Gene name: gyrB
Protein name: DNA gyrase subunit
List of molecules and drugs that interact with protein P66937
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P66937_50M | 50M | n/a | 7298502 | CHEMBL1276314 | (2R,4S,4aS,5R)-6'-hydroxy-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4'(3'H)-dione | n/a | |
| 2 | P66937_53L | 53L | n/a | 7298502 | CHEMBL1276314 | (2R,4S,4aS,5S)-6'-hydroxy-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4'(3'H)-dione | n/a | |
| 3 | P66937_53M | 53M | n/a | 7298502 | CHEMBL1276314 | (2R,4S,4aS)-4',6'-dihydroxy-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidin]-2'-one | n/a | |
| 4 | P66937_54Q | 54Q | n/a | 7298502 | CHEMBL1276314 | (2R,4S,4aS)-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4',6'(1'H,3'H)-trione | n/a | |
| 5 | P66937_5UA | 5UA | n/a | 49866542 | n/a | 5'-O-CARBOXY-2'-DEOXYADENOSINE | n/a | |
| 6 | P66937_61I | 61I | n/a | 172444106 | CHEMBL5404831 | 4-{[(1-{[(6R)-1-chloro-6,7-dihydro-5H-cyclopenta[c]pyridin-6-yl]methyl}azetidin-3-yl)methyl]amino}-6-fluoro-2H-1-benzopyran-2-one | n/a | |
| 7 | P66937_6EJ | 6EJ | DB15345 | 119057475 | CHEMBL3793226 | (1R)-1-[(4-{[(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl]amino}piperidin-1-yl)methyl]-9-fluoro-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one | n/a | |
| 8 | P66937_6I0 | 6I0 | n/a | 156861769 | CHEMBL5403672 | 6-{(5R)-5-[2-({[(2R)-4-chloro-2,3-dihydro-1H-inden-2-yl]methyl}amino)ethyl]-2-oxo-1,3-oxazolidin-3-yl}-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one | n/a | |
| 9 | P66937_94H | 94H | n/a | 129012087 | n/a | ~{N}-[(1~{R})-2-azanyl-1-phenyl-ethyl]-4-(1~{H}-pyrrolo[2,3-b]pyridin-3-yl)thiophene-2-carboxamide | n/a | |
| 10 | P66937_94K | 94K | n/a | 129012089 | CHEMBL4443422 | ~{N}-[(1~{R})-2-azanyl-1-phenyl-ethyl]-5-(2-chlorophenyl)-2-methyl-thiophene-3-carboxamide | n/a | |
| 11 | P66937_9JN | 9JN | n/a | 129012088 | n/a | ~{N}-[(1~{S})-2-azanyl-1-phenyl-ethyl]-4-(1~{H}-pyrrolo[2,3-b]pyridin-3-yl)thiophene-2-carboxamide | n/a | |
| 12 | P66937_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 13 | P66937_AE8 | AE8 | n/a | 23633343 | CHEMBL2424928 | (S)-4-((4-(((2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methyl)amino)piperidin-1-yl)methyl)-3-fluoro-4-hydroxy-4H-pyrrolo[3,2,1-de][1,5]naphthyridin-7(5H)-one | n/a | |
| 14 | P66937_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 15 | P66937_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 16 | P66937_CPF | CPF | DB00537 | 2764;4011971; | CHEMBL8 | 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID | n/a | |
| 17 | P66937_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 18 | P66937_DU5 | DU5 | n/a | 121417711 | CHEMBL4544573 | ~{N}-[3-(4-isoquinolin-1-ylpiperazin-1-yl)propyl]benzamide | n/a | |
| 19 | P66937_E32 | E32 | n/a | 132473042 | CHEMBL4210894 | 7-[(3~{S})-3-azanylpyrrolidin-1-yl]-5-cyclopropyl-8-fluoranyl-imidazo[1,2-a]quinoxalin-4-one | n/a | |
| 20 | P66937_E3E | E3E | n/a | 132473043 | CHEMBL4203118 | 5-cyclopropyl-8-fluoranyl-7-pyridin-4-yl-imidazo[1,2-a]quinoxalin-4-one | n/a | |
| 21 | P66937_EVP | EVP | DB00773 | 36462 | CHEMBL44657 | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside | n/a | |
| 22 | P66937_GLY | GLY | DB00145 | 750;5257127; | CHEMBL773 | GLYCINE | n/a | |
| 23 | P66937_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 24 | P66937_JK8 | JK8 | n/a | 137796790 | CHEMBL4445556 | (2~{R})-2-[[5-(2-chlorophenyl)-1,2-benzoxazol-3-yl]oxy]-2-phenyl-ethanamine | n/a | |
| 25 | P66937_MFX | MFX | DB00218 | 152946;40467042; | CHEMBL32 | 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | n/a | |
| 26 | P66937_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 27 | P66937_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 28 | P66937_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 29 | P66937_R8U | R8U | DB12817 | 76685216 | CHEMBL3544978 | Zoliflodacin | n/a | |
| 30 | P66937_RXV | RXV | n/a | 46835136 | CHEMBL1235773 | 6-METHOXY-4-(2-{4-[([1,3]OXATHIOLO[5,4-C]PYRIDIN-6-YLMETHYL)AMINO]PIPERIDIN-1-YL}ETHYL)QUINOLINE-3-CARBONITRILE | n/a | |
| 31 | P66937_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a |