Gene name: DPYD
Protein name: Dihydropyrimidine dehydrogenase [NADP(+)]
List of molecules and drugs that interact with protein Q12882
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q12882_IDH | IDH | DB02303 | 5288605 | n/a | (5S)-5-Iododihydro-2,4(1H,3H)-pyrimidinedione | inhibitor | |
| 2 | Q12882_NDP | NDP | DB02338 | 5884;134821689; | CHEMBL407009 | NADPH | n/a | |
| 3 | Q12882_UAA | UAA | DB03048 | 73271;5289524; | CHEMBL593503 | 6-Carboxymethyluracil | inhibitor | |
| 4 | Q12882_FAD | FAD | DB03147 | 643975 | CHEMBL1232653 | Flavin adenine dinucleotide | inhibitor | |
| 5 | Q12882_FMN | FMN | DB03247 | 643976 | CHEMBL1201794 | Flavin mononucleotide | n/a | |
| 6 | Q12882_URA | URA | DB03419 | 1174;5274267; | CHEMBL566 | Uracil | modulator | |
| 7 | Q12882_Y3G | Y3G | DB03516 | 43157;5273947; | CHEMBL355200 | Eniluracil | modulator | IC50(nM) = 14.0 |
| 8 | Q12882_IUR | IUR | DB03554 | 69672;5285918; | CHEMBL1173 | 5-Iodouracil | inhibitor | IC50(nM) = 220.0 |
| 9 | Q12882_DB09257 | n/a | DB09257 | n/a | n/a | Gimeracil | inhibitor | |
| 10 | Q12882_DB09327 | n/a | DB09327 | n/a | n/a | Tegafur-uracil | antagonist |