Gene name: PPARA
Protein name: Peroxisome proliferator-activated receptor
List of molecules and drugs that interact with protein Q07869
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q07869_13M | 13M | n/a | 25112371 | CHEMBL1956149 | (2S)-2-(4-methoxy-3-{[(pyren-1-ylcarbonyl)amino]methyl}benzyl)butanoic acid | n/a | |
| 2 | Q07869_2VN | 2VN | n/a | 3392731 | CHEMBL21241 | 2-[(4-{2-[(4-cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid | n/a | |
| 3 | Q07869_471 | 471 | n/a | 446738 | CHEMBL500272 | N-((2S)-2-({(1Z)-1-METHYL-3-OXO-3-[4-(TRIFLUOROMETHYL) PHENYL]PROP-1-ENYL}AMINO)-3-{4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL}PROPYL)PROPANAMIDE | n/a | |
| 4 | Q07869_4M5 | 4M5 | n/a | 137348263 | n/a | (4~{Z},7~{Z},10~{Z},13~{Z},19~{Z})-17-oxidanylidenedocosa-4,7,10,13,19-pentaenoic acid | n/a | |
| 5 | Q07869_544 | 544 | n/a | 446642 | CHEMBL410478 | 2-(1-METHYL-3-OXO-3-PHENYL-PROPYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID | n/a | |
| 6 | Q07869_65W | 65W | n/a | 327338 | CHEMBL1600564 | 2-methyl-2-[4-(naphthalen-1-yl)phenoxy]propanoic acid | n/a | |
| 7 | Q07869_735 | 735 | DB07215 | 9956726 | CHEMBL219586 | 2-METHYL-2-(4-{[({4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL}CARBONYL)AMINO]METHYL}PHENOXY)PROPANOIC ACID | n/a | Kd(nM) = 170.0 EC50(nM) = 4.0 |
| 8 | Q07869_7HA | 7HA | n/a | 16725047 | CHEMBL1089501 | N-(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy}benzyl)-N-(methoxycarbonyl)glycine | n/a | |
| 9 | Q07869_ACD | ACD | DB04557 | 444899 | CHEMBL15594 | ARACHIDONIC ACID | n/a | |
| 10 | Q07869_AZ2 | AZ2 | DB06536 | 208901 | CHEMBL282686 | (2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL}ETHOXY)PHENYL]PROPANOIC ACID | modulator | |
| 11 | Q07869_BJB | BJB | DB14801 | 68677842 | CHEMBL4091374 | 4-[1-(1,3-benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl]butanoic acid | agonist | |
| 12 | Q07869_C5F | C5F | n/a | 6603766 | CHEMBL1317234 | 2-{4-[(1S)-2,2-dichlorocyclopropyl]phenoxy}-2-methylpropanoic acid | n/a | |
| 13 | Q07869_CPQ | CPQ | DB01890 | 446320 | n/a | N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE | inhibitor | |
| 14 | Q07869_CTM | CTM | n/a | 10342734 | n/a | (2S)-3-(4-{[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methoxy}-2-methylphenyl)-2-ethoxypropanoic acid | n/a | |
| 15 | Q07869_E0O | E0O | n/a | 2797 | CHEMBL683 | 2-(4-chloranylphenoxy)-2-methyl-propanoic acid | n/a | |
| 16 | Q07869_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 17 | Q07869_EPA | EPA | DB00159 | 446284 | CHEMBL460026 | 5,8,11,14,17-EICOSAPENTAENOIC ACID | n/a | IC50(nM) = 1100.0 |
| 18 | Q07869_ET1 | ET1 | DB07724 | 11395145 | CHEMBL1232583 | 3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid | agonist | |
| 19 | Q07869_EWR | EWR | DB13115 | 60151560 | CHEMBL4297530 | (2S)-2-ethoxy-3-[4-[2-[2-methyl-5-(4-methylsulfanylphenyl)pyrrol-1-yl]ethoxy]phenyl]propanoic acid | n/a | |
| 20 | Q07869_F5A | F5A | DB13873 | 64929 | CHEMBL981 | 2-[4-(4-chlorobenzene-1-carbonyl)phenoxy]-2-methylpropanoic acid | agonist | |
| 21 | Q07869_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 22 | Q07869_GW9 | GW9 | DB07863 | 644213 | CHEMBL375270 | 2-chloro-5-nitro-N-phenylbenzamide | n/a | |
| 23 | Q07869_HVX | HVX | n/a | 156612864 | n/a | (2S)-2-[[4-butoxy-3-[(pyren-1-ylcarbonylamino)methyl]phenyl]methyl]butanoic acid | n/a | |
| 24 | Q07869_HW3 | HW3 | n/a | 156612865 | n/a | (2S)-2-[[3-[[3-fluoranyl-4-(4-fluoranylphenoxy)phenyl]methylcarbamoyl]-4-methoxy-phenyl]methyl]butanoic acid | n/a | |
| 25 | Q07869_IL2 | IL2 | n/a | 51397006 | n/a | (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S,4R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]hexahydropentalen-2(1H)-ylidene]pentanoic acid | n/a | |
| 26 | Q07869_ITY | ITY | n/a | 1780 | CHEMBL458328 | icosa-5,8,11,14-tetraynoic acid | n/a | |
| 27 | Q07869_KKB | KKB | DB12390 | 11236126 | CHEMBL230158 | Seladelpar | n/a | |
| 28 | Q07869_MMB | MMB | n/a | 16758209 | n/a | (2R,3E)-2-{4-[(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)METHOXY]BENZYL}-3-(PROPOXYIMINO)BUTANOIC ACID | n/a | |
| 29 | Q07869_MUO | MUO | DB05187 | 9864881 | CHEMBL3707395 | 2-[2,6-dimethyl-4-[(~{E})-3-(4-methylsulfanylphenyl)-3-oxidanylidene-prop-1-enyl]phenoxy]-2-methyl-propanoic acid | agonist | |
| 30 | Q07869_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 31 | Q07869_NKS | NKS | n/a | 45254002 | CHEMBL1089210 | N-(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy}benzyl)-N-[(4-methylphenoxy)carbonyl]glycine | n/a | |
| 32 | Q07869_OLA | OLA | n/a | 445639 | CHEMBL8659 | OLEIC ACID | n/a | |
| 33 | Q07869_P7F | P7F | DB15212 | 11526038 | CHEMBL247951 | (2~{R})-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid | agonist | |
| 34 | Q07869_PEM | PEM | DB01393 | 39042 | CHEMBL264374 | 2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID | agonist | EC50(nM) = 30000.0 |
| 35 | Q07869_PLM | PLM | DB03796 | 985;135369651; | CHEMBL82293 | PALMITIC ACID | n/a | IC50(nM) = 1500.0 EC50(nM) = 35000.0 |
| 36 | Q07869_REW | REW | n/a | 10391684 | CHEMBL271240 | (2S,3S)-1-(4-METHOXYPHENYL)-3-(3-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)BENZYL)-4-OXOAZETIDINE-2-CARBOXYLIC ACID | n/a | |
| 37 | Q07869_RO7 | RO7 | DB08915 | 10274777 | CHEMBL519504 | (2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}propanoic acid | agonist | IC50(nM) = 38.0 EC50(nM) = 50.0 |
| 38 | Q07869_S44 | S44 | n/a | n/a | n/a | (2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic acid | n/a | |
| 39 | Q07869_SAU | SAU | n/a | 5154 | CHEMBL417799 | 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium | n/a | |
| 40 | Q07869_WY1 | WY1 | n/a | 5694 | CHEMBL295416 | 2-({4-CHLORO-6-[(2,3-DIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL}SULFANYL)ACETIC ACID | n/a | |
| 41 | Q07869_Y1N | Y1N | n/a | n/a | CHEMBL2204696 | 2-methyl-2-[4-[2-[4-[(E)-phenyldiazenyl]phenoxy]ethyl]phenoxy]propanoic acid | n/a | |
| 42 | Q07869_YT3 | YT3 | n/a | 168049 | n/a | YTTRIUM (III) ION | n/a | |
| 43 | Q07869_STE | STE | DB03193 | 5281;139057051; | CHEMBL46403 | STEARIC ACID | n/a | IC50(nM) = 1100.0 EC50(nM) = 40000.0 |
