Gene name: Ptgs2
Protein name: Prostaglandin G/H synthase
List of molecules and drugs that interact with protein Q05769
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q05769_1AG | 1AG | n/a | 16019980 | CHEMBL124426 | (2S)-2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate | n/a | |
| 2 | Q05769_416 | 416 | n/a | 9858913 | CHEMBL1230209 | (2S)-7-tert-butyl-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid | n/a | |
| 3 | Q05769_4LA | 4LA | n/a | n/a | n/a | (R)-7-{[5-methoxy-2-methyl-3-(methoxycarbonylmethyl)-1H-indolyl]carbonyl}-7,8-dicarba-nido-dodeca-hydroundecaborate | n/a | |
| 4 | Q05769_52B | 52B | n/a | 9831791 | CHEMBL1230348 | (2S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid | n/a | |
| 5 | Q05769_60A | 60A | n/a | 137348416 | n/a | 2-[(2~{R})-2-(hydroxymethyloxy)propoxy]ethanol | n/a | |
| 6 | Q05769_ACD | ACD | DB04557 | 444899 | CHEMBL15594 | ARACHIDONIC ACID | n/a | |
| 7 | Q05769_AKR | AKR | DB02579 | 6581;19966351; | CHEMBL1213529 | ACRYLIC ACID | n/a | |
| 8 | Q05769_BOG | BOG | n/a | 62852 | CHEMBL446037 | octyl beta-D-glucopyranoside | n/a | |
| 9 | Q05769_CEL | CEL | DB00482 | 2662 | CHEMBL118 | 4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE | n/a | IC50(nM) = 0.51 |
| 10 | Q05769_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 11 | Q05769_COH | COH | DB02110 | n/a | n/a | PROTOPORPHYRIN IX CONTAINING CO | n/a | |
| 12 | Q05769_D72 | D72 | n/a | 46926545 | CHEMBL1232083 | (2R)-6,8-dichloro-7-(2-methylpropoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid | n/a | |
| 13 | Q05769_DF0 | DF0 | n/a | 11831237 | CHEMBL2152245 | (2-fluorobiphenyl-4-yl)acetic acid | n/a | |
| 14 | Q05769_DIF | DIF | DB00586 | 3033 | CHEMBL139 | 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID | n/a | IC50(nM) = 22.0 |
| 15 | Q05769_DXS | DXS | n/a | 24823808 | n/a | 2-[1-(4-chlorobenzene-1-carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-[2-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)ethyl]acetamide | n/a | |
| 16 | Q05769_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 17 | Q05769_EPA | EPA | DB00159 | 446284 | CHEMBL460026 | 5,8,11,14,17-EICOSAPENTAENOIC ACID | n/a | |
| 18 | Q05769_FF8 | FF8 | n/a | 117072556 | CHEMBL3774784 | (2S)-2-{2-fluoro-3'-[(hexylcarbamoyl)oxy][1,1'-biphenyl]-4-yl}propanoic acid | n/a | |
| 19 | Q05769_FLP | FLP | DB16159 | 72099 | CHEMBL435298 | FLURBIPROFEN | n/a | |
| 20 | Q05769_FLR | FLR | DB05289 | 92337 | CHEMBL190083 | (2R)-2-(3-fluoro-4-phenyl-phenyl)propanoic acid | n/a | IC50(nM) = 1300.0 |
| 21 | Q05769_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 22 | Q05769_HEM | HEM | DB18267 | n/a | n/a | PROTOPORPHYRIN IX CONTAINING FE | n/a | |
| 23 | Q05769_HXA | HXA | DB03756 | 445580 | CHEMBL367149 | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID | n/a | |
| 24 | Q05769_IBP | IBP | DB09213 | 39912 | CHEMBL175 | IBUPROFEN | n/a | |
| 25 | Q05769_ICD | ICD | DB08942 | 54677972 | CHEMBL53292 | 4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide | n/a | |
| 26 | Q05769_IMN | IMN | DB00328 | 3715 | CHEMBL6 | INDOMETHACIN | n/a | IC50(nM) = 6.4 |
| 27 | Q05769_IXP | IXP | n/a | 46880558 | CHEMBL1076638 | (5S,5aS,8aS,9S)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4-{[4-({[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}amino)butyl]amino}-4-oxobutanoate | n/a | |
| 28 | Q05769_L7M | L7M | n/a | 24824512 | n/a | 2-[1-(4-chlorobenzene-1-carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-[4-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)butyl]acetamide | n/a | |
| 29 | Q05769_LM8 | LM8 | n/a | 87057572 | n/a | (5Z,8Z,11Z,13S,14Z)-13-methylicosa-5,8,11,14-tetraenoic acid | n/a | |
| 30 | Q05769_LNL | LNL | DB00132 | 5280934 | CHEMBL8739 | ALPHA-LINOLENIC ACID | n/a | |
| 31 | Q05769_LUR | LUR | DB01283 | 151166 | CHEMBL404108 | {2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid | n/a | IC50(nM) = 40.0 |
| 32 | Q05769_MAN | MAN | n/a | 185698 | CHEMBL365590 | alpha-D-mannopyranose | n/a | |
| 33 | Q05769_MXM | MXM | DB00814 | 54677470 | CHEMBL599 | 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide | n/a | IC50(nM) = 151.0 |
| 34 | Q05769_N1B | N1B | n/a | n/a | n/a | (S)-7-{[5-methoxy-2-methyl-3-(methoxycarbonylmethyl)-1H-indolyl]carbonyl}-7,8-dicarba-nido-dodeca-hydroundecaborate | n/a | |
| 35 | Q05769_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 36 | Q05769_NPX | NPX | n/a | 169118 | CHEMBL1618254 | (2R)-2-(6-methoxynaphthalen-2-yl)propanoic acid | n/a | |
| 37 | Q05769_NS4 | NS4 | DB14060 | 4553 | CHEMBL7162 | N-[2-(cyclohexyloxy)-4-nitrophenyl]methanesulfonamide | n/a | |
| 38 | Q05769_PGX | PGX | DB03866 | 5280883 | n/a | 7-[6-(3-HYDROPEROXY-OCT-1-ENYL)-2,3-DIOXA-BICYCLO[2.2.1]HEPT-5-YL]-HEPT-5-ENOIC ACID | n/a | |
| 39 | Q05769_PLM | PLM | DB03796 | 985;135369651; | CHEMBL82293 | PALMITIC ACID | n/a | |
| 40 | Q05769_S58 | S58 | DB03477 | 1396 | CHEMBL1235806 | 1-PHENYLSULFONAMIDE-3-TRIFLUOROMETHYL-5-PARABROMOPHENYLPYRAZOLE | n/a | |
| 41 | Q05769_Y8A | Y8A | n/a | 145927371 | CHEMBL4758939 | 9-[(4-chlorophenyl)methyl]-6-methoxy-1-methyl-4,9-dihydro-3H-beta-carboline | n/a |