Q12809 KCNH2_HUMAN
Gene name: KCNH2
Protein name: Voltage-gated inwardly rectifying

List of molecules and drugs that interact with protein Q12809

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	Q12809_FVX	FVX	DB00176	5324346	CHEMBL814	Fluvoxamine	n/a
2	Q12809_ERY	ERY	DB00199	12560	CHEMBL532	Erythromycin	inhibitor	IC50(nM) = 39.0
3	Q12809_DB00204	n/a	DB00204	n/a	n/a	Dofetilide	inhibitor	Ki(nM) = 6.4 IC50(nM) = 4.1
4	Q12809_DB00252	n/a	DB00252	n/a	n/a	Phenytoin	inhibitor	IC50(nM) = 100000.0
5	Q12809_ASW	ASW	DB00276	2179	CHEMBL43	Amsacrine	inhibitor	IC50(nM) = 208.93
6	Q12809_DB00280	n/a	DB00280	n/a	n/a	Disopyramide	inhibitor	IC50(nM) = 12000.0
7	Q12809_DB00308	n/a	DB00308	n/a	n/a	Ibutilide	inhibitor	IC50(nM) = 10.0
8	Q12809_DB00342	n/a	DB00342	n/a	n/a	Terfenadine	inhibitor	Ki(nM) = 56.0 IC50(nM) = 8.9
9	Q12809_DB00455	n/a	DB00455	n/a	n/a	Loratadine	antagonist	IC50(nM) = 169.82
10	Q12809_XRA	XRA	DB00457	4893	CHEMBL2	Prazosin	inhibitor	IC50(nM) = 1584.89
11	Q12809_IXX	IXX	DB00458	3696	CHEMBL11	Imipramine	inhibitor	IC50(nM) = 3388.0
12	Q12809_DB00472	n/a	DB00472	n/a	n/a	Fluoxetine	inhibitor	IC50(nM) = 457.09
13	Q12809_Z80	Z80	DB00477	2726	CHEMBL71	Chlorpromazine	inhibitor	IC50(nM) = 1470.0
14	Q12809_DB00489	n/a	DB00489	n/a	n/a	Sotalol	inhibitor
15	Q12809_CPF	CPF	DB00537	2764;4011971;	CHEMBL8	Ciprofloxacin	n/a	Ki(nM) = 100000.0 IC50(nM) = 30000.0
16	Q12809_DB00557	n/a	DB00557	n/a	n/a	Hydroxyzine	inhibitor
17	Q12809_DB00604	n/a	DB00604	n/a	n/a	Cisapride	inhibitor
18	Q12809_XB7	XB7	DB00637	2247	CHEMBL296419	Astemizole	inhibitor	Ki(nM) = 2.9 IC50(nM) = 0.9 EC50(nM) = 1.9
19	Q12809_DB00661	n/a	DB00661	n/a	n/a	Verapamil	inhibitor	IC50(nM) = 141.0
20	Q12809_CTX	CTX	DB00675	2733526	CHEMBL83	Tamoxifen	inhibitor	IC50(nM) = 1584.89
21	Q12809_DB00679	n/a	DB00679	n/a	n/a	Thioridazine	inhibitor	Ki(nM) = 191.0 IC50(nM) = 33.0
22	Q12809_DB00836	n/a	DB00836	n/a	n/a	Loperamide	blocker	IC50(nM) = 33.0
23	Q12809_QDN	QDN	DB00908	441074	CHEMBL1294	Quinidine	inhibitor	IC50(nM) = 324.0
24	Q12809_DB01026	n/a	DB01026	n/a	n/a	Ketoconazole	inhibitor
25	Q12809_DB01035	n/a	DB01035	n/a	n/a	Procainamide	inhibitor	IC50(nM) = 138038.43
26	Q12809_DB01074	n/a	DB01074	n/a	n/a	Perhexiline	n/a	IC50(nM) = 7762.0
27	Q12809_1II	1II	DB01100	16362	CHEMBL1423	Pimozide	inhibitor	Ki(nM) = 18.0 IC50(nM) = 3.02
28	Q12809_DB01136	n/a	DB01136	n/a	n/a	Carvedilol	inhibitor	IC50(nM) = 350.0
29	Q12809_DB01142	no_lig_id	DB01142	n/a	n/a	Doxepin	inhibitor
30	Q12809_DB01149	n/a	DB01149	n/a	n/a	Nefazodone	antagonist
31	Q12809_DB01162	n/a	DB01162	n/a	n/a	Terazosin	inhibitor	IC50(nM) = 17782.79
32	Q12809_DB01182	n/a	DB01182	n/a	n/a	Propafenone	inhibitor	IC50(nM) = 440.0
33	Q12809_DB01195	n/a	DB01195	n/a	n/a	Flecainide	inhibitor	IC50(nM) = 3890.0
34	Q12809_CTY	CTY	DB01211	84029	CHEMBL1741	Clarithromycin	n/a	IC50(nM) = 33113.0
35	Q12809_DB01218	n/a	DB01218	n/a	n/a	Halofantrine	inhibitor	Ki(nM) = 7500.0 IC50(nM) = 40.0
36	Q12809_DB01244	n/a	DB01244	n/a	n/a	Bepridil	inhibitor	Ki(nM) = 184.0 IC50(nM) = 22.91
37	Q12809_DB04855	n/a	DB04855	n/a	n/a	Dronedarone	inhibitor	IC50(nM) = 316.23
38	Q12809_DB04957	n/a	DB04957	n/a	n/a	Azimilide	n/a
39	Q12809_DB06144	n/a	DB06144	n/a	n/a	Sertindole	inhibitor	Ki(nM) = 3.0 IC50(nM) = 2.7
40	Q12809_DB06217	n/a	DB06217	n/a	n/a	Vernakalant	blocker
41	Q12809_DB06457	n/a	DB06457	n/a	n/a	Tecastemizole	n/a
42	Q12809_DB11090	n/a	DB11090	n/a	n/a	Potassium nitrate	agonist
43	Q12809_DB11186	n/a	DB11186	n/a	n/a	Pentoxyverine	inhibitor
44	Q12809_DB11386	n/a	DB11386	n/a	n/a	Chlorobutanol	n/a
45	Q12809_QKM	QKM	DB11633	6918485	CHEMBL409153	Isavuconazole	inhibitor
46	Q12809_DB11642	n/a	DB11642	n/a	n/a	Pitolisant	blocker