Gene name: BCL2L1
Protein name: Bcl-2-like protein 1
List of molecules and drugs that interact with protein Q07817
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q07817_03B | 03B | n/a | 60169704 | CHEMBL2159737 | 5-(4-chlorophenyl)-4-{3-[4-(4-{[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrophenyl)sulfonyl]amino}phenyl)piperazin-1-yl]phenyl}-1,2-dimethyl-1H-pyrrole-3-carboxylic acid | n/a | |
| 2 | Q07817_0Q5 | 0Q5 | n/a | 56973540 | CHEMBL2030861 | 4-[5-butyl-3-(hydroxymethyl)-1-phenyl-1H-pyrazol-4-yl]-3-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)-N-{[2-(trimethylsilyl)ethyl]sulfonyl}benzamide | n/a | |
| 3 | Q07817_33B | 33B | n/a | n/a | n/a | 3,3'-(E)-diazene-1,2-diylbis{6-[(chloroacetyl)amino]benzenesulfonic acid} | n/a | |
| 4 | Q07817_38H | 38H | n/a | 46836862 | CHEMBL3342192 | 2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl]-5-{3-[4-(1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenoxy]propyl}-1,3-thiazole-4-carboxylic acid | n/a | |
| 5 | Q07817_3CQ | 3CQ | n/a | 59447577 | CHEMBL3342332 | 2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl]-5-(3-{4-[3-(dimethylamino)prop-1-yn-1-yl]-2-fluorophenoxy}propyl)-1,3-thiazole-4-carboxylic acid | n/a | |
| 6 | Q07817_43B | 43B | n/a | 4369510 | CHEMBL1230221 | 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE | n/a | |
| 7 | Q07817_4FC | 4FC | DB07108 | 2782689 | CHEMBL106708 | 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID | inhibitor | IC50(nM) = 99200.0 Kd(nM) = 300000.0 EC50(nM) = 31500.0 |
| 8 | Q07817_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 9 | Q07817_B50 | B50 | n/a | 57339126 | CHEMBL2063880 | 4-(4-chlorophenyl)-1-[(3S)-3,4-dihydroxybutyl]-N-[3-(4-methylpiperazin-1-yl)propyl]-3-phenyl-1H-pyrrole-2-carboxamide | n/a | |
| 10 | Q07817_BCT | BCT | n/a | 769;22647601; | n/a | BICARBONATE ION | n/a | |
| 11 | Q07817_BR | BR | n/a | 259 | n/a | BROMIDE ION | n/a | |
| 12 | Q07817_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 13 | Q07817_CD | CD | n/a | 31193 | n/a | CADMIUM ION | n/a | |
| 14 | Q07817_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 15 | Q07817_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 16 | Q07817_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 17 | Q07817_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 18 | Q07817_H0Y | H0Y | n/a | 59438327 | CHEMBL3287282 | 6-[(8E)-8-(1,3-benzothiazol-2-ylhydrazinylidene)-6,7-dihydro-5H-naphthalen-2-yl]pyridine-2-carboxylic acid | n/a | |
| 19 | Q07817_H1I | H1I | n/a | 71297208 | CHEMBL3400496 | N-(3-(5-(1-(2-(benzo[d]thiazol-2-yl)hydrazono)ethyl)furan-2-yl)phenylsulfonyl)-6-phenylhexanamide | n/a | |
| 20 | Q07817_HI0 | HI0 | n/a | 24798804 | CHEMBL1689139 | (R)-N-(7-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)quinazolin-4-yl)-4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrobenzenesulfonamide | n/a | |
| 21 | Q07817_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 22 | Q07817_IOD | IOD | n/a | 30165 | n/a | IODIDE ION | n/a | |
| 23 | Q07817_JFF | JFF | n/a | n/a | n/a | (2R)-3-[2-(aminomethyl)-3-azanyl-1-[4-[2-(2-chloranylethanoylamino)ethylcarbamoyl]phenyl]prop-1-enyl]sulfanyl-2-(carboxyamino)propanoic acid | n/a | |
| 24 | Q07817_JJ9 | JJ9 | n/a | 169452746 | n/a | N-(2-acetamidoethyl)-4-(4-methanoyl-1,3-thiazol-2-yl)benzamide | n/a | |
| 25 | Q07817_KBH | KBH | n/a | 145946042 | CHEMBL4524407 | 4-(4-fluorophenyl)-3-fluorosulfonyl-benzoic acid | n/a | |
| 26 | Q07817_LC6 | LC6 | n/a | 72793176 | CHEMBL3126119 | 7-(4-{[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrophenyl)sulfonyl]carbamoyl}-2-methylphenyl)-3-[3-(naphthalen-1-yloxy)propyl]pyrazolo[1,5-a]pyridine-2-carboxylic acid | n/a | |
| 27 | Q07817_LI0 | LI0 | n/a | 15991563 | CHEMBL218222 | 4-(4-BENZYL-4-METHOXYPIPERIDIN-1-YL)-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE | n/a | |
| 28 | Q07817_LIW | LIW | n/a | 15991564 | CHEMBL218223 | 4-[4-(BIPHENYL-2-YLMETHYL)PIPERAZIN-1-YL]-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE | n/a | |
