Gene name: FKBP5
Protein name: Peptidyl-prolyl cis-trans isomerase
List of molecules and drugs that interact with protein Q13451
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q13451_0MC | 0MC | n/a | 56962328 | CHEMBL2059033 | {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-{[(1S,2R)-2-ethyl-1-hydroxycyclohexyl](oxo)acetyl}piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid | n/a | |
| 2 | Q13451_0MD | 0MD | n/a | 56962330 | CHEMBL2059034 | {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-{[(1R,2S)-2-ethyl-1-hydroxycyclohexyl](oxo)acetyl}piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid | n/a | |
| 3 | Q13451_0OS | 0OS | n/a | 137347879 | n/a | {3-[(1S)-1-[({(2S)-1-[(3,5-dichlorophenyl)sulfonyl]piperidin-2-yl}carbonyl)oxy]-3-(3,4-dimethoxyphenyl)propyl]phenoxy}acetic acid | n/a | |
| 4 | Q13451_1KT | 1KT | n/a | 71664584 | n/a | 1-[(9S,13R,13aR)-1,3-dimethoxy-8-oxo-5,8,9,10,11,12,13,13a-octahydro-6H-9,13-epiminoazocino[2,1-a]isoquinolin-14-yl]-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dione | n/a | |
| 5 | Q13451_1KU | 1KU | n/a | 71662959 | n/a | (1S,6R)-10-(1,3-benzothiazol-6-ylsulfonyl)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 6 | Q13451_1KY | 1KY | n/a | 71662771 | n/a | 6-({(1S,5R)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-2-oxo-3,9-diazabicyclo[3.3.1]non-9-yl}sulfonyl)-1,3-benzothiazol-2(3H)-one | n/a | |
| 7 | Q13451_1KZ | 1KZ | n/a | 71664585 | n/a | 2-(3,4-dimethoxyphenoxy)ethyl (2S)-1-[(2-oxo-2,3-dihydro-1,3-benzothiazol-6-yl)sulfonyl]piperidine-2-carboxylate | n/a | |
| 8 | Q13451_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
| 9 | Q13451_37K | 37K | n/a | 117072253 | n/a | (1R)-3-(3,4-dimethoxyphenyl)-1-{3-[2-(morpholin-4-yl)ethoxy]phenyl}propyl (2S)-1-[(2S)-2-[(1S)-cyclohex-2-en-1-yl]-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate | n/a | |
| 10 | Q13451_37L | 37L | n/a | 10723446 | n/a | (3-{(1R)-3-(3,4-dimethoxyphenyl)-1-[({(2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)pent-4-enoyl]piperidin-2-yl}carbonyl)oxy]propyl}phenoxy)acetic acid | n/a | |
| 11 | Q13451_384 | 384 | n/a | 78673864 | n/a | (1S,5S,6R)-10-[(3,5-dichlorophenyl)sulfonyl]-5-(2-methoxyethoxy)-3-(2-methoxyethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 12 | Q13451_3JP | 3JP | n/a | 86280458 | n/a | (1S,5S,6R)-10-[(3,5-dichlorophenyl)sulfonyl]-3-[2-(3,4-dimethoxyphenoxy)ethyl]-5-ethyl-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 13 | Q13451_3JQ | 3JQ | n/a | 86280456 | n/a | (1S,5S,6R)-10-[(3,5-dichlorophenyl)sulfonyl]-5-[(1R)-1,2-dihydroxyethyl]-3-[2-(3,4-dimethoxyphenoxy)ethyl]-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 14 | Q13451_3JR | 3JR | n/a | 86280457 | n/a | (1S,5S,6R)-10-[(3,5-dichlorophenyl)sulfonyl]-5-[(1S)-1,2-dihydroxyethyl]-3-[2-(3,4-dimethoxyphenoxy)ethyl]-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 15 | Q13451_4MZ | 4MZ | DB03385 | 13195 | CHEMBL1230309 | 4-METHYLIMIDAZOLE | n/a | |
| 16 | Q13451_5B8 | 5B8 | n/a | 91936975 | CHEMBL3623623 | (1R)-3-(3,4-dimethoxyphenyl)-1-{3-[2-(morpholin-4-yl)ethoxy]phenyl}propyl (2S)-1-[(2S,3R)-2-cyclohexyl-3-hydroxybutanoyl]piperidine-2-carboxylate | n/a | |
| 17 | Q13451_5BG | 5BG | n/a | 117967835 | CHEMBL3792975 | {3-[(1R)-1-[({(2S)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidin-2-yl}carbonyl)amino]-3-(3,4-dimethoxyphenyl)propyl]phenoxy}acetic acid | n/a | |
| 18 | Q13451_5BH | 5BH | n/a | 117967787 | CHEMBL3793603 | (2S)-N-(1-carbamoylcyclopentyl)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxamide | n/a | |
| 19 | Q13451_9QN | 9QN | n/a | 118257702 | n/a | (1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-(hydroxymethyl)-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 20 | Q13451_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 21 | Q13451_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 22 | Q13451_CO3 | CO3 | DB14531 | 19660 | n/a | CARBONATE ION | n/a | |
| 23 | Q13451_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 24 | Q13451_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 25 | Q13451_FK5 | FK5 | DB00864 | 445643 | CHEMBL269732 | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | n/a | Ki(nM) = 79.0 Kd(nM) = 104.0 |
| 26 | Q13451_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 27 | Q13451_GY1 | GY1 | n/a | 86277875 | CHEMBL3623612 | 2-[3-[(1~{R})-1-[(2~{S})-1-[(2~{S})-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)ethanoyl]piperidin-2-yl]carbonyloxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]ethanoic acid | n/a | |
| 28 | Q13451_HRZ | HRZ | n/a | 8871;5280522; | CHEMBL662 | 1~{H}-pyridin-2-one | n/a | |
| 29 | Q13451_HYN | HYN | n/a | 10006 | CHEMBL122334 | imidazolidine-2,4-dione | n/a | |
| 30 | Q13451_I63 | I63 | n/a | 10371065 | CHEMBL321022 | {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid | n/a | |
| 31 | Q13451_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 32 | Q13451_IS8 | IS8 | n/a | 62481 | CHEMBL1161685 | isothiocyanate | n/a | |
| 33 | Q13451_JFK | JFK | n/a | 71662960 | n/a | (1S,6R)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-10-[(2-oxo-2,3-dihydro-1,3-benzothiazol-6-yl)sulfonyl]-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 34 | Q13451_L2Q | L2Q | n/a | 145707024 | CHEMBL4588417 | [(1~{R})-3-(3,4-dimethoxyphenyl)-1-[3-(2-morpholin-4-ylethoxy)phenyl]propyl] (2~{S})-1-[[(1~{R},4~{a}~{R},8~{a}~{R})-4-oxidanylidene-2,3,4~{a},5,6,7,8,8~{a}-octahydro-1~{H}-naphthalen-1-yl]carbonyl]piperidine-2-carboxylate | n/a | |
| 35 | Q13451_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 36 | Q13451_NCA | NCA | DB02701 | 936 | CHEMBL1140 | NICOTINAMIDE | n/a | |
| 37 | Q13451_NPO | NPO | DB04417 | 980 | CHEMBL14130 | P-NITROPHENOL | n/a | |
