Gene name: PDE4D
Protein name: 3',5'-cyclic-AMP phosphodiesterase 4D
List of molecules and drugs that interact with protein Q08499
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q08499_0MO | 0MO | DB06842 | 6603746 | CHEMBL1229585 | (4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one | n/a | |
| 2 | Q08499_0X8 | 0X8 | n/a | 156619936 | CHEMBL4855047 | (~{E})-4-[8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-9-oxidanyl-6-oxidanylidene-pyrano[3,2-b]xanthen-5-yl]oxybut-2-enoic acid | n/a | |
| 3 | Q08499_15X | 15X | n/a | 44537809 | CHEMBL1229663 | 1-{4-[(2-fluoro-6-methoxy-3'-nitrobiphenyl-3-yl)methyl]phenyl}urea | n/a | |
| 4 | Q08499_1AS | 1AS | n/a | 156619937 | CHEMBL4877549 | (~{E})-4-[9-[(4-fluorophenyl)methoxy]-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-6-oxidanylidene-pyrano[3,2-b]xanthen-5-yl]oxybut-2-enoic acid | n/a | |
| 5 | Q08499_1GF | 1GF | n/a | 156619938 | CHEMBL4877677 | (~{Z})-4-[9-[(4-fluorophenyl)methoxy]-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-6-oxidanylidene-pyrano[3,2-b]xanthen-5-yl]oxybut-2-enoic acid | n/a | |
| 6 | Q08499_2SR | 2SR | n/a | 86580367 | n/a | (2R)-8-(3,4-dimethoxyphenyl)-6-methyl-2-(tetrahydro-2H-pyran-4-yl)-2H-chromen-4-ol | n/a | |
| 7 | Q08499_3DE | 3DE | DB07051 | 46937046 | n/a | 3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER | n/a | |
| 8 | Q08499_3GJ | 3GJ | n/a | 86223089 | n/a | N-(3,5-dichloropyridin-4-yl)-3-[(3-ethyl-1,2-oxazol-5-yl)methoxy]-4-methoxybenzamide | n/a | |
| 9 | Q08499_3KQ | 3KQ | n/a | 66829828 | CHEMBL3315083 | N-benzyl-2-{6-[(3,5-dichloropyridin-4-yl)acetyl]-2,3-dimethoxyphenoxy}acetamide | n/a | |
| 10 | Q08499_3NG | 3NG | DB15408 | 24748573 | CHEMBL1230165 | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | n/a | |
| 11 | Q08499_4DE | 4DE | DB04469 | 656965 | CHEMBL1230268 | 1-(4-METHOXYPHENYL)-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER | n/a | IC50(nM) = 2000.0 |
| 12 | Q08499_4I7 | 4I7 | n/a | 145706985 | n/a | (4~{a}~{S},8~{a}~{R})-4-[4-methoxy-3-[[2-(trifluoromethyl)phenyl]methoxy]phenyl]-2-(1-thieno[3,2-d]pyrimidin-4-ylpiperidin-4-yl)-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | n/a | |
| 13 | Q08499_5DE | 5DE | DB03183 | 656966 | CHEMBL1230397 | 1-(4-AMINOPHENYL)-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER | n/a | IC50(nM) = 160.0 |
| 14 | Q08499_6M5 | 6M5 | n/a | 71719394 | CHEMBL2326941 | (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-methoxy-3-[4-[4-(1~{H}-1,2,3,4-tetrazol-5-yl)phenoxy]butoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | n/a | |
| 15 | Q08499_6PT | 6PT | n/a | 10452194 | CHEMBL3978291 | 4-[(5-acetyl-2-ethyl-3-oxo-6-phenyl-2,3-dihydropyridazin-4-yl)amino]benzoic acid | n/a | |