| 44 | Q07869_T02 | T02 | n/a | 129147662 | CHEMBL4454999 | 1-(4-chlorophenyl)-6-methyl-3-propan-2-yl-pyrazolo[3,4-b]pyridine-4-carboxylic acid | n/a | |
| 45 | Q07869_T06 | T06 | n/a | 146036004 | CHEMBL4440299 | 6-ethyl-1-(4-fluorophenyl)-3-pentan-3-yl-pyrazolo[3,4-b]pyridine-4-carboxylic acid | n/a | |
| 46 | Q07869_T4T | T4T | DB18802 | 114924 | CHEMBL187734 | 2-tetradecylsulfanylethanoic acid | n/a | |
| 47 | Q07869_LNL | LNL | DB00132 | 5280934 | CHEMBL8739 | alpha-Linolenic acid | n/a | IC50(nM) = 1200.0 Kd(nM) = 7.9 |
| 48 | Q07869_DB00197 | n/a | DB00197 | n/a | n/a | Troglitazone | n/a | |
| 49 | Q07869_2PP | 2PP | DB00313 | n/a | n/a | Valproic acid | n/a | |
| 50 | Q07869_IMN | IMN | DB00328 | 3715 | CHEMBL6 | Indomethacin | agonist | |
| 51 | Q07869_DB00412 | n/a | DB00412 | n/a | n/a | Rosiglitazone | n/a | EC50(nM) = 240.0 |
| 52 | Q07869_DB00573 | n/a | DB00573 | n/a | n/a | Fenoprofen | activator | |
| 53 | Q07869_DB00636 | n/a | DB00636 | n/a | n/a | Clofibrate | agonist | EC50(nM) = 55000.0 |
| 54 | Q07869_DB01039 | n/a | DB01039 | n/a | n/a | Fenofibrate | agonist | IC50(nM) = 1000.0 EC50(nM) = 2000.0 |
| 55 | Q07869_DB01050 | n/a | DB01050 | n/a | n/a | Ibuprofen | activator | |
| 56 | Q07869_BBI | BBI | DB01118 | 2157 | CHEMBL633 | Amiodarone | agonist | |
| 57 | Q07869_4TX | 4TX | DB01241 | 3463 | CHEMBL457 | Gemfibrozil | agonist | EC50(nM) = 11800.0 |
| 58 | Q07869_AND | AND | DB01708 | 5881 | CHEMBL90593 | Prasterone | activator | |
| 59 | Q07869_FLF | FLF | DB02266 | 3371 | CHEMBL23588 | Flufenamic acid | activator | |
| 60 | Q07869_STL | STL | DB02709 | 445154 | CHEMBL165 | Resveratrol | n/a | |
| 61 | Q07869_PHT | PHT | DB02746 | 1017;18183610; | CHEMBL1045 | Phthalic Acid | n/a | |
| 62 | Q07869_DAO | DAO | DB03017 | 3893 | CHEMBL108766 | Lauric acid | n/a | |
| 63 | Q07869_HXA | HXA | DB03756 | 445580 | CHEMBL367149 | Doconexent | activator | |
| 64 | Q07869_ELA | ELA | DB04224 | 637517 | CHEMBL460657 | Oleic Acid | n/a | |
| 65 | Q07869_OCA | OCA | DB04519 | 379;135372298; | CHEMBL324846 | Caprylic acid | n/a | |
| 66 | Q07869_DB04971 | n/a | DB04971 | n/a | n/a | Reglitazar | agonist | |
| 67 | Q07869_DB05187 | n/a | DB05187 | n/a | n/a | Elafibranor | agonist | |
| 68 | Q07869_7T1 | 7T1 | DB05416 | 9803963 | CHEMBL38943 | Cardarine | agonist | IC50(nM) = 463.0 EC50(nM) = 229.0 |
| 69 | Q07869_DB06510 | n/a | DB06510 | n/a | n/a | Muraglitazar | modulator | |
| 70 | Q07869_DB06521 | n/a | DB06521 | n/a | n/a | Ertiprotafib | n/a | |
| 71 | Q07869_DB06533 | n/a | DB06533 | n/a | n/a | Ragaglitazar | n/a | |
| 72 | Q07869_MYR | MYR | DB08231 | 11005 | CHEMBL111077 | Myristic acid | n/a | IC50(nM) = 5400.0 EC50(nM) = 13000.0 |
| 73 | Q07869_DB09006 | n/a | DB09006 | n/a | n/a | Clinofibrate | n/a | |
| 74 | Q07869_DB09064 | n/a | DB09064 | n/a | n/a | Ciprofibrate | agonist | |
| 75 | Q07869_IBP | IBP | DB09213 | 39912 | CHEMBL175 | Dexibuprofen | n/a | |
| 76 | Q07869_DB12007 | n/a | DB12007 | n/a | n/a | Isoflavone | agonist | |
| 77 | Q07869_LTB | LTB | DB12961 | 5280492 | CHEMBL65061 | Leukotriene B4 | activator |