| 38 | Q13451_R3B | R3B | n/a | 155817650 | CHEMBL4848201 | (2S,9S,12R)-2-cyclohexyl-12-[2-(3,4-dimethoxyphenyl)ethyl]-24,27-dimethoxy-11,18,22-trioxa-4-azatetracyclo[21.2.2.113,17.04,9]octacosa-1(25),13(28),14,16,23,26-hexaene-3,10-dione | n/a | |
| 39 | Q13451_R3E | R3E | n/a | 155817649 | CHEMBL4860544 | (2S,9S,12R,20Z)-2-cyclohexyl-12-[2-(3,4-dimethoxyphenyl)ethyl]-28,31-dimethoxy-11,18,23,26-tetraoxa-4-azatetracyclo[25.2.2.113,17.04,9]dotriaconta-1(29),13(32),14,16,20,27,30-heptaene-3,10-dione | n/a | |
| 40 | Q13451_RAP | RAP | DB00877 | 5284616 | CHEMBL413 | RAPAMYCIN IMMUNOSUPPRESSANT DRUG | n/a | |
| 41 | Q13451_RQW | RQW | n/a | 156905790 | n/a | (1~{S},5~{S},6~{R})-10-(1,3-benzothiazol-6-ylsulfonyl)-5-(methoxymethyl)-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 42 | Q13451_RR5 | RR5 | n/a | 156631263 | n/a | (2~{S})-2-[(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-ethyl-2-oxidanylidene-3,10-diazabicyclo[4.3.1]decan-3-yl]propanoic acid | n/a | |
| 43 | Q13451_RRZ | RRZ | n/a | 137639141 | CHEMBL4072643 | 2-[(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-ethenyl-2-oxidanylidene-3,10-diazabicyclo[4.3.1]decan-3-yl]ethanoic acid | n/a | |
| 44 | Q13451_RSB | RSB | n/a | 156905791 | n/a | (1S,5S,6R)-10-(benzo[d]thiazol-6-ylsulfonyl)-5-(methoxymethyl)-3-(pyridin-2-ylethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 45 | Q13451_RTQ | RTQ | n/a | 155899141 | n/a | (2R,5S,12R)-12-cyclohexyl-2-[2-(3,4-dimethoxyphenyl)ethyl]-3,19-dioxa-10,13,16-triazatricyclo[18.3.1.0-5,10]tetracosa- 1(24),20,22-triene-4,11,14,17-tetrone | n/a | |
| 46 | Q13451_RTT | RTT | n/a | 155899142 | CHEMBL5399355 | (2'R,5'S,12'R)-12'-cyclohexyl-2'-[2-(3,4-dimethoxyphenyl)ethyl]-3',19'-dioxa-10',13',16'-triazaspiro[cyclopropane-1,15'- tricyclo[18.3.1.0-5,10]tetracosane]-1'(24'),20',22'-triene-4',11',14',17'-tetrone | n/a | |
| 47 | Q13451_S5W | S5W | n/a | 155817656 | CHEMBL4856457 | Macrocyclic SAFit analogue 55 | n/a | |
| 48 | Q13451_S8N | S8N | n/a | 155899143 | n/a | (2~{R},5~{S},12~{R})-12-cyclohexyl-2-[2-(3,4-dimethoxyphenyl)ethyl]-15,15,16-trimethyl-3,19-dioxa-10,13,16-triazatricyclo[18.3.1.0^{5,10}]tetracosa-1(24),20,22-triene-4,11,14,17-tetrone | n/a | |
| 49 | Q13451_SCN | SCN | n/a | 9322 | n/a | THIOCYANATE ION | n/a | |
| 50 | Q13451_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 51 | Q13451_U83 | U83 | n/a | 168007527 | n/a | 2-[3-[(1~{R})-1-[(2~{S})-1-[(2~{S})-2-(5-chloranylthiophen-2-yl)-2-cyclohexyl-ethanoyl]piperidin-2-yl]carbonyloxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]ethanoic acid | n/a | |
| 52 | Q13451_U8C | U8C | n/a | 168007532 | n/a | 2-[3-[(1~{R})-1-[(2~{S})-1-[(2~{S})-2-cyclohexyl-2-thiophen-2-yl-ethanoyl]piperidin-2-yl]carbonyloxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]ethanoic acid | n/a | |
