9}]octacos-18-ene-2,3,10,16-tetrone | n/a | |
| 30 | P62942_OP5 | OP5 | n/a | 9811140 | n/a | (1~{R},9~{S},12~{S},13~{R},14~{S},17~{R},18~{E},21~{S},23~{S},24~{R},25~{S},27~{R})-23,25-dimethoxy-12-[(~{E})-1-[(1~{R},3~{R},4~{R})-3-methoxy-4-oxidanyl-cyclohexyl]prop-1-en-2-yl]-13,19,21,27-tetramethyl-1,14-bis(oxidanyl)-17-(2-oxidanylidenepropyl)-11,28-dioxa-4-azatricyclo[22.3.1.0^{4,9}]octacos-18-ene-2,3,10,16-tetrone | n/a | |
| 31 | P62942_OP8 | OP8 | n/a | 134488566 | n/a | (1aR,3R,5S,6R,7S,9R,10R,17aS,20S,21R,22S,25R,25aR)-25-Ethyl-10,22-dihydroxy-20-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-5,7-dimethoxy-1a,3,9,21-tetramethyloctadecahydro-2H-6,10-epoxyoxireno[p]pyrido[2,1-c][1,4]oxazacyclotricosine-11,12,18,24(1aH,14H)-tetrone | n/a | |
| 32 | P62942_PE8 | PE8 | n/a | 78798 | n/a | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL | n/a | |
| 33 | P62942_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 34 | P62942_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 35 | P62942_R27 | R27 | n/a | 155804519 | n/a | N'-[(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-1,20,21-trioxo-8-(prop-2-en-1-yl)-1,3,4,5,6,8,11,12,13,14,15,16,17,18,19,20,21,23,24,25,26,26a-docosahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosin-7-ylidene]acetohydrazide | n/a | |
| 36 | P62942_RAD | RAD | n/a | 5289261 | CHEMBL4287588 | C49-METHYL RAPAMYCIN | n/a | |
| 37 | P62942_RAP | RAP | DB00877 | 5284616 | CHEMBL413 | RAPAMYCIN IMMUNOSUPPRESSANT DRUG | n/a | |
| 38 | P62942_SB1 | SB1 | DB08520 | 445646 | CHEMBL1235837 | (21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE | n/a | |
| 39 | P62942_SB3 | SB3 | n/a | 445644 | CHEMBL126568 | 1,3-DIPHENYL-1-PROPYL-1-(3,3-DIMETHYL-1,2-DIOXYPENTYL)-2-PIPERIDINE CARBOXYLATE | n/a | |
| 40 | P62942_SBX | SBX | n/a | 44338250 | CHEMBL321038 | 1-CYCLOHEXYL-3-PHENYL-1-PROPYL-1-(3,3-DIMETHYL-1,2-DIOXYPENTYL)-2-PIPERIDINE CARBOXYLATE | n/a | |
| 41 | P62942_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 42 | P62942_TST | TST | DB04012 | 446411 | n/a | 4-METHYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PENTANOIC ACID | n/a | |
| 43 | P62942_UMR | UMR | n/a | 168477221 | n/a | (1S,5S,6R)-10-[S-[3,5-bis(chloranyl)phenyl]-N-methyl-sulfonimidoyl]-5-ethenyl-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 44 | P62942_UQI | UQI | n/a | 168477831 | n/a | (1S,5S,6R)-10-[[3,5-bis(chloranyl)phenyl]sulfonimidoyl]-5-ethenyl-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 45 | P62942_USV | USV | n/a | 168477832 | n/a | (1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-ethenyl-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 46 | P62942_UT6 | UT6 | n/a | 168477222 | n/a | (1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfinyl-5-ethenyl-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 47 | P62942_UUI | UUI | n/a | 168477833 | n/a | (1S,5S,6R)-10-[[3,5-bis(chloranyl)phenyl]sulfonimidoyl]-5-ethenyl-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 48 | P62942_XYU | XYU | n/a | 153276549 | CHEMBL5418335 | (3S,5R,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-5,9,27-trihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone | n/a | |
| 49 | P62942_XZ3 | XZ3 | n/a | 153276605 | CHEMBL5431157 | (3S,5R,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-5,10,21-trimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone | n/a | |
| 50 | P62942_Y5Q | Y5Q | n/a | 169452787 | n/a | (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[4-[(1~{S})-1-[(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-ethenyl-2-oxidanylidene-3,10-diazabicyclo[4.3.1]decan-3-yl]ethyl]-1,2,3-triazol-1-yl]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide | n/a | |
| 51 | P62942_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 52 | P62942_SUB | SUB | DB01712 | 46936196 | n/a | 3-PHENYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PROPIONIC ACID ETHYL ESTER | n/a | |
| 53 | P62942_DB00337 | n/a | DB00337 | n/a | n/a | Pimecrolimus | potentiator | |
| 54 | P62942_DB05814 | n/a | DB05814 | n/a | n/a | GPI-1485 | binder | |
| 55 | P62942_MYR | MYR | DB08231 | 11005 | CHEMBL111077 | Myristic acid | inhibitor | |
| 56 | P62942_TAK | TAK | DB08597 | 11524144 | CHEMBL478629 | Dorsomorphin | n/a |