| 16 | Q08499_6Q2 | 6Q2 | n/a | 53493858 | CHEMBL4064370 | 4-[(3-methoxyphenyl)amino]-2-phenyl-7,8-dihydro-1,6-naphthyridin-5(6H)-one | n/a | |
| 17 | Q08499_7DE | 7DE | DB01959 | 656969 | CHEMBL1230564 | 3,5-DIMETHYL-1-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER | n/a | IC50(nM) = 21.0 |
| 18 | Q08499_7DJ | 7DJ | n/a | 137045445 | n/a | N-[(2R)-2,3-dihydroxy-2-methylpropyl]-8-(methylamino)-6-[(2,3,5,6-tetrafluorophenyl)amino]imidazo[1,2-b]pyridazine-3-carboxamide | n/a | |
| 19 | Q08499_863 | 863 | n/a | 145945967 | n/a | 5-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-isopropyl-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one | n/a | |
| 20 | Q08499_8G7 | 8G7 | n/a | 162678590 | n/a | (2R,4S)-2-(2-hydroxyethyl)-2,6-dimethyl-4-(2-methylprop-1-enyl)-3,4-dihydropyrano[3,2-c][1,8]naphthyridin-5-one | n/a | |
| 21 | Q08499_8GO | 8GO | n/a | 162679616 | CHEMBL5171560 | (2R,4S)-6-ethyl-2-(2-hydroxyethyl)-2,8-dimethyl-4-(2-methylprop-1-enyl)-3,4-dihydropyrano[3,2-c][1,8]naphthyridin-5-one | n/a | |
| 22 | Q08499_988 | 988 | n/a | 9819356 | CHEMBL127944 | 8-(3-nitrophenyl)-6-(pyridin-4-ylmethyl)quinoline | n/a | |
| 23 | Q08499_A0O | A0O | n/a | 10228 | CHEMBL52229 | 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one | n/a | |
| 24 | Q08499_A1L61 | A1L61 | n/a | 5495929 | CHEMBL561643 | 8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-5,9-bis(oxidanyl)pyrano[3,2-b]xanthen-6-one | n/a | |
| 25 | Q08499_A9L | A9L | DB05676 | 11561674 | CHEMBL514800 | N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide | n/a | |
| 26 | Q08499_AH3 | AH3 | n/a | 139267726 | CHEMBL4440925 | 7-ethoxy-6-methoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde | n/a | |
| 27 | Q08499_AH6 | AH6 | n/a | 139267727 | CHEMBL4525913 | 6-ethoxy-7-methoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde | n/a | |
| 28 | Q08499_AH9 | AH9 | n/a | 11138678 | CHEMBL4455732 | 6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde | n/a | |
| 29 | Q08499_AJL | AJL | n/a | 139267728 | CHEMBL4466435 | (1S)-1-[(1H-indol-3-yl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde | n/a | |
| 30 | Q08499_AJR | AJR | n/a | 6918386 | CHEMBL80713 | 2,2'-{[6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-yl)-9H-purin-2-yl]azanediyl}di(ethan-1-ol) | n/a | |
| 31 | Q08499_AJX | AJX | n/a | 139267729 | CHEMBL4572934 | (1S)-1-[3-(1H-indol-3-yl)propyl]-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde | n/a | |
| 32 | Q08499_AK0 | AK0 | n/a | 139267730 | CHEMBL4592339 | (1S)-1-[2-(6-fluoro-1H-indol-3-yl)ethyl]-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde | n/a | |
| 33 | Q08499_AKJ | AKJ | n/a | 134693728 | n/a | 1-[4-(difluoromethoxy)-3-{[(3S)-oxolan-3-yl]oxy}phenyl]-3-methylbutan-1-one | n/a | |
| 34 | Q08499_AKO | AKO | n/a | 138393292 | CHEMBL4527894 | (1S)-6,7-dimethoxy-1-[2-(6-methyl-1H-indol-3-yl)ethyl]-3,4-dihydroisoquinoline-2(1H)-carbaldehyde | n/a | |
| 35 | Q08499_AKU | AKU | n/a | 139267731 | CHEMBL4520636 | (1S)-1-[2-(1H-indol-3-yl)ethyl]-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde | n/a | |
| 36 | Q08499_AMP | AMP | DB00131 | 6083 | CHEMBL752 | ADENOSINE MONOPHOSPHATE | product of | |
| 37 | Q08499_AQL | AQL | n/a | 166625051 | CHEMBL5437810 | 8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-9-oxidanyl-5-(pyridin-4-ylmethoxy)pyrano[3,2-b]xanthen-6-one | n/a | |
| 38 | Q08499_AWI | AWI | n/a | 165412714 | CHEMBL5407967 | 9-(cyclopropylmethoxy)-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-5-(pyridin-4-ylmethoxy)pyrano[3,2-b]xanthen-6-one | n/a | |
| 39 | Q08499_B3P | B3P | DB02676 | 125132 | CHEMBL63859 | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 40 | Q08499_B6V | B6V | n/a | 164575881 | n/a | (2~{R},4~{S})-6-ethyl-2-[(2~{E})-2-hydroxyiminoethyl]-2,8-dimethyl-4-(2-methylprop-1-enyl)-3,4-dihydropyrano[3,2-c][1,8]naphthyridin-5-one | n/a | |
| 41 | Q08499_BTB | BTB | n/a | 81462 | n/a | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 42 | Q08499_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 43 | Q08499_CIO | CIO | DB03849 | n/a | CHEMBL511115 | CILOMILAST | inhibitor | |
| 44 | Q08499_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 45 | Q08499_CMP | CMP | DB02527 | 6076 | CHEMBL316966 | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | n/a | |
| 46 | Q08499_CV8 | CV8 | n/a | 133084112 | n/a | 2-[(~{E})-(3-cyclopentyloxy-4-methoxy-phenyl)methylideneamino]oxy-1-[(2~{R},6~{S})-2,6-dimethylmorpholin-4-yl]ethanone | n/a | |
| 47 | Q08499_CZK | CZK | n/a | 133084113 | n/a | (2~{S})-1-[3-(3-cyclopentyloxy-4-methoxy-phenyl)pyrazol-1-yl]-3-morpholin-4-yl-propan-2-ol | n/a | |
| 48 | Q08499_CZQ | CZQ | n/a | 133084115 | n/a | 2-[(~{E})-[4-[bis(fluoranyl)methoxy]-3-cyclopentyloxy-phenyl]methylideneamino]oxy-1-[(2~{R},6~{R})-2,6-dimethylmorpholin-4-yl]ethanone | n/a | |
| 49 | Q08499_CZT | CZT | n/a | 133084114 | n/a | (2~{R})-1-[(~{E})-(3-cyclopentyloxy-4-methoxy-phenyl)methylideneamino]oxy-3-[(2~{R},6~{S})-2,6-dimethylmorpholin-4-yl]propan-2-ol | n/a | |
| 50 | Q08499_D08 | D08 | n/a | 137349147 | n/a | 2-[(5~{R})-3-(3-cyclopentyloxy-4-methoxy-phenyl)-4,5-dihydro-1,2-oxazol-5-yl]-~{N},~{N}-bis(2-hydroxyethyl)ethanamide | n/a | |
| 51 | Q08499_D0B | D0B | n/a | 133084116 | n/a | 3-[3-(3-cyclopentyloxy-4-methoxy-phenyl)pyrazol-1-yl]-1-[(2~{R},6~{R})-2,6-dimethylmorpholin-4-yl]propan-1-one | n/a | |