| 53 | Q13451_UBK | UBK | n/a | 168007531 | n/a | (2~{R},5~{S},12~{S})-2-[2-(3,4-dimethoxyphenyl)ethyl]-15,15-dimethyl-12-thiophen-2-yl-3,19-dioxa-10,13,16-triazatricyclo[18.3.1.0^{5,10}]tetracosa-1(24),20,22-triene-4,11,14,17-tetrone | n/a | |
| 54 | Q13451_UC0 | UC0 | n/a | 168007921 | CHEMBL5416467 | 2-[3-[(1~{R})-1-[(2~{S})-1-[(2~{S})-2-(5-chloranylthiophen-2-yl)pent-4-enoyl]piperidin-2-yl]carbonyloxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]ethanoic acid | n/a | |
| 55 | Q13451_UCF | UCF | n/a | 168007530 | CHEMBL5412795 | 2-[3-[(1~{R})-1-[(2~{S})-1-[(2~{S})-2-(5-chloranylthiophen-2-yl)butanoyl]piperidin-2-yl]carbonyloxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]ethanoic acid | n/a | |
| 56 | Q13451_UCO | UCO | n/a | 168007529 | CHEMBL5414438 | 2-[3-[(1~{R})-1-[(2~{S})-1-[(2~{S})-2-(5-chloranylthiophen-2-yl)-2-(3,4,5-trimethoxyphenyl)ethanoyl]piperidin-2-yl]carbonyloxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]ethanoic acid | n/a | |
| 57 | Q13451_UCT | UCT | n/a | 168007528 | CHEMBL5407686 | 2-[3-[(1~{R})-1-[(2~{S})-1-[(2~{S})-2-(5-chloranylthiophen-2-yl)propanoyl]piperidin-2-yl]carbonyloxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]ethanoic acid | n/a | |
| 58 | Q13451_UMR | UMR | n/a | 168477221 | n/a | (1S,5S,6R)-10-[S-[3,5-bis(chloranyl)phenyl]-N-methyl-sulfonimidoyl]-5-ethenyl-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 59 | Q13451_UT6 | UT6 | n/a | 168477222 | n/a | (1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfinyl-5-ethenyl-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 60 | Q13451_UUI | UUI | n/a | 168477833 | n/a | (1S,5S,6R)-10-[[3,5-bis(chloranyl)phenyl]sulfonimidoyl]-5-ethenyl-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | n/a | |
| 61 | Q13451_V1L | V1L | n/a | 12665 | CHEMBL12193 | piperidin-2-one | n/a | |
| 62 | Q13451_XZW | XZW | n/a | 169409277 | n/a | [(1~{R})-3-(3,4-dimethoxyphenyl)-1-[4-[[1-[3-[2-[[[(2~{S},4~{R})-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidin-2-yl]carbonylamino]methyl]-5-(4-methyl-1,3-thiazol-5-yl)phenoxy]propyl]-1,2,3-triazol-4-yl]methoxy]phenyl]propyl] (2~{S})-1-[(2~{S})-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)ethanoyl]piperidine-2-carboxylate | n/a | |
| 63 | Q13451_T58 | T58 | n/a | 155817658 | CHEMBL4868302 | 2-cyclohexyl-12-[2-(3,4-dimethoxyphenyl)ethyl]-25,26-dimethoxy-11,18,23-trioxa-4-azatetracyclo[22.3.1.113,17.04,9]nonacosa-1(27),13(29),14,16,20,24(28),25-heptaene-3,10-dione | n/a | |
| 64 | Q13451_T5B | T5B | n/a | 155817657 | CHEMBL4871144 | 2-cyclohexyl-12-[2-(3,4-dimethoxyphenyl)ethyl]-20,21-dihydroxy-25,26-dimethoxy-11,18,23-trioxa-4-azatetracyclo[22.3.1.113,17.04,9]nonacosa-1(27),13(29),14,16,24(28),25-hexaene-3,10-dione | n/a | |
| 65 | Q13451_T5H | T5H | n/a | 155817659 | n/a | 2-cyclohexyl-12-[2-(3,4-dimethoxyphenyl)ethyl]-20,21-dihydroxy-25,28-dimethoxy-11,18,23-trioxa-4-azatetracyclo[22.2.2.113,17.04,9]nonacosa-1(26),13(29),14,16,24,27-hexaene-3,10-dione | n/a |