Gene name: PDE3A
Protein name: cGMP-inhibited 3',5'-cyclic phosphodiesterase
List of molecules and drugs that interact with protein Q14432
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q14432_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 2 | Q14432_AMP | AMP | DB00131 | 6083 | CHEMBL752 | ADENOSINE MONOPHOSPHATE | n/a | |
| 3 | Q14432_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 4 | Q14432_J33 | J33 | DB00261 | 2182;135409400; | CHEMBL760 | 6,7-bis(chloranyl)-3,5-dihydro-1H-imidazo[2,1-b]quinazolin-2-one | inhibitor | IC50(nM) = 50.0 |
| 5 | Q14432_J36 | J36 | n/a | 320217 | n/a | Parvine | n/a | |
| 6 | Q14432_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 7 | Q14432_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 8 | Q14432_X5M | X5M | n/a | n/a | n/a | (4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one | n/a | |
| 9 | Q14432_XKG | XKG | n/a | n/a | CHEMBL285913 | (2E)-9,10-dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-2,3,6,7-tetrahydro-4H-pyrimido[6,1-a]isoquinolin-4-one | n/a | |
| 10 | Q14432_MIL | MIL | DB00235 | 4197;5281020; | CHEMBL189 | Milrinone | inhibitor | Ki(nM) = 150.0 IC50(nM) = 210.0 |
| 11 | Q14432_TEP | TEP | DB00277 | 2153 | CHEMBL190 | Theophylline | inhibitor | IC50(nM) = 360000.0 |
| 12 | Q14432_DB00922 | n/a | DB00922 | n/a | n/a | Levosimendan | inhibitor | |
| 13 | Q14432_DB01166 | n/a | DB01166 | n/a | n/a | Cilostazol | inhibitor | |
| 14 | Q14432_DB01223 | n/a | DB01223 | n/a | n/a | Aminophylline | inhibitor | |
| 15 | Q14432_DB01303 | n/a | DB01303 | n/a | n/a | Oxtriphylline | inhibitor | |
| 16 | Q14432_DB01427 | n/a | DB01427 | n/a | n/a | Amrinone | inhibitor | IC50(nM) = 16000.0 |
| 17 | Q14432_DB04880 | n/a | DB04880 | n/a | n/a | Enoximone | inhibitor | IC50(nM) = 3800.0 |
| 18 | Q14432_AVL | AVL | DB05266 | 3671 | CHEMBL19449 | Ibudilast | inhibitor | IC50(nM) = 299000.0 |
| 19 | Q14432_JPU | JPU | DB08811 | 5502 | CHEMBL404216 | Tofisopam | inhibitor |