Gene name: CACNA1C
Protein name: Voltage-dependent L-type calcium
List of molecules and drugs that interact with protein Q13936
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q13936_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 2 | Q13936_CLR | CLR | DB04540 | 5997 | CHEMBL112570 | CHOLESTEROL | n/a | |
| 3 | Q13936_LEU | LEU | DB00149 | 6106;7045798; | CHEMBL291962 | LEUCINE | n/a | |
| 4 | Q13936_WNZ | WNZ | n/a | 9546801;90657571; | n/a | (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl dodecanoate | n/a | |
| 5 | Q13936_WO9 | WO9 | n/a | 52924242 | n/a | (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl heptadecanoate | n/a | |
| 6 | Q13936_YSW | YSW | n/a | 97044991 | n/a | (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl dodecanoate | n/a | |
| 7 | Q13936_DB00270 | n/a | DB00270 | n/a | n/a | Isradipine | inhibitor | IC50(nM) = 2.2 |
| 8 | Q13936_DB00308 | n/a | DB00308 | n/a | n/a | Ibutilide | activator | IC50(nM) = 62500.0 |
| 9 | Q13936_C9F | C9F | DB00343 | 39186 | CHEMBL23 | Diltiazem | blocker | IC50(nM) = 450.0 |
| 10 | Q13936_DB00381 | n/a | DB00381 | n/a | n/a | Amlodipine | inhibitor | IC50(nM) = 1200.0 |
| 11 | Q13936_DB00393 | n/a | DB00393 | n/a | n/a | Nimodipine | inhibitor | IC50(nM) = 110.0 |
| 12 | Q13936_DB00401 | n/a | DB00401 | n/a | n/a | Nisoldipine | inhibitor | IC50(nM) = 3.0 |
| 13 | Q13936_N90 | N90 | DB00568 | 1547484 | CHEMBL43064 | Cinnarizine | inhibitor | |
| 14 | Q13936_DB00622 | n/a | DB00622 | n/a | n/a | Nicardipine | inhibitor | IC50(nM) = 250.0 |
| 15 | Q13936_DB00661 | n/a | DB00661 | n/a | n/a | Verapamil | inhibitor | IC50(nM) = 150.0 |
| 16 | Q13936_EOH | EOH | DB00898 | 702 | CHEMBL545 | Ethanol | inhibitor | |
| 17 | Q13936_DB01023 | n/a | DB01023 | n/a | n/a | Felodipine | inhibitor | |
| 18 | Q13936_DB01054 | n/a | DB01054 | n/a | n/a | Nitrendipine | inhibitor | |
| 19 | Q13936_C5U | C5U | DB01115 | 4485 | CHEMBL193 | Nifedipine | inhibitor | IC50(nM) = 10.0 |
| 20 | Q13936_DB01373 | n/a | DB01373 | n/a | n/a | Calcium | ligand | |
| 21 | Q13936_MWV | MWV | DB01388 | 60663 | CHEMBL45816 | Mibefradil | inhibitor | IC50(nM) = 156.0 |
| 22 | Q13936_DB04855 | n/a | DB04855 | n/a | n/a | Dronedarone | inhibitor | |
| 23 | Q13936_DB04920 | n/a | DB04920 | n/a | n/a | Clevidipine | blocker | |
| 24 | Q13936_DB06712 | n/a | DB06712 | n/a | n/a | Nilvadipine | blocker | |
| 25 | Q13936_DB09227 | n/a | DB09227 | n/a | n/a | Barnidipine | antagonist | IC50(nM) = 1200.0 |
| 26 | Q13936_DB09229 | n/a | DB09229 | n/a | n/a | Aranidipine | antagonist | |
| 27 | Q13936_DB09235 | n/a | DB09235 | n/a | n/a | Efonidipine | inhibitor | |
| 28 | Q13936_6UB | 6UB | DB09237 | 9822750 | CHEMBL2111097 | Levamlodipine | antagonist | |
| 29 | Q13936_QKM | QKM | DB11633 | 6918485 | CHEMBL409153 | Isavuconazole | inhibitor | |
| 30 | Q13936_DB12278 | n/a | DB12278 | n/a | n/a | Propiverine | antagonist |