Gene name:
Protein name: Dihydroorotate dehydrogenase (quinone),
List of molecules and drugs that interact with protein Q08210
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q08210_2V6 | 2V6 | n/a | 51031042 | CHEMBL3289672 | N-[3,5-difluoro-4-(trifluoromethyl)phenyl]-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine | n/a | |
| 2 | Q08210_5Y5 | 5Y5 | n/a | 137348414 | n/a | 2-[1,1-bis(fluoranyl)ethyl]-~{N}-[(2~{S})-7-bromanyl-1,2,3,4-tetrahydronaphthalen-2-yl]-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine | n/a | |
| 3 | Q08210_78Z | 78Z | n/a | 122552662 | CHEMBL4557830 | 2-(1,1-difluoroethyl)-5-methyl-N-[6-(trifluoromethyl)pyridin-3-yl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine | n/a | |
| 4 | Q08210_8IE | 8IE | n/a | 156600311 | n/a | (4R)-3-methyl-5-[(4R)-4-methyl-3,4-dihydroisoquinolin-2(1H)-yl]thieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidine | n/a | |
| 5 | Q08210_A26 | A26 | DB08880 | 54684141 | CHEMBL973 | (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide | inhibitor | |
| 6 | Q08210_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | inhibitor | |
| 7 | Q08210_D59 | D59 | n/a | 799096 | CHEMBL217893 | N-(3,5-dichlorophenyl)-2-methyl-3-nitrobenzamide | n/a | |
| 8 | Q08210_D65 | D65 | DB12397 | 51347395 | CHEMBL1956285 | 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine | n/a | |
| 9 | Q08210_D67 | D67 | n/a | 51349276 | CHEMBL1738786 | 2-(1,1-difluoroethyl)-5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine | n/a | |
| 10 | Q08210_F1T | F1T | n/a | 134814265 | n/a | 3,6-dimethyl-~{N}-[4-(trifluoromethyl)phenyl]-[1,2]oxazolo[5,4-d]pyrimidin-4-amine | n/a | |
| 11 | Q08210_FMN | FMN | DB03247 | 643976 | CHEMBL1201794 | FLAVIN MONONUCLEOTIDE | n/a | |
| 12 | Q08210_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 13 | Q08210_J4Z | J4Z | DB08006 | 24882195 | CHEMBL475814 | N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine | n/a | IC50(nM) = 56.0 |
| 14 | Q08210_J5Z | J5Z | DB08008 | 25263414 | CHEMBL492529 | 5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine | n/a | IC50(nM) = 280.0 |
| 15 | Q08210_JZ8 | JZ8 | n/a | 49867180 | n/a | 5-methyl-7-(naphthalen-2-ylamino)-1H-[1,2,4]triazolo[1,5-a]pyrimidine-3,8-diium | n/a | |
| 16 | Q08210_LDA | LDA | DB04147 | 15433 | CHEMBL1233973 | LAURYL DIMETHYLAMINE-N-OXIDE | inhibitor | |
| 17 | Q08210_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 18 | Q08210_N8E | N8E | DB08249 | 159866 | n/a | 3,6,9,12,15-PENTAOXATRICOSAN-1-OL | inhibitor | |
| 19 | Q08210_O8A | O8A | n/a | 46846313 | CHEMBL1234899 | N-cyclopropyl-5-[2-methyl-5-(trifluoromethoxy)-1H-benzimidazol-1-yl]thiophene-2-carboxamide | n/a | |
| 20 | Q08210_ORO | ORO | DB02262 | 967;5280334; | CHEMBL1235017 | OROTIC ACID | inhibitor | |
| 21 | Q08210_P4K | P4K | n/a | 76871872 | n/a | polyethylene glycol | n/a | |
| 22 | Q08210_RL7 | RL7 | n/a | 146020610 | CHEMBL4635646 | N-cyclopropyl-4-{[2-fluoro-4-(trifluoromethyl)phenyl]methyl}-3-methyl-1H-pyrrole-2-carboxamide | n/a | |
| 23 | Q08210_RLA | RLA | n/a | 146020611 | CHEMBL4642145 | ethyl 3,5-dimethyl-4-{[4-(trifluoromethyl)phenyl]methyl}-1H-pyrrole-2-carboxylate | n/a | |
| 24 | Q08210_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 25 | Q08210_XAJ | XAJ | n/a | 155908674 | CHEMBL4877462 | ethyl 3-methyl-4-{[4-(trifluoromethyl)-1,3-benzoxazol-7-yl]methyl}-1H-pyrrole-2-carboxylate | n/a | |
| 26 | Q08210_XBY | XBY | n/a | 155908675 | n/a | 3-methyl-N-[(1R)-1-(5-methyl-1,2-oxazol-3-yl)ethyl]-4-{[4-(trifluoromethyl)phenyl]methyl}-1H-pyrrole-2-carboxamide | n/a | |
| 27 | Q08210_XC7 | XC7 | n/a | 155908677 | n/a | 3-methyl-N-[(1R)-1-(1H-1,2,4-triazol-3-yl)ethyl]-4-{1-[6-(trifluoromethyl)pyridin-3-yl]cyclopropyl}-1H-pyrrole-2-carboxamide | n/a | |
| 28 | Q08210_XCD | XCD | n/a | 155908676 | n/a | 3-methyl-N-[(1R)-1-(5-methyl-1,2-oxazol-3-yl)ethyl]-4-[6-(trifluoromethyl)-1H-indol-3-yl]-1H-pyrrole-2-carboxamide | n/a | |
| 29 | Q08210_XCM | XCM | n/a | 155908678 | n/a | 3-methyl-N-[(1R)-1-(5-methyl-1H-pyrazol-3-yl)ethyl]-4-{1-[6-(trifluoromethyl)pyridin-3-yl]cyclopropyl}-1H-pyrrole-2-carboxamide | n/a | |
| 30 | Q08210_XCV | XCV | n/a | 155908679 | n/a | N-[(1R)-1-(5-cyano-1H-pyrazol-3-yl)ethyl]-3-methyl-4-{1-[6-(trifluoromethyl)pyridin-3-yl]cyclopropyl}-1H-pyrrole-2-carboxamide | n/a | |
| 31 | Q08210_XE7 | XE7 | n/a | 155908680 | n/a | 3-{(1R)-1-[(3-methyl-4-{[6-(trifluoromethyl)pyridin-3-yl]methyl}-1H-pyrrole-2-carbonyl)amino]ethyl}-1H-pyrazole-5-carboxamide | n/a |