Gene name: SOS1
Protein name: Son of sevenless
List of molecules and drugs that interact with protein Q07889
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q07889_2PX | 2PX | n/a | 73167574 | CHEMBL4166974 | N-{1-[(5-methyl-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide | n/a | |
| 2 | Q07889_2PZ | 2PZ | n/a | 117072009 | CHEMBL4169930 | N-[1-(1H-indol-3-ylmethyl)piperidin-4-yl]glycinamide | n/a | |
| 3 | Q07889_5UU | 5UU | n/a | 15995882 | n/a | 6-chloranyl-~{N}-(4-fluorophenyl)-1,2,3,4-tetrahydroacridin-9-amine | n/a | |
| 4 | Q07889_5UV | 5UV | n/a | 20858349 | n/a | 7-chloranyl-~{N}-(3-chloranyl-4-fluoranyl-phenyl)-1,2,3,4-tetrahydroacridin-9-amine | n/a | |
| 5 | Q07889_5UW | 5UW | n/a | 133107882 | CHEMBL5414348 | ~{N}-(3,3-diphenylpropyl)piperidin-4-amine | n/a | |
| 6 | Q07889_5UX | 5UX | n/a | 20859023 | CHEMBL5429481 | 6-chloranyl-~{N}-(3-chloranyl-4-fluoranyl-phenyl)-1,2,3,4-tetrahydroacridin-9-amine | n/a | |
| 7 | Q07889_6W2 | 6W2 | n/a | 755965 | CHEMBL3414689 | 4-METHOXY-N-(1,3-THIAZOL-2-YL)BENZENESULFONAMIDE | n/a | |
| 8 | Q07889_AWT | AWT | n/a | 135336459 | CHEMBL5428389 | 6,7-dimethoxy-2-methyl-~{N}-[(1~{R})-1-[3-(1~{H}-pyrazol-4-yl)phenyl]ethyl]quinazolin-4-amine | n/a | |
| 9 | Q07889_AWW | AWW | n/a | 137348959 | n/a | [2-[5-[(1~{R})-1-[(6,7-dimethoxy-2-methyl-5,8-dihydroquinazolin-4-yl)amino]ethyl]thiophen-2-yl]phenyl]methanol | n/a | |
| 10 | Q07889_AWZ | AWZ | n/a | 137322661 | n/a | ~{N}-[(1~{R})-1-[5-(6,7-dihydro-5~{H}-pyrrolo[1,2-a]imidazol-3-yl)thiophen-2-yl]ethyl]-6,7-dimethoxy-2-methyl-quinazolin-4-amine | n/a | |
| 11 | Q07889_AXE | AXE | n/a | 137322660 | CHEMBL5412768 | 6,7-dimethoxy-~{N}-[(1~{R})-1-naphthalen-1-ylethyl]quinazolin-4-amine | n/a | |
| 12 | Q07889_AXH | AXH | n/a | 137322663 | CHEMBL4535474 | 6,7-dimethoxy-2-methyl-~{N}-[(1~{R})-1-[4-[2-(methylaminomethyl)phenyl]thiophen-2-yl]ethyl]quinazolin-4-amine | n/a | |
| 13 | Q07889_BME | BME | DB03345 | 1567 | CHEMBL254951 | BETA-MERCAPTOETHANOL | n/a | |
| 14 | Q07889_BOQ | BOQ | n/a | 607286 | CHEMBL1584149 | ethyl 2-(aminomethyl)-5-~{tert}-butyl-furan-3-carboxylate | n/a | |
| 15 | Q07889_BPW | BPW | n/a | 6485772 | n/a | 3-(4-chlorophenyl)propan-1-amine | n/a | |
| 16 | Q07889_BQ2 | BQ2 | n/a | 16769566 | n/a | 1-(3,4-dihydro-1~{H}-isoquinolin-2-yl)-2-oxidanyl-ethanone | n/a | |
| 17 | Q07889_BQ5 | BQ5 | n/a | 45791645 | n/a | (1-phenyl-5,6-dihydro-4~{H}-cyclopenta[c]pyrazol-3-yl)methanamine | n/a | |
| 18 | Q07889_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 19 | Q07889_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 20 | Q07889_DXO | DXO | n/a | 90657102 | CHEMBL3414690 | 2-(2,6-DIMETHYLPHENYL)-4-(METHYLSULFANYL)-6-(PIPERAZIN-1-YL)-1,3,5-TRIAZINE | n/a | |
| 21 | Q07889_EAS | EAS | n/a | 134821715 | CHEMBL4167713 | 5-chloro-N-{1-[(5-chloro-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide | n/a | |
| 22 | Q07889_EAV | EAV | n/a | 134821716 | CHEMBL4175584 | N-{1-[(5-chloro-1H-indol-3-yl)methyl]piperidin-4-yl}-6-methyl-L-tryptophanamide | n/a | |
| 23 | Q07889_EBV | EBV | n/a | 134821718 | n/a | (2S)-2-amino-1-[(3aR,6aS)-5-[(5-chloro-1H-indol-3-yl)methyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-3-(1H-indol-3-yl)propan-1-one | n/a | |