| 52 | Q08499_D0E | D0E | n/a | 118305347 | n/a | 3-[3-(3-cyclopentyloxy-4-methoxy-phenyl)pyrazol-1-yl]-1-morpholin-4-yl-propan-1-one | n/a | |
| 53 | Q08499_D5N | D5N | n/a | 133084130 | n/a | (2~{S})-1-[5-[4-[bis(fluoranyl)methoxy]-3-cyclopentyloxy-phenyl]pyrazol-1-yl]-3-morpholin-4-yl-propan-2-ol | n/a | |
| 54 | Q08499_D5T | D5T | n/a | 137700766 | CHEMBL4441748 | 1-[2-[4-[(4~{a}~{S},8~{a}~{R})-4-(3,4-dimethoxyphenyl)-1-oxidanylidene-4~{a},5,8,8~{a}-tetrahydrophthalazin-2-yl]piperi din-1-yl]-2-oxidanylidene-ethyl]-4,4-dimethyl-piperidine-2,6-dione | n/a | |
| 55 | Q08499_D5Z | D5Z | n/a | 137700768 | CHEMBL4524402 | (4aS,8aR)-2-[1-(2-aminoquinazolin-4-yl)piperidin-4-yl]-4-(3,4-dimethoxyphenyl)-1,2,4a,5,8,8a-hexahydrophthalazin-1-one | n/a | |
| 56 | Q08499_D62 | D62 | n/a | 137700767 | CHEMBL4460623 | (4aS,8aR)-2-(1-{2-aminothieno[2,3-d]pyrimidin-4-yl}piperidin-4-yl)-4-(3,4- dimethoxyphenyl)-1,2,4a,5,8,8a-hexahydrophthalazin-1-one | n/a | |
| 57 | Q08499_D68 | D68 | n/a | 137700769 | CHEMBL4530777 | 1-(2-{4-[(4aS,8aR)-4-[3,4-bis(difluoromethoxy)phenyl]-1-oxo-1,2,4a,5,8,8a-hexahydrophthalazin-2-yl]piperidin-1-yl}-2-oxoethyl)-4,4-dimethylpiperidine-2,6-dione | n/a | |
| 58 | Q08499_D71 | D71 | n/a | 9842556 | CHEMBL1232082 | 1-(3-nitrophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione | n/a | |
| 59 | Q08499_DD5 | DD5 | n/a | 133084129 | CHEMBL5286787 | (2~{R})-1-[3-[4-[bis(fluoranyl)methoxy]-3-cyclopentyloxy-phenyl]pyrazol-1-yl]-3-morpholin-4-yl-propan-2-ol | n/a | |
| 60 | Q08499_DEE | DEE | DB04271 | 215436 | CHEMBL506972 | 3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER | n/a | IC50(nM) = 82000.0 |
| 61 | Q08499_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 62 | Q08499_DTT | DTT | DB04447 | 439196 | CHEMBL406270 | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | n/a | |
| 63 | Q08499_E31 | E31 | n/a | 74221424 | CHEMBL4573171 | 2-(4-{[2-(3-chlorophenyl)-6-ethylpyrimidin-4-yl]methyl}phenyl)acetamide | n/a | |
| 64 | Q08499_E3Q | E3Q | n/a | 138753174 | n/a | 1-cycloheptyl-3-{4-methoxy-3-[(2-methoxyphenyl)methoxy]phenyl}-4,4-dimethyl-4,5-dihydro- 1H-pyrazol-5-one | n/a | |
| 65 | Q08499_E6E | E6E | n/a | 138753177 | n/a | 4-{4-methoxy-3-[(2-methoxyphenyl)methoxy]phenyl}-2-(1-{thieno[3,2-d]pyrimidin-4-yl}piperidin-4-yl)-1,2,4a,5,8,8a-hexahydrophthalazin-1-one | n/a | |
| 66 | Q08499_E6N | E6N | n/a | 138753178 | n/a | (4~{a}~{S},8~{a}~{S})-4-[4-methoxy-3-[(2-methoxyphenyl)methoxy]phenyl]-2-[1-(3-nitroimidazo[1,2-b]pyridazin-6-yl)piperidin-4-yl]-4~{a},5,6,7,8,8~{a}-hexahydrophthalazin-1-one | n/a | |
| 67 | Q08499_E6Z | E6Z | n/a | 138753179 | CHEMBL4465919 | 3-{5-[(4aR,8aS)-3-cycloheptyl-4-oxo-3,4,4a,5,8,8a-hexahydrophthalazin-1-yl]-2-methoxyphenyl}prop-2-ynamide | n/a | |
