Gene name: CDK5
Protein name: Cyclin-dependent kinase 5
List of molecules and drugs that interact with protein Q00535
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q00535_3O0 | 3O0 | n/a | 1484830 | CHEMBL1614763 | {4-amino-2-[(4-chlorophenyl)amino]-1,3-thiazol-5-yl}(3-nitrophenyl)methanone | n/a | |
| 2 | Q00535_61U | 61U | n/a | 162640251 | CHEMBL5080566 | 5-fluoranyl-4-[[2-[(1R)-1-(1-methylpiperidin-4-yl)-1-oxidanyl-ethyl]-1,6-naphthyridin-7-yl]amino]-2-morpholin-4-yl-benzenecarbonitrile | n/a | |
| 3 | Q00535_63I | 63I | n/a | 162439820 | CHEMBL5078762 | (1R)-1-[7-[(2-fluoranyl-4-pyrazol-1-yl-phenyl)amino]-1,6-naphthyridin-2-yl]-1-(1-methylpiperidin-4-yl)ethanol | n/a | |
| 4 | Q00535_64V | 64V | n/a | 156212404 | CHEMBL5093012 | 2-[[7-[[2-fluoranyl-4-[3-(hydroxymethyl)pyrazol-1-yl]phenyl]amino]-1,6-naphthyridin-2-yl]-(1-methylpiperidin-4-yl)amino]ethanoic acid | n/a | |
| 5 | Q00535_65L | 65L | n/a | 71766886 | CHEMBL5088480 | [1-[3-fluoranyl-4-[(2-piperidin-4-yloxy-1,6-naphthyridin-7-yl)amino]phenyl]pyrazol-3-yl]methanol | n/a | |
| 6 | Q00535_ALH | ALH | DB07364 | 448912 | CHEMBL75680 | 6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE | n/a | IC50(nM) = 200.0 |
| 7 | Q00535_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 8 | Q00535_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 9 | Q00535_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 10 | Q00535_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 11 | Q00535_IXM | IXM | DB02052 | n/a | CHEMBL216543 | (Z)-1H,1'H-[2,3']BIINDOLYLIDENE-3,2'-DIONE-3-OXIME | inhibitor | |
| 12 | Q00535_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 13 | Q00535_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 14 | Q00535_RRC | RRC | DB06195 | 160355 | CHEMBL14762 | R-ROSCOVITINE | n/a | |
| 15 | Q00535_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 16 | Q00535_Z3R | Z3R | n/a | 11687981 | CHEMBL2069711 | 4-(1,3-benzothiazol-2-yl)thiophene-2-sulfonamide | n/a | |
| 17 | Q00535_OLO | OLO | DB02116 | 4592 | CHEMBL280074 | Olomoucine | inhibitor | IC50(nM) = 3000.0 |
| 18 | Q00535_HMD | HMD | DB02950 | 17754027;139031112; | n/a | Hymenialdisine | inhibitor | |
| 19 | Q00535_SU9 | SU9 | DB03428 | 5289419 | CHEMBL258805 | SU9516 | inhibitor | |
| 20 | Q00535_CPB | CPB | DB03496 | 5287969 | CHEMBL428690 | Alvocidib | n/a | IC50(nM) = 170.0 Kd(nM) = 43.0 |
| 21 | Q00535_ATU | ATU | DB04014 | 5005498 | CHEMBL50894 | Alsterpaullone | inhibitor | IC50(nM) = 40.0 |
| 22 | Q00535_DB15442 | n/a | DB15442 | n/a | n/a | Trilaciclib | inhibitor |