| 24 | Q07889_EBY | EBY | n/a | 134821717 | CHEMBL4162049 | N-{1-[(5-chloro-1H-indol-3-yl)methyl]piperidin-4-yl}-5-methyl-L-tryptophanamide | n/a | |
| 25 | Q07889_EC4 | EC4 | n/a | 134821714 | CHEMBL4160484 | 6-chloro-N-{1-[(5-chloro-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide | n/a | |
| 26 | Q07889_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 27 | Q07889_FFS | FFS | n/a | 1285085 | CHEMBL1198227 | N~2~-(3-chlorophenyl)-N~4~-[(furan-2-yl)methyl]quinazoline-2,4-diamine | n/a | |
| 28 | Q07889_FFV | FFV | n/a | 137322682 | CHEMBL4245081 | N~2~-(3-chloro-4-fluorophenyl)-N~4~-[(1R)-1-cyclopropylethyl]quinazoline-2,4-diamine | n/a | |
| 29 | Q07889_FFY | FFY | n/a | 137322683 | CHEMBL4243567 | N~2~-(3-chloro-4-fluorophenyl)-N~4~-[(1R)-1-cyclopropylethyl]-8-(1,2,3,6-tetrahydropyridin-4-yl)quinazoline-2,4-diamine | n/a | |
| 30 | Q07889_FK1 | FK1 | n/a | 676493 | CHEMBL3414692 | 6-bromo-1H-indole | n/a | |
| 31 | Q07889_FMT | FMT | DB01942 | 284;18971002; | CHEMBL116736 | FORMIC ACID | n/a | |
| 32 | Q07889_FV4 | FV4 | n/a | 134814240 | CHEMBL4218552 | 6-chloro-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-2-(piperazin-1-yl)-1H-benzimidazole | n/a | |
| 33 | Q07889_FV7 | FV7 | n/a | 134814239 | CHEMBL4214176 | 6-chloro-4-(2-chlorophenyl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-2-(piperazin-1-yl)-1H-benzimidazole | n/a | |
| 34 | Q07889_FVD | FVD | n/a | 134814238 | CHEMBL4205543 | 6-chloro-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-2-(piperazin-1-yl)-4-(1,2,3,6-tetrahydropyridin-4-yl)-1H-benzimidazole | n/a | |
| 35 | Q07889_FVG | FVG | n/a | 134814237 | CHEMBL4215257 | 1-[(2S)-1-{6-chloro-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-2-(piperazin-1-yl)-1H-benzimidazol-4-yl}pyrrolidin-2-yl]methanamine | n/a | |
| 36 | Q07889_FVJ | FVJ | n/a | 134814236 | CHEMBL4217599 | 6-chloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-2-(piperazin-1-yl)-1H-benzimidazole | n/a | |
| 37 | Q07889_FVM | FVM | n/a | 134814235 | CHEMBL4214703 | 6-chloro-2-(2,6-diazaspiro[3.3]heptan-2-yl)-4-(3,5-dimethyl-1H-pyrazol-4-yl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-1H-benzimidazole | n/a | |
| 38 | Q07889_FVV | FVV | n/a | 883012 | CHEMBL1624889 | 10-[(4-fluorophenyl)methyl]-2,3,4,10-tetrahydropyrimido[1,2-a]benzimidazole | n/a | |
| 39 | Q07889_FVY | FVY | n/a | 134814243 | CHEMBL4203733 | 1-[(3-chloro-4-fluorophenyl)methyl]-5,6-dimethyl-1H-benzimidazol-2-amine | n/a | |
| 40 | Q07889_FW4 | FW4 | n/a | 134814242 | CHEMBL4210860 | 1-[(3-chloro-4-fluorophenyl)methyl]-5,6-dimethyl-2-(piperazin-1-yl)-1H-benzimidazole | n/a | |
| 41 | Q07889_FW7 | FW7 | n/a | 134814241 | CHEMBL4217465 | 6-chloro-1-[(3-chloro-4-fluorophenyl)methyl]-2-(piperazin-1-yl)-1H-benzimidazole | n/a | |
| 42 | Q07889_FWA | FWA | n/a | 134814234 | CHEMBL4213025 | 6-chloro-2-(2,6-diazaspiro[3.3]heptan-2-yl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-4-(4-methylpiperazin-1-yl)-1H-benzimidazole | n/a | |
| 43 | Q07889_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 44 | Q07889_HXY | HXY | n/a | 12738004 | CHEMBL3414691 | 1-(4-bromobenzyl)pyrrolidine | n/a | |
| 45 | Q07889_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 46 | Q07889_L71 | L71 | n/a | 137349675 | n/a | (3S)-3-[3-(aminomethyl)phenyl]-1-ethylpyrrolidine-2,5-dione | n/a | |
