Gene name: PTK6
Protein name: Protein-tyrosine kinase 6
List of molecules and drugs that interact with protein Q13882
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q13882_1N1 | 1N1 | DB01254 | 3062316 | CHEMBL1421 | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE | n/a | IC50(nM) = 5.3 Kd(nM) = 7.8 |
| 2 | Q13882_58V | 58V | n/a | 56672549 | CHEMBL1836848 | (2-chloro-4-{[6-cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone | n/a | |
| 3 | Q13882_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 4 | Q13882_FKY | FKY | n/a | 118167692 | CHEMBL4210892 | 2-{[(3R,4S)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-5-(1-methyl-1H-imidazol-4-yl)pyridine-3-carboxamide | n/a | |
| 5 | Q13882_FLJ | FLJ | n/a | 56669088 | CHEMBL1836855 | (3-fluoro-4-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone | n/a | |
| 6 | Q13882_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 7 | Q13882_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 8 | Q13882_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 9 | Q13882_ZD6 | ZD6 | DB05294 | 3081361 | CHEMBL24828 | Vandetanib | inhibitor | |
| 10 | Q13882_AV9 | AV9 | DB11800 | 9911830 | CHEMBL1289494 | Tivozanib | n/a | |
| 11 | Q13882_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
| 12 | Q13882_DB15035 | n/a | DB15035 | n/a | n/a | Zanubrutinib | inhibitor |