Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
P9WNX1 DYR_MYCTU
Gene name: folA
Protein name: Dihydrofolate reductase (EC

List of molecules and drugs that interact with protein P9WNX1

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P9WNX1_1CY 1CY DB14763 9049 CHEMBL747 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine n/a
2 P9WNX1_4RG 4RG n/a 3729884 CHEMBL4638554 3-(phenoxymethyl)benzoic acid n/a
3 P9WNX1_ACT ACT DB14511 175 n/a ACETATE ION n/a
4 P9WNX1_BR BR n/a 259 n/a BROMIDE ION n/a
5 P9WNX1_CL CL n/a 312 n/a CHLORIDE ION n/a
6 P9WNX1_CO CO n/a 104729 n/a COBALT (II) ION n/a
7 P9WNX1_CP6 CP6 DB00205 4993 CHEMBL36 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE n/a
8 P9WNX1_DHF DHF DB02015 98792;5280349;135398604; CHEMBL46294 DIHYDROFOLIC ACID n/a
9 P9WNX1_EDO EDO n/a 174 CHEMBL457299 1,2-ETHANEDIOL n/a
10 P9WNX1_FMT FMT DB01942 284;18971002; CHEMBL116736 FORMIC ACID n/a
11 P9WNX1_G6Y G6Y n/a 124081251 CHEMBL3828485 3'-[(2R)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-5'-methoxy[1,1'-biphenyl]-4-carboxylic acid n/a
12 P9WNX1_G7D G7D n/a 133107902;135567415; n/a N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}-2-hydroxybenzene-1-carbonyl)-L-glutamic acid n/a
13 P9WNX1_GHU GHU n/a 68574580 n/a ethyl 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoate n/a
14 P9WNX1_GOL GOL DB09462 753 CHEMBL692 GLYCEROL n/a
15 P9WNX1_GQO GQO n/a 162540396 n/a 2-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-N,N-dimethylethane-1-sulfonamide n/a
16 P9WNX1_GUU GUU n/a 162540395 n/a 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-N-(methanesulfonyl)propanamide n/a
17 P9WNX1_GWL GWL n/a 162540397 n/a 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanamide n/a
18 P9WNX1_GXC GXC n/a 162540398 n/a N-[2-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)ethanesulfonyl]acetamide n/a
19 P9WNX1_GXJ GXJ n/a n/a n/a (2R)-3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-2-methylpropanoic acid n/a
20 P9WNX1_GYI GYI n/a 162540400 n/a 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-N-(propane-2-sulfonyl)propanamide n/a
21 P9WNX1_H03 H03 n/a 162540401 n/a 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-N-(dimethylsulfamoyl)propanamide n/a
22 P9WNX1_H0I H0I n/a 162540402 n/a 4-(3-{4-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]butoxy}phenyl)butanoic acid n/a
23 P9WNX1_H4U H4U n/a 162540403 n/a 6-ethyl-5-(4-{3-[3-(1H-tetrazol-5-yl)propyl]phenoxy}butoxy)pyrimidine-2,4-diamine n/a
24 P9WNX1_H6O H6O n/a 162540404 n/a (2S)-4-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)butane-1,2-diol n/a
25 P9WNX1_H9I H9I n/a 162540410 n/a 3-{2-[(3-{[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]methyl}oxetan-3-yl)methoxy]phenyl}propanoic acid n/a
26 P9WNX1_HEI HEI n/a 162540406 n/a 1-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)piperidine-4-carboxylic acid n/a
27 P9WNX1_HI9 HI9 n/a n/a n/a (2E)-3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}pyridin-3-yl)prop-2-en-1-ol n/a
28 P9WNX1_HIK HIK n/a 162540408 n/a 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}pyridin-3-yl)propan-1-ol n/a
29 P9WNX1_HJI HJI n/a 162540405 n/a (2R)-2-[(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)methyl]-3,3-difluoropropanoic acid n/a
30 P9WNX1_HVR HVR n/a 162540411 n/a 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}pyridin-3-yl)prop-2-yn-1-ol n/a
31 P9WNX1_HWI HWI n/a 162540412 n/a 1-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}-4-methylphenyl)azetidine-3-carboxylic acid n/a
32 P9WNX1_I6J I6J n/a 162540409 n/a (2S)-2-[(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)methyl]-3,3-difluoropropanoic acid n/a
33 P9WNX1_IMD IMD DB03366 444234;4434133;21983501; n/a IMIDAZOLE n/a
34 P9WNX1_IOD IOD n/a 30165 n/a IODIDE ION n/a
35 P9WNX1_JBB JBB n/a 2819674 n/a 3-(thiophen-2-ylsulfanylmethyl)benzoic acid n/a
36 P9WNX1_LYA LYA DB00642 446556;5288715;135410875; CHEMBL225072 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID n/a
37 P9WNX1_MES MES DB03814 78165;4478249; CHEMBL1234276 2-(N-MORPHOLINO)-ETHANESULFONIC ACID n/a
38 P9WNX1_MMV MMV n/a 66563688 CHEMBL3040038 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid n/a
39 P9WNX1_NA NA n/a 923 n/a SODIUM ION n/a
40 P9WNX1_NAP NAP DB03461 5885;57525501; CHEMBL295069 NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE n/a
41 P9WNX1_NDP NDP DB02338 5884;134821689; CHEMBL407009 NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE n/a
42 P9WNX1_P33 P33 DB03394 79718 n/a 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL n/a
43 P9WNX1_PO4 PO4 DB14523 1061 n/a PHOSPHATE ION n/a
44 P9WNX1_RKY RKY n/a 2775652 CHEMBL1349957 4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-4-oxobutanoic acid n/a
45 P9WNX1_RPJ RPJ n/a 146675154 n/a 1-(4-fluorophenyl)-5-[3-(1H-indol-3-yl)propoxy]-1H-pyrazole-4-carboxylic acid n/a
46 P9WNX1_RQ4 RQ4 n/a 2795963 CHEMBL1455726 6-methyl-5-(4-phenyl-1,3-thiazol-2-yl)-2-(trifluoromethyl)pyridine-3-carboxylic acid n/a
47 P9WNX1_SO4 SO4 DB14546 1117 n/a SULFATE ION n/a
48 P9WNX1_U75 U75 n/a 123133740 CHEMBL3828771 4-[3-[3-[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]prop-2-ynyl]-5-methoxy-phenyl]benzoic acid n/a
49 P9WNX1_X0V X0V n/a 520822 CHEMBL1236744 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE n/a