Gene name: DDR2
Protein name: Discoidin domain-containing receptor
List of molecules and drugs that interact with protein Q16832
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q16832_4VD | 4VD | n/a | 86764579 | CHEMBL3608786 | N-[5-({[(3-fluorophenyl)carbamoyl]amino}methyl)-2-methylphenyl]imidazo[1,2-a]pyridine-3-carboxamide | n/a | |
| 2 | Q16832_D6Q | D6Q | n/a | 130301866 | n/a | 2-[4,5-bis(fluoranyl)-2-oxidanylidene-1'-(1~{H}-pyrazolo[3,4-b]pyridin-5-ylcarbonyl)spiro[indole-3,4'-piperidine]-1-yl]-~{N}-[2,2,2-tris(fluoranyl)ethyl]ethanamide | n/a | |
| 3 | Q16832_STI | STI | DB00619 | 5291 | CHEMBL941 | Imatinib | antagonist | IC50(nM) = 141.0 Kd(nM) = 15.0 |
| 4 | Q16832_DB08896 | n/a | DB08896 | n/a | n/a | Regorafenib | inhibitor | |
| 5 | Q16832_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |