Gene name: BTK
Protein name: Tyrosine-protein kinase BTK
List of molecules and drugs that interact with protein Q06187
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q06187_027 | 027 | n/a | 11545405 | CHEMBL470736 | 7-(4-methylpiperazin-1-yl)-4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-(propan-2-yl)phthalazin-1(2H)-one | n/a | |
| 2 | Q06187_03C | 03C | n/a | 49835964 | n/a | [5-amino-1-(2-methylphenyl)-1H-pyrazol-4-yl]{3-[1-(methylsulfonyl)piperidin-4-yl]phenyl}methanone | n/a | |
| 3 | Q06187_04K | 04K | n/a | 20626966 | n/a | 2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-6-(4-fluorophenoxy)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one | n/a | |
| 4 | Q06187_04L | 04L | n/a | 16062971 | n/a | 2-methyl-N-(2-phenyl-3H-imidazo[4,5-b]pyridin-6-yl)-5-{[(2E)-3-phenylprop-2-enoyl]amino}benzamide | n/a | |
| 5 | Q06187_0B0 | 0B0 | n/a | 163321740 | n/a | (3R,3'R)-3-anilino-1'-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)[1,3'-bipiperidin]-2-one | n/a | |
| 6 | Q06187_0B9 | 0B9 | n/a | 67969330 | CHEMBL5205957 | (2R)-2-(3-chloro-5-fluoroanilino)-2-cyclopropyl-N-[(3R)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl]acetamide | n/a | |
| 7 | Q06187_0BG | 0BG | n/a | 163321741 | n/a | N-{2-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]ethyl}-N~2~-phenylglycinamide | n/a | |
| 8 | Q06187_0BQ | 0BQ | n/a | 156596332 | CHEMBL5079178 | 5-(1H-benzimidazol-2-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one | n/a | |
| 9 | Q06187_0CI | 0CI | n/a | 78322089;136295073; | n/a | 5-(1-{[(3S)-1-propanoylpyrrolidin-3-yl]oxy}isoquinolin-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one | n/a | |
| 10 | Q06187_0GW | 0GW | n/a | 156596333 | CHEMBL5073944 | 5-(1-ethoxyisoquinolin-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one | n/a | |
| 11 | Q06187_0UW | 0UW | n/a | 96642;135418902; | CHEMBL93815 | 5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-one | n/a | |
| 12 | Q06187_1E8 | 1E8 | DB09053 | 24821094 | CHEMBL1873475 | 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one | inhibitor | Ki(nM) = 4.8 IC50(nM) = 0.08 Kd(nM) = 0.64 EC50(nM) = 5.8 |
| 13 | Q06187_1N1 | 1N1 | DB01254 | 3062316 | CHEMBL1421 | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE | inhibitor | IC50(nM) = 1.3 Kd(nM) = 1.4 |
| 14 | Q06187_2IE | 2IE | n/a | 156613436 | n/a | 2-(4-phenoxyphenoxy)-5-[(3R)-1-(prop-2-enoyl)piperidin-3-yl]pyridine-3-carboxamide | n/a | |
| 15 | Q06187_2IJ | 2IJ | n/a | n/a | n/a | 5-{(3S)-1-[(Z)-iminomethyl]piperidin-3-yl}-2-(4-phenoxyphenoxy)pyridine-3-carboxamide | n/a | |
| 16 | Q06187_2P5 | 2P5 | n/a | 53356518 | CHEMBL3263640 | 4-tert-butyl-N-[2-methyl-3-(6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-7H-purin-2-yl)phenyl]benzamide | n/a | |
| 17 | Q06187_2V1 | 2V1 | n/a | 117072089 | n/a | 4-(methylsulfonyl)-N-[3-(8-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}imidazo[1,2-a]pyrazin-6-yl)phenyl]benzamide | n/a | |
| 18 | Q06187_2V2 | 2V2 | n/a | 25264450 | CHEMBL3665115 | 1-{5-[3-(7-tert-butyl-4-oxoquinazolin-3(4H)-yl)-2-methylphenyl]-1-methyl-2-oxo-1,2-dihydropyridin-3-yl}-3-methylurea | n/a | |