| 29 | Q07817_N3B | N3B | n/a | 4369509 | CHEMBL371861 | N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITRO-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE | n/a | |
| 30 | Q07817_N3C | N3C | DB17023 | 11228183 | CHEMBL376408 | 4-{4-[(4'-CHLOROBIPHENYL-2-YL)METHYL]PIPERAZIN-1-YL}-N-{[4-({(1R)-3-(DIMETHYLAMINO)-1-[(PHENYLTHIO)METHYL]PROPYL}AMINO)-3-NITROPHENYL]SULFONYL}BENZAMIDE | n/a | |
| 31 | Q07817_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 32 | Q07817_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 33 | Q07817_QHJ | QHJ | n/a | 155907147 | CHEMBL5085781 | (R)-2-(3-(2-((4'-Chloro-[1,1'-biphenyl]-2-yl)methyl)-1,2,3,4-tetrahydroisoquinoline-6-carbonyl)-3-(4-methylbenzyl)ureido)-3-((cyclohexylmethyl)sulfonyl)propanoic acid | n/a | |
| 34 | Q07817_QHP | QHP | n/a | n/a | n/a | (R)-2-(3-([1,1'-Biphenyl]-4-carbonyl)-3-(4-methylbenzyl)ureido)-3-(((3R,5R,7R)-adamantan-1-ylmethyl)sulfonyl)propanoic acid | n/a | |
| 35 | Q07817_QHS | QHS | n/a | 155907145 | CHEMBL5080415 | (R)-2-(3-([1,1'-Biphenyl]-4-carbonyl)-3-(4-methylbenzyl)ureido)-3-((cyclohexylmethyl)sulfonyl)propanoic acid | n/a | |
| 36 | Q07817_QHV | QHV | n/a | 155907144 | CHEMBL5090500 | (R)-3-(Benzylthio)-2-(3-(4-chloro-[1,1':2',1'':3'',1'''-quaterphenyl]-4'''-carbonyl)-3-(4-methylbenzyl)ureido)propanoic acid | n/a | |
| 37 | Q07817_QL8 | QL8 | n/a | 154571996 | CHEMBL5205953 | 2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]-5-[3-[4-[3-[2-[2-[2-[2-[2-[3-[[(2~{S})-3,3-dimethyl-1-[(2~{S},4~{R})-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-1-oxidanylidene-butan-2-yl]amino]-3-oxidanylidene-propoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]prop-1-ynyl]phenoxy]propyl]-1,3-thiazole-4-carboxylic acid | n/a | |
| 38 | Q07817_RQ7 | RQ7 | n/a | 71553299 | CHEMBL3910958 | 6-{8-[(1,3-benzothiazol-2-yl)carbamoyl]-3,4-dihydroisoquinolin-2(1H)-yl}-3-{1-[(pyridin-4-yl)methyl]-1H-pyrazol-4-yl}pyridine-2-carboxylic acid | n/a | |
| 39 | Q07817_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 40 | Q07817_TN1 | TN1 | n/a | 68258 | CHEMBL449132 | 5,6,7,8-TETRAHYDRONAPHTHALEN-1-OL | n/a | |
| 41 | Q07817_V9S | V9S | n/a | 155804564 | n/a | 6-[(8E)-8-{2-[4-(benzylcarbamoyl)-1,3-thiazol-2-yl]hydrazinylidene}-5,6,7,8-tetrahydronaphthalen-2-yl]-3-(2-phenylethoxy)pyridine-2-carboxylic acid | n/a | |
| 42 | Q07817_X0B | X0B | n/a | 71297207 | CHEMBL3342187 | 5-[3-[4-(aminomethyl)phenoxy]propyl]-2-[(8E)-8-(1,3-benzothiazol-2-ylhydrazinylidene)-6,7-dihydro-5H-naphthalen-2-yl]-1,3-thiazole-4-carboxylic acid | n/a | |
| 43 | Q07817_X0D | X0D | n/a | 72715983 | CHEMBL3125475 | (R)-2-(3-(3-((2,4-DIFLUOROPENYL)ETHYNYL)BENZOYL)-3-PROPYLUREIDO)-3-(ISOBUTYLTHIO) PROPANOIC ACID | n/a | |
| 44 | Q07817_X0J | X0J | n/a | 44182311 | CHEMBL1236741 | 4-[4-(biphenyl-3-ylmethyl)piperazin-1-yl]-N-{[4-({(1R)-3-(dimethylamino)-1-[(phenylsulfanyl)methyl]propyl}amino)-3-nitrophenyl]sulfonyl}benzamide | n/a | |
| 45 | Q07817_X0R | X0R | n/a | 72715984 | CHEMBL3125476 | (R)-3-(4-BROMOBENZYLTHIO)-2-(3-(3-((2,4-DIFLUOROPHENYL)ETHYNYL)BENZOYL)-3-PROPYLUREIDO)PROPANOIC ACID | n/a | |
| 46 | Q07817_X8U | X8U | n/a | 71297203 | CHEMBL3400497 | 2-[(8E)-8-(1,3-benzothiazol-2-ylhydrazinylidene)-6,7-dihydro-5H-naphthalen-2-yl]-5-(4-phenylbutyl)-1,3-thiazole-4-carboxylic acid | n/a | |
| 47 | Q07817_XOU | XOU | n/a | 24968271 | CHEMBL5077486 | (2R)-3-(Benzylsulfanyl)-2-({[(4-methylphenyl)methyl] [(4 phenylphenyl)carbonyl] carbamoyl}amino) propanoic acid | n/a | |
| 48 | Q07817_XOY | XOY | n/a | 155907143 | CHEMBL5085156 | (R)-3-(Benzylthio)-2-(3-(2-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)-1,2,3,4-tetrahydroisoquinoline-6-carbonyl)-3-(4-methylbenzyl)ureido)propanoic acid | n/a | |
| 49 | Q07817_XZM | XZM | n/a | 73295742 | CHEMBL3699067 | N-(1,3-benzothiazol-2-yl)-2-(4-{[(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]carbamoyl}-1,3-thiazol-2-yl)-1,2,3,4-tetrahydroisoquinoline-8-carboxamide | n/a | |
| 50 | Q07817_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 51 | Q07817_DB13044 | n/a | DB13044 | n/a | n/a | Gossypol | n/a |