Gene name: RIPK1
Protein name: Receptor-interacting serine/threonine-protein kinase
List of molecules and drugs that interact with protein Q13546
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q13546_1HW | 1HW | n/a | 78225511 | n/a | 1-{(3S,3aS)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl}-2-hydroxyethanone | n/a | |
| 2 | Q13546_1HX | 1HX | n/a | 24857830 | CHEMBL259796 | N-[(1S)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1H-pyrrole-2-carboxamide | n/a | |
| 3 | Q13546_3CI | 3CI | n/a | 168007913 | n/a | 1-methyl-5-[2-(2-methylpropanoylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-phenylethyl]indole-3-carboxamide | n/a | |
| 4 | Q13546_3IF | 3IF | n/a | 162396645 | CHEMBL5173634 | N-[(3S)-7-(2-cyclopropylethynyl)-5-methyl-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4H-1,2,4-triazole-3-carboxamide | n/a | |
| 5 | Q13546_3IU | 3IU | n/a | 162396646 | n/a | N-[(3S)-5-methyl-7-[2-(oxan-4-yl)ethynyl]-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4H-1,2,4-triazole-3-carboxamide | n/a | |
| 6 | Q13546_65U | 65U | n/a | 90351311 | CHEMBL3785703 | 5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide | n/a | |
| 7 | Q13546_7MJ | 7MJ | DB16875 | 77108121 | CHEMBL4071864 | 3-benzyl-N-[(3S)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-5-carboxamide | inhibitor | |
| 8 | Q13546_EJP | EJP | n/a | 132471860 | CHEMBL4100398 | (3S)-3-(2-benzyl-3-chloro-7-oxo-2,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine-8-carbonitrile | n/a | |
| 9 | Q13546_EJY | EJY | n/a | 23578 | CHEMBL4077039 | 2-benzyl-5-nitro-1H-benzimidazole | n/a | |
| 10 | Q13546_G4W | G4W | n/a | 135121928 | n/a | 6-[4-[(5~{S})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]carbonylpiperidin-1-yl]pyrimidine-4-carbonitrile | n/a | |
| 11 | Q13546_GO4 | GO4 | n/a | 168007916 | n/a | 5-[2-(cyclopropylcarbonylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-(3-fluorophenyl)ethyl]-1-methyl-indole-3-carboxamide | n/a | |
| 12 | Q13546_IOD | IOD | n/a | 30165 | n/a | IODIDE ION | n/a | |
| 13 | Q13546_JSW | JSW | n/a | 138105971 | n/a | [(5~{S})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]-[1-(5-methyl-1,3,4-oxadiazol-2-yl)piperidin-4-yl]methanone | n/a | |
| 14 | Q13546_K8K | K8K | n/a | 118557502 | CHEMBL4452233 | ~{N}-[(3~{S})-7,9-bis(fluoranyl)-2-oxidanylidene-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-3-(phenylmethyl)-1~{H}-1,2,4-triazole-5-carboxamide | n/a | |
| 15 | Q13546_L4Y | L4Y | n/a | 124178682 | CHEMBL4788837 | (5R)-5-methyl-N-[(3S)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2H-indazole-3-carboxamide | n/a | |
| 16 | Q13546_L8D | L8D | n/a | 138377384 | CHEMBL5208359 | (5S)-N-[(3S)-7-methoxy-1-methyl-2-oxo-2,3,4,5-tetrahydro-1H-pyrido[3,4-b]azepin-3-yl]-5-phenyl-6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazole-2-carboxamide | n/a | |
| 17 | Q13546_M5J | M5J | n/a | 92485003 | n/a | 1-[(2S)-2-(3-fluorophenyl)pyrrolidin-1-yl]-2,2-dimethylpropan-1-one | n/a | |
| 18 | Q13546_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 19 | Q13546_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 20 | Q13546_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 21 | Q13546_Q1A | Q1A | n/a | 71816195 | CHEMBL3109202 | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | n/a | |
| 22 | Q13546_RCM | RCM | n/a | 11288934 | CHEMBL370438 | (5R)-5-[(7-chloro-1H-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione | n/a | |
| 23 | Q13546_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 24 | Q13546_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |