Gene name: PDK2
Protein name: [Pyruvate dehydrogenase (acetyl-transferring)]
List of molecules and drugs that interact with protein Q15119
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q15119_42A | 42A | n/a | 10313195 | CHEMBL4075970 | 1H-pyrrolo[2,3-b]pyridine-3-carbonitrile | n/a | |
| 2 | Q15119_5ZP | 5ZP | n/a | 162624763 | CHEMBL5090085 | (3~{S})-3-[5-(8-cyclopropyl-2-methyl-9~{H}-pyrido[2,3-b]indol-3-yl)-1,3,4-oxadiazol-2-yl]-4-methyl-~{N}-[(1~{R})-1-phenylethyl]pentanamide | n/a | |
| 3 | Q15119_67V | 67V | n/a | 162624762 | CHEMBL5073515 | methyl 8-cyclopropyl-2-methyl-9H-pyrido[2,3-b]indole-3-carboxylate | n/a | |
| 4 | Q15119_6I4 | 6I4 | n/a | 162624761 | CHEMBL5093860 | 8-cyclopropyl-2-methyl-9H-pyrido[2,3-b]indole | n/a | |
| 5 | Q15119_7F9 | 7F9 | n/a | 124201642 | CHEMBL4072775 | ~{N}-[2-(ethylamino)-2-oxidanylidene-ethyl]-~{N}-(4-methoxyphenyl)-2,4-bis(oxidanyl)benzamide | n/a | |
| 6 | Q15119_7FE | 7FE | n/a | 117972658 | CHEMBL3727843 | ~{N}-[4-(2-chloranyl-5-methyl-pyrimidin-4-yl)phenyl]-2,4-bis(oxidanyl)-~{N}-[[4-(pyrrolidin-1-ylmethyl)phenyl]methyl]benzamide | n/a | |
| 7 | Q15119_7FV | 7FV | n/a | 124201644 | CHEMBL3716663 | [2,4-bis(oxidanyl)phenyl]-[(2~{S})-2-methyl-6-(3-methylquinolin-2-yl)-3,4-dihydro-2~{H}-quinolin-1-yl]methanone | n/a | |
| 8 | Q15119_7FW | 7FW | n/a | 117972517 | CHEMBL3731789 | ~{N}-[4-[methyl(quinoxalin-6-ylmethyl)carbamoyl]phenyl]-2,4-bis(oxidanyl)-~{N}-(phenylmethyl)benzamide | n/a | |
| 9 | Q15119_7TJ | 7TJ | n/a | 86280455 | CHEMBL3727964 | N-[4-(2-CHLORO-5-METHYLPYRIMIDIN-4-YL)PHENYL]-2,4-DIHYDROXY-N-(4-{[(TRIFLUOROACETYL)AMINO]METHYL}BENZYL)BENZAMIDE | n/a | |
| 10 | Q15119_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 11 | Q15119_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 12 | Q15119_ATP | ATP | DB00171 | 5957 | CHEMBL14249 | ADENOSINE-5'-TRIPHOSPHATE | n/a | |
| 13 | Q15119_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 14 | Q15119_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 15 | Q15119_EGX | EGX | n/a | 146026196 | CHEMBL4594851 | 1-(1-piperidin-4-ylpyrazol-4-yl)anthracene-9,10-dione | n/a | |
| 16 | Q15119_EH0 | EH0 | n/a | 154700492 | n/a | 4-[[[4-[3,5-bis(fluoranyl)-4-(4-oxidanyl-4-oxidanylidene-butoxy)phenyl]-5-[5-chloranyl-2,4-bis(oxidanyl)phenyl]-1,2-oxazol-3-yl]carbonylamino]methyl]benzoic acid | n/a | |
| 17 | Q15119_EH3 | EH3 | n/a | n/a | n/a | 4-[[[5-[5-chloranyl-2,4-bis(oxidanyl)phenyl]-4-[4-(1-methylsulfonylpiperidin-4-yl)oxyphenyl]-1,2-oxazol-3-yl]carbonylamino]methyl]cyclohexane-1-carboxylic acid | n/a | |
| 18 | Q15119_FLC | FLC | n/a | 31348 | n/a | CITRATE ANION | n/a | |
