Gene name: GRIN2A
Protein name: Glutamate receptor ionotropic,
List of molecules and drugs that interact with protein Q12879
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q12879_5YC | 5YC | n/a | 20938953 | CHEMBL3797274 | 7-[[ethyl(phenyl)amino]methyl]-2-methyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one | n/a | |
| 2 | Q12879_5YD | 5YD | n/a | 5165428 | n/a | 4-[[(4-fluorophenyl)sulfonylamino]methyl]-~{N}-(pyridin-3-ylmethyl)benzamide | n/a | |
| 3 | Q12879_5YE | 5YE | n/a | 118017713 | CHEMBL4583809 | 6-[[ethyl-(4-fluorophenyl)amino]methyl]-2,3-dihydro-1~{H}-cyclopenta[3,4][1,3]thiazolo[1,4-~{a}]pyrimidin-8-one | n/a | |
| 4 | Q12879_67H | 67H | n/a | 118017587 | CHEMBL3800614 | 7-{[ethyl(4-fluorophenyl)amino]methyl}-N,2-dimethyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide | n/a | |
| 5 | Q12879_67J | 67J | n/a | 118009479 | CHEMBL3797818 | N-ethyl-7-{[2-fluoro-3-(trifluoromethyl)phenyl]methyl}-2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide | n/a | |
| 6 | Q12879_6RM | 6RM | n/a | 118009262 | CHEMBL3800265 | 7-[(4-fluoranylphenoxy)methyl]-3-[(1~{R},2~{R})-2-(hydroxymethyl)cyclopropyl]-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one | n/a | |
| 7 | Q12879_6RV | 6RV | n/a | 127046129 | CHEMBL3799213 | (1~{R},2~{R})-2-[7-[[5-chloranyl-3-(trifluoromethyl)pyrazol-1-yl]methyl]-5-oxidanylidene-2-(trifluoromethyl)-[1,3]thiazolo[3,2-a]pyrimidin-3-yl]cyclopropane-1-carbonitrile | n/a | |
| 8 | Q12879_7H0 | 7H0 | n/a | 118017739 | CHEMBL3799694 | 7-{[5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-N-ethyl-2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide | n/a | |
| 9 | Q12879_7H2 | 7H2 | n/a | 134157459 | CHEMBL3983039 | (1R,2R)-2-(2-{[5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-6-yl)cyclopropane-1-carbonitrile | n/a | |
| 10 | Q12879_7RC | 7RC | n/a | 6603754 | CHEMBL47277 | (2R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid | n/a | |
| 11 | Q12879_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 12 | Q12879_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 13 | Q12879_GLU | GLU | DB00142 | 33032;44272391;88747398; | CHEMBL575060 | GLUTAMIC ACID | n/a | IC50(nM) = 70.0 |
| 14 | Q12879_GLY | GLY | DB00145 | 750;5257127; | CHEMBL773 | GLYCINE | antagonist | |
| 15 | Q12879_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 16 | Q12879_JC9 | JC9 | DB11823 | 182137 | CHEMBL395091 | (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one | antagonist | |
| 17 | Q12879_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 18 | Q12879_GGL | GGL | DB00142 | 33032;44272391;88747398; | CHEMBL575060 | Glutamic acid | n/a | IC50(nM) = 70.0 |
| 19 | Q12879_DB00145 | n/a | DB00145 | n/a | n/a | Glycine | antagonist | |
| 20 | Q12879_DB00454 | n/a | DB00454 | n/a | n/a | Meperidine | antagonist | |
| 21 | Q12879_DB00949 | n/a | DB00949 | n/a | n/a | Felbamate | antagonist | |
| 22 | Q12879_DB01159 | n/a | DB01159 | n/a | n/a | Halothane | antagonist | |
| 23 | Q12879_DB01520 | n/a | DB01520 | n/a | n/a | Tenocyclidine | antagonist | |
| 24 | Q12879_SC2 | SC2 | DB06151 | 12035 | CHEMBL600 | Acetylcysteine | activator |