| 19 | Q06187_2V3 | 2V3 | n/a | 46909487 | CHEMBL3352876 | 6-cyclopropyl-2-[3-(5-{[5-(4-ethylpiperazin-1-yl)pyridin-2-yl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-(hydroxymethyl)phenyl]-8-fluoroisoquinolin-1(2H)-one | n/a | |
| 20 | Q06187_2VL | 2VL | n/a | 25234918 | CHEMBL2057915 | N-{3-[6-({4-[(2R)-1,4-dimethyl-3-oxopiperazin-2-yl]phenyl}amino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl]-2-methylphenyl }-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | n/a | |
| 21 | Q06187_3IS | 3IS | n/a | 152801 | CHEMBL2381491 | 5-chloranyl-1,3-dihydroindol-2-one | n/a | |
| 22 | Q06187_3OU | 3OU | n/a | 44155252 | CHEMBL4116421 | 6-(dimethylamino)-2-[2-(hydroxymethyl)-3-(1-methyl-5-{[5-(morpholin-4-ylcarbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]-3,4-dihydroisoquinolin-1(2H)-one | n/a | |
| 23 | Q06187_3OV | 3OV | n/a | 46908418 | CHEMBL3358339 | 6-(dimethylamino)-8-fluoro-2-[2-(hydroxymethyl)-3-(1-methyl-5-{[5-(morpholin-4-ylcarbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]isoquinolin-1(2H)-one | n/a | |
| 24 | Q06187_3P0 | 3P0 | n/a | 46908706 | CHEMBL3358341 | 2-{8-fluoro-2-[2-(hydroxymethyl)-3-(1-methyl-5-{[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]-1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl}-2-methylpropanenitrile | n/a | |
| 25 | Q06187_3YO | 3YO | n/a | 58540422 | CHEMBL3746293 | N-(6-fluoro-2-methyl-3-{5-[(5-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}phenyl)-1-benzothiophene-2-carboxamide | n/a | |
| 26 | Q06187_481 | 481 | n/a | 59754720 | n/a | 4-tert-butyl-N-{3-[8-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amino)imidazo[1,2-a]pyrazin-6-yl]phenyl}benzamide | n/a | |
| 27 | Q06187_4C9 | 4C9 | n/a | 137348225 | n/a | (2S)-2-({(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}carbonyl)-4,4-dimethylpentanenitrile | n/a | |
| 28 | Q06187_4IP | 4IP | DB01863 | n/a | CHEMBL23552 | INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE | inhibitor | |
| 29 | Q06187_4L6 | 4L6 | n/a | 71765510 | CHEMBL3586447 | 4-amino-8-(5-methyl-1H-indazol-6-yl)cinnoline-3-carboxamide | n/a | |
| 30 | Q06187_4PT | 4PT | n/a | n/a | n/a | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE | n/a | |
| 31 | Q06187_4RU | 4RU | n/a | 2814562 | CHEMBL449216 | 4-aminocinnoline-3-carboxamide | n/a | |
| 32 | Q06187_4RV | 4RV | n/a | 91809511 | CHEMBL3586444 | 4-amino-8-(4-methylpyridin-3-yl)cinnoline-3-carboxamide | n/a | |
| 33 | Q06187_4UQ | 4UQ | n/a | 49846389 | CHEMBL3622202 | 6-{(3R)-3-[(4-tert-butylbenzoyl)amino]piperidin-1-yl}-2-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}pyridine-3-carboxamide | n/a | |
| 34 | Q06187_4US | 4US | n/a | 91885524 | CHEMBL3621503 | 4-(2-chlorophenyl)-7-[(4-methylpiperazin-1-yl)carbonyl]-9H-carbazole-1-carboxamide | n/a | |
| 35 | Q06187_585 | 585 | DB07159 | 11213558 | CHEMBL475251 | 6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one | n/a | Kd(nM) = 190.0 |
| 36 | Q06187_5WE | 5WE | n/a | 137348408 | n/a | 4-[8-azanyl-3-[(2~{S})-1-[4-(dimethylamino)butanoyl]pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-~{N}-(1,3-thiazol-2-yl)benzamide | n/a | |
| 37 | Q06187_5WF | 5WF | n/a | 71222614 | CHEMBL4094125 | 4-[8-azanyl-3-[(3~{R})-1-(3-methyloxetan-3-yl)carbonylpiperidin-3-yl]imidazo[1,5-a]pyrazin-1-yl]-~{N}-[4-(trifluoromethyl)pyridin-2-yl]benzamide | n/a | |
| 38 | Q06187_5WH | 5WH | n/a | 71226367 | CHEMBL4103954 | 4-[8-azanyl-3-[(3~{R},6~{S})-1-cyclopropylcarbonyl-6-methyl-piperidin-3-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluoranyl-~{N}-[4-(trifluoromethyl)pyridin-2-yl]benzamide | n/a | |
| 39 | Q06187_6MV | 6MV | n/a | 121499156 | CHEMBL3977725 | 4-[2-fluoro-3-(4-oxoquinazolin-3(4H)-yl)phenyl]-7-(2-hydroxypropan-2-yl)-9H-carbazole-1-carboxamide | n/a | |
| 40 | Q06187_6XL | 6XL | n/a | 86683933 | CHEMBL5195945 | 6-~{tert}-butyl-8-fluoranyl-2-[3-(hydroxymethyl)-4-[1-methyl-6-oxidanylidene-5-(pyrimidin-4-ylamino)pyridin-3-yl]pyridin-2-yl]phthalazin-1-one | n/a | |
| 41 | Q06187_72V | 72V | n/a | 16358 | CHEMBL60569 | 1-methylindole-2,3-dione | n/a | |
| 42 | Q06187_73T | 73T | DB15291 | 86582336 | CHEMBL3900554 | 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide | inhibitor | |
| 43 | Q06187_746 | 746 | n/a | 24857323 | CHEMBL1230541 | 4-tert-butyl-N-[2-methyl-3-(4-methyl-6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide | n/a | |
| 44 | Q06187_7G6 | 7G6 | n/a | 46908026 | CHEMBL2057918 | 6-cyclopropyl-8-fluoranyl-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]-6-oxidanylidene-pyridin-3-yl]phenyl]isoquinolin-1-one | n/a | |
| 45 | Q06187_7G7 | 7G7 | n/a | 71257642 | n/a | 6-~{tert}-butyl-8-fluoranyl-2-[3-(hydroxymethyl)-4-[1-methyl-5-[[5-(1-methylpiperidin-4-yl)pyridin-2-yl]amino]-6-oxidanylidene-pyridazin-3-yl]pyridin-2-yl]phthalazin-1-one | n/a | |
| 46 | Q06187_7G8 | 7G8 | n/a | 89658869 | n/a | 4-[4-[[5-fluoranyl-4-[[3-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]phenoxy]-~{N}-methyl-pyridine-2-carboxamide | n/a | |
| 47 | Q06187_7G9 | 7G9 | n/a | 126653761 | n/a | ~{N}-[3-[[5-fluoranyl-2-[[4-(2-methoxyethoxy)phenyl]amino]pyrimidin-4-yl]amino]phenyl]propanamide | n/a | |
| 48 | Q06187_7GB | 7GB | n/a | 89455287 | n/a | 6-azanyl-9-[(3~{R})-1-[(~{E})-but-2-enoyl]pyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one | n/a | |
| 49 | Q06187_83P | 83P | n/a | 71656932 | CHEMBL4850816 | (R)-N-methyl-2-(3-((quinoxalin-6-ylamino)methyl)furan-2-carbonyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide | n/a | |
| 50 | Q06187_8E8 | 8E8 | n/a | 73441661 | CHEMBL3747532 | 1-[(3~{R})-3-[4-azanyl-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one | n/a | |
| 51 | Q06187_9AJ | 9AJ | DB14785 | 86567195 | CHEMBL4065122 | 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one | inhibitor | |
| 52 | Q06187_9B1 | 9B1 | n/a | 54596723 | CHEMBL3670082 | 2-[2-(hydroxymethyl)-3-{1-methyl-6-oxo-5-[(pyrimidin-4-yl)amino]-1,6-dihydropyridin-3-yl}phenyl]-6,6-dimethyl-3,4,6,7-tetrahydro-2H-cyclopenta[4,5]thieno[2,3-c]pyridin-1(5H)-one | n/a | |
| 53 | Q06187_9M3 | 9M3 | n/a | 71721544 | CHEMBL4209148 | N-[3-(4-amino-6-{[4-(morpholine-4-carbonyl)phenyl]amino}-1,3,5-triazin-2-yl)-2-methylphenyl]-4-tert-butylbenzamide | n/a | |
| 54 | Q06187_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 55 | Q06187_B43 | B43 | n/a | 6603792 | CHEMBL47940 | 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane | n/a | |
| 56 | Q06187_BA0 | BA0 | n/a | 145945979 | n/a | (7S)-2-(4-phenoxyphenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide | n/a | |
| 57 | Q06187_BME | BME | DB03345 | 1567 | CHEMBL254951 | BETA-MERCAPTOETHANOL | n/a | |
| 58 | Q06187_BNB | BNB | n/a | 134812703 | n/a | N-[2-methyl-3-[4-methyl-6-[4-(4-methylpiperazine-1-carbonyl)anilino]-5-oxo-pyrazin-2-yl]phenyl]-4-(1-piperidyl)benzamide | n/a | |
| 59 | Q06187_BTB | BTB | n/a | 81462 | n/a | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 60 | Q06187_BXJ | BXJ | n/a | 137349035 | n/a | N-{3-[(2R)-6-{[3-amino-4-(morpholine-4-carbonyl)phenyl]amino}-5-oxo-2,5-dihydropyrazin-2-yl]-2-methylphenyl}-4-(piperidin-1-yl)benzamide | n/a | |
| 61 | Q06187_BXM | BXM | n/a | 46894109 | CHEMBL1973138 | 4-tert-butyl-N-[2-methyl-3-(1-methyl-5-{[5-(morpholine-4-carbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]benzamide | n/a | |
| 62 | Q06187_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 63 | Q06187_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 64 | Q06187_DTJ | DTJ | n/a | 67995847 | n/a | 4-tert-butyl-N-[2-(hydroxymethyl)-3-(1-methyl-5-{[5-(morpholine-4-carbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridazin-3-yl)phenyl]benzamide | n/a | |
| 65 | Q06187_DTT | DTT | DB04447 | 439196 | CHEMBL406270 | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | n/a | |
| 66 | Q06187_DVD | DVD | n/a | 58540133 | n/a | N-[2-(hydroxymethyl)-3-{5-[(5-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}phenyl]-1-benzothiophene-2-carboxamide | n/a | |
| 67 | Q06187_DVJ | DVJ | n/a | 46223982 | n/a | N-[2-(2-hydroxyethyl)-3-{5-[(5-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}phenyl]-1-benzothiophene-2-carboxamide | n/a | |
| 68 | Q06187_DXM | DXM | n/a | 58540016 | n/a | N-(3-{5-[(1,5-dimethyl-1H-pyrazol-3-yl)amino]-1-methyl-6-oxo-1,6-dihydropyridazin-3-yl}-2,6-difluorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | n/a | |
| 69 | Q06187_DY4 | DY4 | n/a | 58540191 | n/a | N-(3-{5-[(1,5-dimethyl-1H-pyrazol-3-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}-2,6-difluorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | n/a | |
| 70 | Q06187_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 71 | Q06187_FPZ | FPZ | n/a | 11776 | CHEMBL1448331 | triphenylphosphane | n/a | |
| 72 | Q06187_GJ7 | GJ7 | n/a | 137349433 | n/a | 2-(4-phenoxyphenoxy)-6-[(1S,4S)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]pyridine-3-carboxamide | n/a | |
| 73 | Q06187_GJA | GJA | n/a | 118038535 | CHEMBL4241920 | 6-[(3S)-3-(acryloylamino)pyrrolidin-1-yl]-2-(4-phenoxyphenoxy)pyridine-3-carboxamide | n/a | |
| 74 | Q06187_GJD | GJD | n/a | 137349434 | n/a | 4-amino-2-[(3S)-3-(propanoylamino)pyrrolidin-1-yl]pyrimidine-5-carboxamide | n/a | |
| 75 | Q06187_GJG | GJG | n/a | 3031415 | CHEMBL4279288 | 6-(cyclohexylamino)pyridine-3-carboxamide | n/a | |
| 76 | Q06187_GJJ | GJJ | n/a | 137349435 | CHEMBL4290066 | 6-[(3S)-3-(acryloylamino)pyrrolidin-1-yl]-2-{[4-(tert-butylcarbamoyl)phenyl]amino}pyridine-3-carboxamide | n/a | |
| 77 | Q06187_GMQ | GMQ | n/a | 56656450 | CHEMBL4117175 | 6-~{tert}-butyl-8-fluoranyl-2-[2-(hydroxymethyl)-3-[1-methyl-5-[(5-morpholin-4-ylcarbonylpyridin-2-yl)amino]-6-oxidanylidene-pyridazin-3-yl]phenyl]phthalazin-1-one | n/a | |
| 78 | Q06187_GMW | GMW | n/a | 78318226 | CHEMBL4468226 | (9~{S})-12-(6-~{tert}-butyl-8-fluoranyl-1-oxidanylidene-phthalazin-2-yl)-6-methyl-4-[(5-morpholin-4-ylcarbonylpyridin-2-yl)amino]-9-oxidanyl-6-azatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2(7),3,11,13-pentaen-5-one | n/a | |
| 79 | Q06187_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 80 | Q06187_GYL | GYL | n/a | 137349470 | n/a | N-[3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-1H-1,2,4-triazol-3-yl)phenyl]propanamide | n/a | |
| 81 | Q06187_HRA | HRA | DB18866 | 129045720 | CHEMBL4756476 | 1,5-anhydro-2-{[5-(2-chloro-4-phenoxybenzene-1-carbonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}-2,3,4-trideoxy-D-erythro-hexitol | inhibitor | |
| 82 | Q06187_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 83 | Q06187_IPA | IPA | DB02325 | 3776 | CHEMBL582 | ISOPROPYL ALCOHOL | n/a | |
| 84 | Q06187_IS4 | IS4 | n/a | 168451649 | n/a | (7~{S})-2-(4-bromanyl-3,5-dimethoxy-phenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide | n/a | |
| 85 | Q06187_IS7 | IS7 | n/a | 14918455 | CHEMBL4537338 | 1,5-dimethyl-3~{H}-indol-2-one | n/a | |
| 86 | Q06187_KHD | KHD | n/a | 137349648 | n/a | N-(3-{[2-amino-3-(4-phenoxyphenyl)pyridin-4-yl]oxy}phenyl)propanamide | n/a | |
| 87 | Q06187_KLM | KLM | n/a | 137530106 | n/a | 8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[(2S)-3-(dimethylamino)-2-hydroxypropoxy]phenyl}amino)-5,8-dihydropteridine-6,7-dione | n/a | |
| 88 | Q06187_KLP | KLP | n/a | 138753298 | n/a | N-(3-{[(2,6-dimethylphenyl)methyl]amino}-7-methoxyindeno[1,2-c]pyrazol-6-yl)methanesulfonamide | n/a | |
| 89 | Q06187_L0Z | L0Z | n/a | 72201774 | CHEMBL4566818 | 4-~{tert}-butyl-~{N}-[2-methyl-3-[6-[4-(4-methylpiperazin-1-yl)carbonylphenyl]-7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl]phenyl]benzamide | n/a | |
| 90 | Q06187_L9S | L9S | n/a | 138393376 | CHEMBL4564973 | N-[2-fluoro-6-(pyrrolidin-1-yl)phenyl]-N'-{3-[(2R)-1-(2-hydroxyethyl)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-2-yl]phenyl}urea | n/a | |
| 91 | Q06187_LHL | LHL | n/a | 22125070 | CHEMBL1234002 | 3-(2,6-dichlorophenyl)-7-({4-[2-(diethylamino)ethoxy]phenyl}amino)-1-methyl-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one | n/a | |
| 92 | Q06187_LTJ | LTJ | n/a | 138753315 | n/a | 4-[(3S)-3-{[(2E)-but-2-enoyl]amino}piperidin-1-yl]-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide | n/a | |
| 93 | Q06187_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 94 | Q06187_MZJ | MZJ | DB15170 | 71479709 | CHEMBL4072833 | 1-[4-({[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino}methyl)piperidin-1-yl]prop-2-en-1-one | inhibitor | |
| 95 | Q06187_N42 | N42 | n/a | 129896681 | CHEMBL4077123 | N-[3-(5-{[3-(acryloylamino)-4-(morpholine-4-carbonyl)phenyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl]-4-tert-butylbenzamide | n/a | |
| 96 | Q06187_N6Z | N6Z | n/a | 141478757 | CHEMBL4468719 | ~{N}-[3-[6-azanyl-5-[2-[methyl(propanoyl)amino]ethoxy]pyrimidin-4-yl]-5-fluoranyl-2-methyl-phenyl]-4-cyclopropyl-2-fluoranyl-benzamide | n/a | |
| 97 | Q06187_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 98 | Q06187_NXT | NXT | n/a | 21185192 | n/a | 4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid | n/a | |
| 99 | Q06187_NYQ | NYQ | n/a | 611193 | n/a | 5-bromanyl-1,3-dihydroindol-2-one | n/a | |
| 100 | Q06187_PD | PD | n/a | 105144 | n/a | PALLADIUM ION | n/a | |
| 101 | Q06187_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 102 | Q06187_PG0 | PG0 | n/a | 8134 | CHEMBL1235250 | 2-(2-METHOXYETHOXY)ETHANOL | n/a | |
| 103 | Q06187_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 104 | Q06187_PGO | PGO | DB04349 | 439846 | n/a | S-1,2-PROPANEDIOL | n/a | |
| 105 | Q06187_Q1B | Q1B | n/a | 25307163 | n/a | 5-(trifluoromethyloxy)-1,3-dihydroindol-2-one | n/a | |
| 106 | Q06187_R1L | R1L | DB17709 | 73388818 | CHEMBL3702854 | (2E)-2-{(3R)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl}-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile | n/a | |
| 107 | Q06187_RQS | RQS | n/a | 155289261 | CHEMBL4789778 | N-{[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]methyl}benzamide | n/a | |
| 108 | Q06187_S5M | S5M | n/a | 74221357 | CHEMBL4755663 | 4-~{tert}-butyl-~{N}-[[4-(7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]methyl]benzamide | n/a | |
| 109 | Q06187_S9A | S9A | n/a | 118139356 | CHEMBL4744041 | ~{N}-[[2-methyl-4-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]methyl]-3-propan-2-yloxy-azetidine-1-carboxamide | n/a | |
| 110 | Q06187_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 111 | Q06187_TKY | TKY | n/a | 154585685 | n/a | 14-{[(3S)-2-(N-methyl-L-alanyl-3-methyl-L-valyl)-3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}-3,6,9,12-tetraoxatetradecan-1-yl (3R)-3-{5-amino-4-carbamoyl-3-[4-(2,4-difluorophenoxy)phenyl]-1H-pyrazol-1-yl}piperidine-1-carboxylate | n/a | |
| 112 | Q06187_TL7 | TL7 | n/a | 154585681 | n/a | [5-({[(3S)-2-(N-methyl-L-alanyl-3-methyl-L-valyl)-3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}methyl)pyrazin-2-yl]methyl (3R)-3-{5-amino-4-carbamoyl-3-[4-(2,4-difluorophenoxy)phenyl]-1H-pyrazol-1-yl}piperidine-1-carboxylate | n/a | |
| 113 | Q06187_TOO | TOO | n/a | n/a | n/a | (4S)-4-[2-(2-{4-[(2E)-4-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}-4-oxobut-2-en-1-yl]piperazin-1-yl}ethoxy)acetamido]-1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-L-prolinamide bound form | n/a | |
| 114 | Q06187_UB6 | UB6 | n/a | 165430677 | n/a | (5P)-5-[4-methyl-6-(2-methylpropyl)pyridin-3-yl]-4-oxo-N-[(1R,2S)-2-propanamidocyclopentyl]-4,5-dihydro-3H-1-thia-3,5,8-triazaacenaphthylene-2-carboxamide | n/a | |
| 115 | Q06187_ULV | ULV | n/a | 90282962 | CHEMBL4749037 | 4-{8-amino-3-[(6R,8aS)-3-oxohexahydro-3H-[1,3]oxazolo[3,4-a]pyridin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-N-[4-(trifluoromethyl)pyridin-2-yl]benzamide | n/a | |
| 116 | Q06187_ULY | ULY | n/a | 76902376 | CHEMBL4114929 | 4-{8-amino-3-[(6R,8aS)-3-oxo-3,5,6,7,8,8a-hexahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-methoxy-N-[4-(trifluoromethyl)pyridin-2-yl]benzamide | n/a | |
| 117 | Q06187_UM4 | UM4 | n/a | 90283326 | CHEMBL4107779 | 4-{8-amino-3-[(6R,8aS)-3-oxooctahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-(cyclopropyloxy)-N-[4-(trifluoromethyl)pyridin-2-yl]benzamide | n/a | |
| 118 | Q06187_V1G | V1G | n/a | 90646107 | CHEMBL4634904 | (1S,2S)-N-[2'-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-3'-(hydroxymethyl)-1-methyl-6-oxo[1,6-dihydro[3,4'-bipyridine]]-5-yl]-2-fluorocyclopropane-1-carboxamide | n/a | |
| 119 | Q06187_WKC | WKC | n/a | 118114824 | n/a | 5-[(3R)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | n/a | |
| 120 | Q06187_X9J | X9J | n/a | 121249896 | CHEMBL4850235 | 3-tert-butyl-N-({2-fluoro-4-[2-(1-methyl-1H-pyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]phenyl}methyl)-1,2,4-oxadiazole-5-carboxamide | n/a | |
| 121 | Q06187_X9M | X9M | n/a | 121249908 | CHEMBL4872106 | 4-tert-butyl-N-(2-methyl-3-{2-[4-(morpholine-4-carbonyl)phenyl]-1H-imidazo[4,5-b]pyridin-7-yl}phenyl)benzamide | n/a | |
| 122 | Q06187_X9P | X9P | n/a | 146437264 | CHEMBL4857459 | 3-tert-butyl-N-[(1S)-6-{2-[5-methyl-1-(propan-2-yl)-1H-pyrazol-4-yl]-1H-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | n/a | |
| 123 | Q06187_X9S | X9S | n/a | 146437414 | CHEMBL4876326 | 3-tert-butyl-N-[(1R)-6-{2-[5-methyl-1-(oxan-4-yl)-1H-pyrazol-4-yl]-3H-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | n/a | |
| 124 | Q06187_X9V | X9V | n/a | 146437256 | CHEMBL4872092 | 3-tert-butyl-N-[(1S)-6-{2-[3-methyl-1-(oxan-4-yl)-1H-pyrazol-4-yl]-1H-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | n/a | |
| 125 | Q06187_X9Y | X9Y | n/a | 146437124 | CHEMBL4877846 | 3-tert-butyl-N-[(5R)-2-{2-[3,5-dimethyl-1-(propan-2-yl)-1H-pyrazol-4-yl]-3H-imidazo[4,5-b]pyridin-7-yl}-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]-1,2,4-oxadiazole-5-carboxamide | n/a | |
| 126 | Q06187_Y7W | Y7W | DB17472 | 129269915 | CHEMBL4650485 | pirtobrutinib | inhibitor | |
| 127 | Q06187_Y8C | Y8C | n/a | 68064155 | n/a | N~2~-(3-chlorophenyl)-N-[(3R)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl]glycinamide | n/a | |
| 128 | Q06187_Y8H | Y8H | n/a | 166625102 | n/a | 2-(3,5-dichloroanilino)-1-{(3R)-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]azepan-1-yl}ethan-1-one | n/a | |
| 129 | Q06187_YD7 | YD7 | n/a | 118139372 | CHEMBL5090290 | ~{N}-[(5~{R})-2-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{H}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide | n/a | |
| 130 | Q06187_YDA | YDA | n/a | 135355941 | CHEMBL5083772 | 1-~{tert}-butyl-~{N}-[(5~{R})-8-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-2-(oxetan-3-yl)-1,3,4,5-tetrahydro-2-benzazepin-5-yl]-1,2,3-triazole-4-carboxamide | n/a | |
| 131 | Q06187_ZB9 | ZB9 | n/a | 86706444 | CHEMBL5276931 | 2-(3,5-dichloroanilino)-1-{(3R)-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}ethan-1-one | n/a | |
| 132 | Q06187_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 133 | Q06187_DB11703 | n/a | DB11703 | n/a | n/a | Acalabrutinib | inhibitor | |
| 134 | Q06187_DB11764 | n/a | DB11764 | n/a | n/a | Spebrutinib | inhibitor | |
| 135 | Q06187_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
| 136 | Q06187_DB15035 | n/a | DB15035 | n/a | n/a | Zanubrutinib | inhibitor | |
| 137 | Q06187_DB15227 | n/a | DB15227 | n/a | n/a | Tirabrutinib | inhibitor | |
| 138 | Q06187_DB15327 | n/a | DB15327 | n/a | n/a | Abivertinib | inhibitor | |
| 139 | Q06187_DB15347 | n/a | DB15347 | n/a | n/a | Branebrutinib | inhibitor | |
| 140 | Q06187_DB16657 | n/a | DB16657 | n/a | n/a | Vecabrutinib | inhibitor |