Gene name: CYP51A1
Protein name: Lanosterol 14-alpha demethylase
List of molecules and drugs that interact with protein Q16850
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q16850_DXC | DXC | DB03619 | 222528 | CHEMBL406393 | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID | n/a | |
| 2 | Q16850_ECL | ECL | n/a | 6604378 | CHEMBL1232474 | 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole | n/a | |
| 3 | Q16850_ECN | ECN | DB07705 | 12773795 | n/a | 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE | n/a | |
| 4 | Q16850_HEM | HEM | DB18267 | n/a | n/a | PROTOPORPHYRIN IX CONTAINING FE | n/a | |
| 5 | Q16850_KKK | KKK | n/a | 456201 | CHEMBL75 | 1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine | n/a | |
| 6 | Q16850_LAN | LAN | DB03696 | 246983 | CHEMBL225111 | LANOSTEROL | n/a | |
| 7 | Q16850_PJM | PJM | n/a | 139592939 | CHEMBL4522116 | N-[(1R)-1-(3-chloro-4'-fluoro[1,1'-biphenyl]-4-yl)-2-(1H-imidazol-1-yl)ethyl]-4-{5-[3-fluoro-5-(5-fluoropyrimidin-4-yl)phenyl]-1,3,4-oxadiazol-2-yl}benzamide | n/a | |
| 8 | Q16850_VFV | VFV | n/a | 119081677 | CHEMBL3629567 | N-[(1R)-1-(3,4'-difluorobiphenyl-4-yl)-2-(1H-imidazol-1-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide | n/a | |
| 9 | Q16850_DB01007 | n/a | DB01007 | n/a | n/a | Tioconazole | inhibitor | |
| 10 | Q16850_DB01167 | n/a | DB01167 | n/a | n/a | Itraconazole | n/a | IC50(nM) = 3600.0 |
| 11 | Q16850_KLN | KLN | DB05667 | 47576 | CHEMBL295698 | Levoketoconazole | inhibitor |