| 68 | Q08499_E8H | E8H | n/a | 9827600 | CHEMBL4566742 | 1-(2-{4-[(4aS,8aR)-4-(3,4-dimethoxyphenyl)-1-oxo-1,2,4a,5,8,8a-hexahydrophthalazin-2-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione | n/a | |
| 69 | Q08499_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 70 | Q08499_EOH | EOH | DB00898 | 702 | CHEMBL545 | ETHANOL | n/a | |
| 71 | Q08499_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 72 | Q08499_EQC | EQC | DB16880 | 64981 | CHEMBL435734 | Arctigenin | n/a | |
| 73 | Q08499_EV1 | EV1 | DB01113 | 4680 | CHEMBL19224 | 1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXYISOQUINOLINE | inhibitor | IC50(nM) = 1400.0 |
| 74 | Q08499_FFZ | FFZ | n/a | 138454907 | CHEMBL4436770 | 3-[5-[(4aR,8aS)-4-OXIDANYLIDENE-3-PROPAN-2-YL-4a,5,8,8a-TETRAHYDROPHTHALAZIN-1-YL]-2-METHOXY-PHENYL]-N-(PHENYLMETHYL)PROP-2-YNAMIDE | n/a | |
| 75 | Q08499_FTX | FTX | n/a | 155923496 | CHEMBL4848137 | (1S)-1-[(7-chloranyl-1H-indol-3-yl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carbaldehyde | n/a | |
| 76 | Q08499_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 77 | Q08499_IBM | IBM | DB07954 | 3758 | CHEMBL275084 | 3-ISOBUTYL-1-METHYLXANTHINE | inhibitor | IC50(nM) = 31000.0 |
| 78 | Q08499_IHM | IHM | n/a | 78225170 | n/a | N-(3-{1-[(1S)-1-[3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl]-2-(1-oxidopyridin-4-yl)ethyl]-1H-pyrazol-3-yl}phenyl)acetamide | n/a | |
| 79 | Q08499_ILE | ILE | DB00167 | 6306;7043901; | CHEMBL1233584 | ISOLEUCINE | n/a | |
| 80 | Q08499_J20 | J20 | n/a | 76283664 | CHEMBL4460827 | 1-[2-(4-hydroxyphenyl)ethynyl]-9,9-bis(4-methoxyphenyl)-7-oxidanyl-fluorene-2-carbaldehyde | n/a | |
| 81 | Q08499_J25 | J25 | n/a | 30515311 | CHEMBL1922946 | diethyl 2-[(thiophen-2-ylacetyl)amino]-4,7-dihydrothieno[2,3-c]pyridine-3,6(5H)-dicarboxylate | n/a | |
| 82 | Q08499_J2E | J2E | n/a | 71460717 | CHEMBL2171660 | 1-cycloheptyl-3-[3-(cyclopentyloxy)-4-methoxyphenyl]-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one | n/a | |
| 83 | Q08499_JN0 | JN0 | n/a | 5317764 | CHEMBL491515 | 3-[3-(3-methylbut-2-enyl)-4,5-bis(oxidanyl)phenyl]-5,7-bis(oxidanyl)chromen-4-one | n/a | |
| 84 | Q08499_JN4 | JN4 | n/a | 137349602 | n/a | ethenyl 6-(ethenylcarbamoyl)-2-[(phenylacetyl)amino]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate | n/a | |
| 85 | Q08499_JN7 | JN7 | n/a | 137349603 | n/a | 3-cyclopentyl 6-ethenyl 2-[(thiophen-2-ylacetyl)amino]-4,7-dihydrothieno[2,3-c]pyridine-3,6(5H)-dicarboxylate | n/a | |
| 86 | Q08499_JN8 | JN8 | n/a | 53393811 | CHEMBL1923065 | cyclopentyl 6-(ethylcarbamoyl)-2-[(thiophen-2-ylacetyl)amino]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate | n/a | |