| 47 | Q07889_L7H | L7H | n/a | 138911318 | CHEMBL4519023 | ~{N}-[(1~{R})-1-[3-azanyl-5-(trifluoromethyl)phenyl]ethyl]-7-methoxy-2-methyl-6-[(3~{S})-oxolan-3-yl]oxy-quinazolin-4-amine | n/a | |
| 48 | Q07889_L7S | L7S | n/a | 137349677 | n/a | 3-[(3R)-1-ethyl-2,5-dioxopyrrolidin-3-yl]benzamide | n/a | |
| 49 | Q07889_LBK | LBK | n/a | 6926621 | CHEMBL1714813 | 6,7-dimethoxy-~{N}-[(1~{R})-1-phenylethyl]quinazolin-4-amine | n/a | |
| 50 | Q07889_NEN | NEN | DB01902 | 16842 | n/a | 1-ETHYL-PYRROLIDINE-2,5-DIONE | n/a | |
| 51 | Q07889_NKF | NKF | n/a | 156526655 | CHEMBL5192659 | 2-methyl-3-[(1R)-1-{[4-methyl-7-(morpholin-4-yl)pyrido[3,4-d]pyridazin-1-yl]amino}ethyl]benzonitrile | n/a | |
| 52 | Q07889_NL0 | NL0 | n/a | 156495874 | CHEMBL5208088 | 4-methyl-N-{(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl}-7-(piperazin-1-yl)phthalazin-1-amine | n/a | |
| 53 | Q07889_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 54 | Q07889_QTA | QTA | n/a | 877164 | n/a | 3-(phenylsulfonyl)benzene-1-sulfonamide | n/a | |
| 55 | Q07889_QTD | QTD | n/a | 838564 | CHEMBL4641882 | 4-phenoxybenzene-1-sulfonamide | n/a | |
| 56 | Q07889_QTG | QTG | n/a | 24319582 | CHEMBL4644614 | 4-fluoro-2-methyl-N-propylbenzene-1-sulfonamide | n/a | |
| 57 | Q07889_QTJ | QTJ | n/a | 43342694 | CHEMBL4643768 | 4-(3-chloro-4-fluorophenoxy)benzene-1-sulfonamide | n/a | |
| 58 | Q07889_QTM | QTM | n/a | 154573621 | CHEMBL4636993 | 3-(2-aminoethyl)-4-(3-chloro-4-fluorophenoxy)benzene-1-sulfonamide | n/a | |
| 59 | Q07889_QTS | QTS | n/a | 743900 | CHEMBL1314048 | 1-[(4-chlorophenyl)methyl]-1H-benzimidazol-2-amine | n/a | |
| 60 | Q07889_QTV | QTV | n/a | 2728093 | CHEMBL4635871 | 1-[(4-fluorophenyl)methyl]-2-methyl-4-nitro-1H-imidazole | n/a | |
| 61 | Q07889_RND | RND | n/a | 73167576 | CHEMBL4172691 | N-[1-(1H-indol-3-ylmethyl)piperidin-4-yl]-L-tryptophanamide | n/a | |
| 62 | Q07889_RV1 | RV1 | n/a | 90657103 | CHEMBL3414693 | N-[(4-aminophenyl)sulfonyl]cyclopropanecarboxamide | n/a | |
| 63 | Q07889_S2Q | S2Q | n/a | 25521651 | n/a | 3-propan-2-yl-~{N}-[(1~{R})-1-(3-sulfamoylphenyl)ethyl]-[1,2]oxazolo[5,4-b]pyridine-5-carboxamide | n/a | |
| 64 | Q07889_S2W | S2W | n/a | 155818534 | CHEMBL5084055 | ~{N}-[(1~{R})-1-[3-azanyl-5-(trifluoromethyl)phenyl]ethyl]-2-methyl-quinazolin-4-amine | n/a | |
| 65 | Q07889_S2Z | S2Z | n/a | 142432918 | CHEMBL5087955 | 6,7-dimethoxy-2-methyl-~{N}-[(1~{R})-1-phenylethyl]quinazolin-4-amine | n/a | |
| 66 | Q07889_S3Q | S3Q | n/a | 155818531 | CHEMBL5084571 | 6,7-dimethoxy-2-methyl-~{N}-[(1~{R})-1-[3-(trifluoromethyl)phenyl]ethyl]quinazolin-4-amine | n/a | |
| 67 | Q07889_S3T | S3T | n/a | 155818532 | CHEMBL5087341 | ~{N}-[(1~{R})-1-(3-aminophenyl)ethyl]-6,7-dimethoxy-2-methyl-quinazolin-4-amine | n/a | |
| 68 | Q07889_S3Z | S3Z | n/a | 155818533 | CHEMBL5088924 | ~{N}-[(1~{R})-1-[3-azanyl-5-(trifluoromethyl)phenyl]ethyl]-6,7-dimethoxy-2-methyl-quinazolin-4-amine | n/a | |
| 69 | Q07889_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 70 | Q07889_UMK | UMK | n/a | 93911 | CHEMBL1505419 | 4-(4-BROMOPHENYL)PIPERIDIN-4-OL | n/a | |
| 71 | Q07889_VJP | VJP | n/a | 90657104 | CHEMBL3414694 | 1-[(4-aminophenyl)sulfonyl]piperidin-2-one | n/a |