| 19 | Q15119_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 20 | Q15119_J0F | J0F | n/a | 156024951 | CHEMBL4870403 | 5-bromanyl-2-methyl-6-propyl-7H-pyrrolo[2,3-d]pyrimidine | n/a | |
| 21 | Q15119_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 22 | Q15119_NL8 | NL8 | n/a | 155488702 | n/a | ~{N}-(4-aminocarbonylphenyl)-~{N}-methyl-2,4-bis(oxidanyl)benzamide | n/a | |
| 23 | Q15119_NLZ | NLZ | n/a | 76601 | n/a | 2,4-bis(oxidanyl)benzamide | n/a | |
| 24 | Q15119_NMW | NMW | n/a | 155488701 | n/a | [2,4-bis(oxidanyl)phenyl]-[(1~{S})-6,7-dimethoxy-1-pyridin-3-yl-3,4-dihydro-1~{H}-isoquinolin-2-yl]methanone | n/a | |
| 25 | Q15119_NN8 | NN8 | n/a | 155488700 | n/a | [2,4-bis(oxidanyl)phenyl]-[(1~{R})-6,7-dimethoxy-1-pyridin-3-yl-3,4-dihydro-1~{H}-isoquinolin-2-yl]methanone | n/a | |
| 26 | Q15119_P35 | P35 | n/a | 118155906 | CHEMBL4091824 | 4-({5-[(piperidin-4-yl)amino]-1,3-dihydro-2H-isoindol-2-yl}sulfonyl)benzene-1,3-diol | n/a | |
| 27 | Q15119_P46 | P46 | n/a | 124037106 | n/a | (3S)-3-amino-4-[4-({2-[(2,4-dihydroxyphenyl)sulfonyl]-2H-isoindol-5-yl}amino)piperidin-1-yl]-4-oxobutanamide | n/a | |
| 28 | Q15119_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 29 | Q15119_PFT | PFT | n/a | 11955507 | CHEMBL514290 | 4-(1,3-dihydro-2H-isoindol-2-ylcarbonyl)benzene-1,3-diol | n/a | |
| 30 | Q15119_PV0 | PV0 | n/a | 72376512 | CHEMBL4082531 | 2-[(2,4-dihydroxyphenyl)sulfonyl]-2,3-dihydro-1H-isoindole-4,6-diol | n/a | |
| 31 | Q15119_PV1 | PV1 | n/a | 15942234 | CHEMBL4168598 | (5-bromo-2,4-dihydroxyphenyl)(1,3-dihydro-2H-isoindol-2-yl)methanone | n/a | |
| 32 | Q15119_PV2 | PV2 | n/a | 57440476 | n/a | 4-(isoindolin-2-ylsulfonyl)benzene-1,3-diol | n/a | |
| 33 | Q15119_PV8 | PV8 | n/a | 72376511 | CHEMBL4062355 | 4-[(5-hydroxy-1,3-dihydro-2H-isoindol-2-yl)sulfonyl]benzene-1,3-diol | n/a | |
| 34 | Q15119_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 35 | Q15119_TF1 | TF1 | DB08608 | 6102761 | CHEMBL316388 | 4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE | n/a | |
| 36 | Q15119_TF2 | TF2 | DB08609 | 6102762 | n/a | (N-{4-[(ETHYLANILINO)SULFONYL]-2-METHYLPHENYL}-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE | n/a | |
| 37 | Q15119_TF3 | TF3 | DB08610 | 6102763 | CHEMBL1236255 | N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE | n/a | |
| 38 | Q15119_TF4 | TF4 | DB08809 | 6597 | CHEMBL13960 | DICHLORO-ACETIC ACID | n/a | IC50(nM) = 183000.0 |
| 39 | Q15119_TLA | TLA | DB09459 | 444305 | CHEMBL1236315 | L(+)-TARTARIC ACID | n/a | |
| 40 | Q15119_W6P | W6P | n/a | 321710 | CHEMBL40823 | 1,3-dihydro-2H-indol-2-one | n/a | |
| 41 | Q15119_SZ6 | SZ6 | n/a | 86280454 | CHEMBL3727577 | N-[4-(2-chloro-5-methylpyrimidin-4-yl)phenyl]-N-(4-{[(difluoroacetyl)amino]methyl}benzyl)-2,4-dihydroxybenzamide | n/a |