Q01959 SC6A3_HUMAN
Gene name: SLC6A3
Protein name: Sodium-dependent dopamine transporter

List of molecules and drugs that interact with protein Q01959

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	Q01959_DB00182	n/a	DB00182	n/a	n/a	Amphetamine	negative modulator	Ki(nM) = 24.8
2	Q01959_DB00191	n/a	DB00191	n/a	n/a	Phentermine	inhibitor
3	Q01959_CXQ	CXQ	DB00245	n/a	CHEMBL1201203	Benzatropine	inhibitor	IC50(nM) = 312.0
4	Q01959_DB00285	n/a	DB00285	n/a	n/a	Venlafaxine	inhibitor	Ki(nM) = 3070.0 IC50(nM) = 2550.0 Kd(nM) = 9300.0
5	Q01959_DB00408	n/a	DB00408	n/a	n/a	Loxapine	binder
6	Q01959_DB00422	n/a	DB00422	n/a	n/a	Methylphenidate	inhibitor	Ki(nM) = 34.0 IC50(nM) = 17.0
7	Q01959_DB00454	n/a	DB00454	n/a	n/a	Meperidine	inhibitor
8	Q01959_IXX	IXX	DB00458	3696	CHEMBL11	Imipramine	inhibitor	Ki(nM) = 8500.0 IC50(nM) = 25600.0
9	Q01959_29E	29E	DB00476	60835	CHEMBL1175	Duloxetine	inhibitor	Ki(nM) = 240.0 IC50(nM) = 590.0
10	Q01959_DB00543	n/a	DB00543	n/a	n/a	Amoxapine	binder	Ki(nM) = 4310.0
11	Q01959_DB00579	n/a	DB00579	n/a	n/a	Mazindol	inhibitor	Ki(nM) = 15.4 IC50(nM) = 13.0
12	Q01959_DB00721	n/a	DB00721	n/a	n/a	Procaine	inhibitor
13	Q01959_DB00726	n/a	DB00726	n/a	n/a	Trimipramine	inhibitor	Ki(nM) = 3780.0
14	Q01959_DB00745	n/a	DB00745	n/a	n/a	Modafinil	inhibitor	Ki(nM) = 927.0 IC50(nM) = 11500.0
15	Q01959_DB00830	n/a	DB00830	n/a	n/a	Phenmetrazine	inhibitor
16	Q01959_DB00852	n/a	DB00852	n/a	n/a	Pseudoephedrine	inhibitor
17	Q01959_DB00865	n/a	DB00865	n/a	n/a	Benzphetamine	inhibitor
18	Q01959_COC	COC	DB00907	446220	CHEMBL370805	Cocaine	inhibitor	Ki(nM) = 68.5 IC50(nM) = 267.0 EC50(nM) = 267.0
19	Q01959_DB00937	n/a	DB00937	n/a	n/a	Diethylpropion	inhibitor
20	Q01959_LDP	LDP	DB00988	681	CHEMBL59	Dopamine	inducer	Ki(nM) = 67.0 IC50(nM) = 460.0
21	Q01959_SRE	SRE	DB01104	68617	CHEMBL809	Sertraline	inhibitor	IC50(nM) = 310.0 Kd(nM) = 25.0
22	Q01959_DB01105	n/a	DB01105	n/a	n/a	Sibutramine	inhibitor
23	Q01959_DB01114	n/a	DB01114	n/a	n/a	Chlorpheniramine	inhibitor
24	Q01959_DB01146	n/a	DB01146	n/a	n/a	Diphenylpyraline	inhibitor
25	Q01959_DB01149	n/a	DB01149	n/a	n/a	Nefazodone	inhibitor	Ki(nM) = 360.0 Kd(nM) = 360.0
26	Q01959_DB01156	n/a	DB01156	n/a	n/a	Bupropion	inhibitor	Ki(nM) = 173.0 IC50(nM) = 330.0
27	Q01959_DB01161	n/a	DB01161	n/a	n/a	Chloroprocaine	inhibitor
28	Q01959_68P	68P	DB01175	146570	CHEMBL1508	Escitalopram	inhibitor
29	Q01959_9SC	9SC	DB01238	60795	CHEMBL1112	Aripiprazole	modulator	Ki(nM) = 3220.0
30	Q01959_DB01442	n/a	DB01442	n/a	n/a	MMDA	negative modulator
31	Q01959_DB01454	n/a	DB01454	n/a	n/a	Midomafetamine	negative modulator	Ki(nM) = 10000.0 IC50(nM) = 1442.0 EC50(nM) = 1000.0
32	Q01959_DB01463	n/a	DB01463	n/a	n/a	Fencamfamin	inhibitor
33	Q01959_DB01472	n/a	DB01472	n/a	n/a	4-Methoxyamphetamine	inhibitor
34	Q01959_1WE	1WE	DB01576	5826	CHEMBL612	Dextroamphetamine	negative modulator	EC50(nM) = 24.8
35	Q01959_B40	B40	DB01577	10836	CHEMBL1201201	Metamfetamine	negative modulator
36	Q01959_DB03701	n/a	DB03701	n/a	n/a	Vanoxerine	antagonist
37	Q01959_DB04821	n/a	DB04821	n/a	n/a	Nomifensine	n/a	Ki(nM) = 10.0 IC50(nM) = 15.0
38	Q01959_DB04947	n/a	DB04947	n/a	n/a	Altropane	inhibitor
39	Q01959_DB06148	n/a	DB06148	n/a	n/a	Mianserin	binder
40	Q01959_DB06156	n/a	DB06156	n/a	n/a	Tesofensine	n/a
41	Q01959_DB06333	n/a	DB06333	n/a	n/a	Trodusquemine	n/a
42	Q01959_DB06413	n/a	DB06413	n/a	n/a	Armodafinil	antagonist
43	Q01959_DB06700	n/a	DB06700	n/a	n/a	Desvenlafaxine	inhibitor	Ki(nM) = 3726.0
44	Q01959_DB06701	n/a	DB06701	n/a	n/a	Dexmethylphenidate	inhibitor	Ki(nM) = 16.0 IC50(nM) = 88.0
45	Q01959_DB12305	n/a	DB12305	n/a	n/a	Dasotraline	inhibitor
46	Q01959_DB14754	n/a	DB14754	n/a	n/a	Solriamfetol	n/a
47	Q01959_DB16629	n/a	DB16629	n/a	n/a	Serdexmethylphenidate	inhibitor