Gene name: gyrB
Protein name: DNA gyrase subunit
List of molecules and drugs that interact with protein P9WG45
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P9WG45_8MX | 8MX | n/a | 59050920 | n/a | 1-cyclopropyl-6-fluoro-8-methyl-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | n/a | |
| 2 | P9WG45_CPF | CPF | DB00537 | 2764;4011971; | CHEMBL8 | 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID | n/a | IC50(nM) = 10600.0 |
| 3 | P9WG45_GFN | GFN | n/a | 1150508;6971135; | CHEMBL428581 | 1-cyclopropyl-6-fluoro-8-methoxy-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | n/a | |
| 4 | P9WG45_LFX | LFX | DB01137 | 149096;6956357; | CHEMBL33 | (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid | n/a | |
| 5 | P9WG45_MFX | MFX | DB00218 | 152946;40467042; | CHEMBL32 | 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | n/a | IC50(nM) = 4980.0 |
| 6 | P9WG45_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a |