Gene name: parC
Protein name: DNA topoisomerase 4
List of molecules and drugs that interact with protein P72525
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P72525_1UV | 1UV | n/a | 44479851 | CHEMBL4637365 | (3aS,4R)-4-amino-13-cyclopropyl-8-fluoro-10-oxo-3a,4,5,6,10,13-hexahydro-1H,3H-pyrrolo[2',1':3,4][1,4]oxazepino[5,6-h]quinoline-11-carboxylic acid | n/a | |
| 2 | P72525_AF5 | AF5 | n/a | 44480356 | CHEMBL4642209 | (7aR,8R)-8-amino-4-cyclopropyl-12-fluoro-1-oxo-4,7,7a,8,9,10-hexahydro-1H-pyrrolo[1',2':1,7]azepino[2,3-h]quinoline-2-carboxylic acid | n/a | |
| 3 | P72525_LFX | LFX | DB01137 | 149096;6956357; | CHEMBL33 | (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid | n/a | |
| 4 | P72525_MFX | MFX | DB00218 | 152946;40467042; | CHEMBL32 | 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | n/a | |
| 5 | P72525_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 6 | P72525_NFX | NFX | n/a | 1402478;1402479; | CHEMBL113334 | 7-[(3R)-3-aminopyrrolidin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | n/a | |
| 7 | P72525_PDQ | PDQ | n/a | 11325896 | CHEMBL383917 | 3-amino-7-{(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl}-1-cyclopropyl-6-fluoro-8-methylquinazoline-2,4(1H,3H)-dione | n/a | |
| 8 | P72525_TR6 | TR6 | DB00685 | n/a | CHEMBL428 | Trovafloxacin | n/a |