| 87 | Q08499_JU3 | JU3 | n/a | 5281789 | CHEMBL4061300 | 3-[3-(3-methylbut-2-enyl)-2,4-bis(oxidanyl)phenyl]-5,7-bis(oxidanyl)chromen-4-one | n/a | |
| 88 | Q08499_JX2 | JX2 | n/a | 138857410 | CHEMBL4464777 | 3-[5-[(4~{a}~{R},8~{a}~{S})-3-cycloheptyl-4-oxidanylidene-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-yl]-2-methoxy-phenyl]-~{N}-(furan-2-ylmethyl)prop-2-ynamide | n/a | |
| 89 | Q08499_KR4 | KR4 | n/a | 74221301 | CHEMBL4570605 | 2-(4-{[4-(3-chlorophenyl)-6-ethyl-1,3,5-triazin-2-yl]amino}phenyl)ethan-1-ol | n/a | |
| 90 | Q08499_KR7 | KR7 | DB14790 | 90111638 | CHEMBL4541964 | (4-{[2-(3-chlorophenyl)-6-(trifluoromethyl)pyridin-4-yl]methyl}phenyl)acetic acid | inhibitor | |
| 91 | Q08499_KRD | KRD | n/a | 74221360 | CHEMBL4544243 | 2-(4-{[4-(3-chlorophenyl)-6-ethyl-1,3,5-triazin-2-yl]amino}phenyl)acetamide | n/a | |
| 92 | Q08499_M36 | M36 | n/a | 145997874 | CHEMBL4471352 | 7-[8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-5-oxidanyl-6-oxidanylidene-pyrano[3,2-b]xanthen-9-yl]oxyheptanoic acid | n/a | |
| 93 | Q08499_M98 | M98 | n/a | 6420180 | n/a | (S)-3-(2-(3-CYCLOPROPOXY-4-(DIFLUOROMETHOXY)PHENYL)-2-(5-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)THIAZOL-2-YL)ETHY L)PYRIDINE 1-OXIDE | n/a | |
| 94 | Q08499_M99 | M99 | n/a | 6420181 | n/a | (R)-3-(2-(3-CYCLOPROPOXY-4-(DIFLUOROMETHOXY)PHENYL)-2-(5-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)THIAZOL-2-YL)ETHYL)PYRIDINE 1-OXIDE | n/a | |
| 95 | Q08499_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 96 | Q08499_MPD | MPD | DB03564 | 5288834 | n/a | (4S)-2-METHYL-2,4-PENTANEDIOL | n/a | |
| 97 | Q08499_NI | NI | n/a | 934 | n/a | NICKEL (II) ION | n/a | |
| 98 | Q08499_NPV | NPV | DB08299 | 9999276 | CHEMBL74078 | 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid | n/a | IC50(nM) = 1.0 |
| 99 | Q08499_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 100 | Q08499_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 101 | Q08499_PIL | PIL | DB01791 | 154575 | CHEMBL42126 | 3-(CYCLOPENTYLOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-METHOXYBENZAMIDE | inhibitor | IC50(nM) = 0.021 |
| 102 | Q08499_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 103 | Q08499_PRO | PRO | DB00172 | 145742;6971047; | CHEMBL54922 | PROLINE | n/a | |
| 104 | Q08499_QDT | QDT | n/a | 71611998 | CHEMBL4747201 | 2-methylpropyl 1-[8-methoxy-5-(1-oxidanylidene-3~{H}-2-benzofuran-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropane-1-carboxylate | n/a | |
| 105 | Q08499_QWT | QWT | n/a | 71460703 | CHEMBL2171452 | 1-cycloheptyl-3-(4-methoxy-3-{4-[4-(1H-1,2,3,4-tetrazol-5-yl)phenoxy]butoxy}phenyl)-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one | n/a | |
| 106 | Q08499_QWZ | QWZ | n/a | 71449884 | CHEMBL2171459 | 1-cycloheptyl-3-{4-methoxy-3-[2-(4-methoxyphenyl)ethoxy]phenyl}-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one | n/a | |
| 107 | Q08499_R4H | R4H | n/a | n/a | n/a | 2-cycloheptyl-5-[4-methoxy-3-[[4-(1~{H}-1,2,3,4-tetrazol-5-yl)phenyl]methoxy]phenyl]-4,4-dimethyl-pyrazolidin-3-one | n/a | |
| 108 | Q08499_R5Z | R5Z | n/a | n/a | n/a | 1-cycloheptyl-3-[4-methoxy-3-(2-phenylethoxy)phenyl]-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one | n/a | |
| 109 | Q08499_R75 | R75 | DB12319 | 2333 | CHEMBL388590 | [3,5-bis(bromanyl)-4-oxidanyl-phenyl]-(2-ethyl-1-benzofuran-3-yl)methanone | n/a | |
| 110 | Q08499_R91 | R91 | n/a | 134693727 | n/a | 1-[4-(difluoromethoxy)-3-{[(3R)-oxolan-3-yl]oxy}phenyl]-3-methylbutan-1-one | n/a | |
| 111 | Q08499_RLW | RLW | n/a | 71457038 | CHEMBL2171659 | 3-(3-cyclopentyloxy-4-methoxy-phenyl)-4,4-dimethyl-1~{H}-pyrazol-5-one | n/a | |
| 112 | Q08499_ROF | ROF | DB01656 | 449193 | CHEMBL193240 | 3-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-(DIFLUOROMETHOXY)BENZAMIDE | inhibitor | IC50(nM) = 0.13 |
| 113 | Q08499_ROL | ROL | DB04149 | 448055 | CHEMBL430893 | ROLIPRAM | n/a | IC50(nM) = 231.0 |
| 114 | Q08499_S8Q | S8Q | n/a | 155926549 | n/a | 2-[(~{Z})-1-(3-cyclopentyloxy-4-methoxy-phenyl)ethylideneamino]oxy-1-[(2~{S},6~{S})-2,6-dimethylmorpholin-4-yl]ethanone | n/a | |
| 115 | Q08499_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 116 | Q08499_VIC | VIC | n/a | 3280 | CHEMBL1555736 | 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline | n/a | |
| 117 | Q08499_ZAR | ZAR | DB02918 | 5723 | CHEMBL313842 | 6-(4-DIFLUOROMETHOXY-3-METHOXY-PHENYL)-2H-PYRIDAZIN-3-ONE | n/a | IC50(nM) = 160.0 |
| 118 | Q08499_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 119 | Q08499_T3K | T3K | n/a | 155926552 | n/a | 3-[(~{E})-1-(3-cyclopentyloxy-4-methoxy-phenyl)ethylideneamino]oxy-1-morpholin-4-yl-propan-1-one | n/a | |
| 120 | Q08499_DB00651 | n/a | DB00651 | n/a | n/a | Dyphylline | inhibitor | |
| 121 | Q08499_DB01088 | n/a | DB01088 | n/a | n/a | Iloprost | inducer | |
| 122 | Q08499_DB01954 | n/a | DB01954 | n/a | n/a | Rolipram | inhibitor | |
| 123 | Q08499_DB03606 | n/a | DB03606 | n/a | n/a | (S)-Rolipram | n/a | |
| 124 | Q08499_DB05219 | n/a | DB05219 | n/a | n/a | Crisaborole | inhibitor | |
| 125 | Q08499_AVL | AVL | DB05266 | 3671 | CHEMBL19449 | Ibudilast | inhibitor | IC50(nM) = 166.0 |
| 126 | Q08499_DB05298 | n/a | DB05298 | n/a | n/a | Tetomilast | n/a | |
| 127 | Q08499_SLO | SLO | DB06246 | 5472495 | CHEMBL488025 | Exisulind | n/a |