Gene name: PAK1
Protein name: Serine/threonine-protein kinase PAK
List of molecules and drugs that interact with protein Q13153
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q13153_0H2 | 0H2 | n/a | n/a | n/a | [1,3-dioxo-6-(pyridin-2-yl-kappaN)-2,3-dihydro-1H-isoindol-5-yl-kappaC~5~][(thioxomethylidene)azanido-kappaN](1,4,7-trithionane-kappa~3~S~1~,S~4~,S~7~)ruthenium | n/a | |
| 2 | Q13153_107 | 107 | DB06844 | 1712 | n/a | 4-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDE | n/a | |
| 3 | Q13153_1ST | 1ST | n/a | 11963532 | n/a | (5S,6R,7R,9R)-12-HYDROXY-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[ B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE | n/a | |
| 4 | Q13153_2K0 | 2K0 | n/a | 77232204 | CHEMBL3596912 | [2-chloro-5-(hydroxymethyl)phenyl]{5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridin-3-yl}methanone | n/a | |
| 5 | Q13153_2OL | 2OL | n/a | 68181954 | CHEMBL3128042 | 1-({1-(2-aminopyrimidin-4-yl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl}ethynyl)cyclohexanol | n/a | |
| 6 | Q13153_4OQ | 4OQ | n/a | 91808045 | CHEMBL3609330 | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | n/a | |
| 7 | Q13153_4OR | 4OR | n/a | 91808046;135567021; | CHEMBL3609371 | (S)-N-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | n/a | |
| 8 | Q13153_4PV | 4PV | n/a | 137125256 | CHEMBL3609328 | 2,8-difluoro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine | n/a | |
| 9 | Q13153_4T3 | 4T3 | n/a | 91809512 | CHEMBL3580949 | 2-(4-aminopiperidin-1-yl)-N-(5-cyclopropyl-1H-pyrazol-3-yl)thieno[3,2-d]pyrimidin-4-amine | n/a | |
| 10 | Q13153_4T5 | 4T5 | n/a | n/a | CHEMBL3580962 | N~2~-[(trans-4-aminocyclohexyl)methyl]-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine | n/a | |
| 11 | Q13153_4T6 | 4T6 | n/a | 89766097 | CHEMBL3580974 | N~2~-[(7-chloro-1H-benzimidazol-6-yl)methyl]-N~4~-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine | n/a | |
| 12 | Q13153_59N | 59N | n/a | n/a | CHEMBL3770909 | 8-[(trans-4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8H)-one | n/a | |
| 13 | Q13153_59T | 59T | n/a | n/a | CHEMBL3770443 | 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one | n/a | |
| 14 | Q13153_59U | 59U | n/a | 71557891 | CHEMBL3770186 | 6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-{[2-(1-methylpiperidin-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one | n/a | |
| 15 | Q13153_6BZ | 6BZ | n/a | 119057464 | CHEMBL3818592 | 8-(3-aminopropyl)-6-[2-chloro-4-(3-methyl-2-oxopyrazin-1(2H)-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one | n/a | |
| 16 | Q13153_7KC | 7KC | DB11775 | 25227462 | CHEMBL3128043 | PF-3758309 | n/a | |
| 17 | Q13153_ANP | ANP | n/a | 33113 | CHEMBL1230989 | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | n/a | |
| 18 | Q13153_ATP | ATP | DB00171 | 5957 | CHEMBL14249 | ADENOSINE-5'-TRIPHOSPHATE | n/a | |
| 19 | Q13153_C7Y | C7Y | n/a | 71611421 | CHEMBL3824314 | N~4~-(5-cyclopropyl-1H-pyrazol-3-yl)-N~2~-[(1S)-1-(1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine | n/a | |
| 20 | Q13153_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 21 | Q13153_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 22 | Q13153_DW1 | DW1 | n/a | n/a | n/a | Ruthenium pyridocarbazole | n/a | |
| 23 | Q13153_FLL | FLL | n/a | 49866989 | n/a | OCTAHEDRAL RU-PYRIDOCARBAZOLE | n/a | |
| 24 | Q13153_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 25 | Q13153_IOD | IOD | n/a | 30165 | n/a | IODIDE ION | n/a | |
| 26 | Q13153_IPV | IPV | n/a | 25014511 | CHEMBL1762546 | [4-methyl-3-[methyl-[2-[(3-methylsulfonyl-5-morpholin-4-yl-phenyl)amino]pyrimidin-4-yl]amino]phenyl]methanol | n/a | |
| 27 | Q13153_IPW | IPW | n/a | 122164606 | CHEMBL3596908 | (4-chlorophenyl)-[5-(1-piperidin-4-ylpyrazol-4-yl)-1~{H}-pyrrolo[2,3-b]pyridin-3-yl]methanone | n/a | |
| 28 | Q13153_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 29 | Q13153_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 30 | Q13153_XR1 | XR1 | n/a | 70934541 | CHEMBL3609327 | 6-[2-chloro-4-(1,3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one | n/a | |
| 31 | Q13153_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |