Gene name: PFKFB3
Protein name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase
List of molecules and drugs that interact with protein Q16875
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q16875_87T | 87T | n/a | 91668555 | n/a | N-(4-{[3-(1-methyl-1H-pyrazol-4-yl)-1H-indol-5-yl]oxy}phenyl)glycinamide | n/a | |
| 2 | Q16875_8R2 | 8R2 | n/a | 58619539 | CHEMBL3422654 | (2S)-2-amino-N-[4-[(2-amino-3-cyano-1H-indol-5-yl)oxy]phenyl]-3-hydroxy-propanamide | n/a | |
| 3 | Q16875_8V1 | 8V1 | n/a | 91668557 | CHEMBL3421731 | (2S)-N-[4-[1-METHYL-3-(1-METHYLPYRAZOL-4-YL)INDOL-5-YL]OXYPHENYL]PYRROLIDINE-2-CARBOXAMIDE | n/a | |
| 4 | Q16875_ACP | ACP | DB03909 | 91532 | CHEMBL133463 | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | n/a | |
| 5 | Q16875_ACY | ACY | DB03166 | 176;21980959;160748163; | CHEMBL539 | ACETIC ACID | n/a | |
| 6 | Q16875_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 7 | Q16875_ALF | ALF | DB04444 | 5311325;91866986;118797887;165339283; | n/a | TETRAFLUOROALUMINATE ION | n/a | |
| 8 | Q16875_BKE | BKE | n/a | 752157;135489967; | CHEMBL1469891 | 7-(4-methoxyphenyl)-5-phenyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one | n/a | |
| 9 | Q16875_BKI | BKI | n/a | 112499879;135566685; | n/a | 5-(4-bromophenyl)-7-phenyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one | n/a | |
| 10 | Q16875_BKS | BKS | n/a | 112499880;135566686; | n/a | 5-(4-chlorophenyl)-7-phenyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one | n/a | |
| 11 | Q16875_BKV | BKV | n/a | 2049550;135493519; | CHEMBL1423878 | 7-(4-bromophenyl)-5-phenyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one | n/a | |
| 12 | Q16875_BME | BME | DB03345 | 1567 | CHEMBL254951 | BETA-MERCAPTOETHANOL | n/a | |
| 13 | Q16875_BWW | BWW | n/a | 89648677 | CHEMBL5285350 | 4-[[3-(5-fluoranyl-2-oxidanyl-phenyl)phenyl]sulfonylamino]-2-oxidanyl-benzoic acid | n/a | |
| 14 | Q16875_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 15 | Q16875_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 16 | Q16875_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 17 | Q16875_EDT | EDT | DB00974 | 6049;5232305; | CHEMBL858 | {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID | n/a | |
| 18 | Q16875_F6P | F6P | n/a | 440641 | CHEMBL604196 | 6-O-phosphono-beta-D-fructofuranose | n/a | |
| 19 | Q16875_FD9 | FD9 | n/a | 91668554 | CHEMBL3422676 | (2S)-N-[4-[3-cyano-1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]indol-5-yl]oxyphenyl]pyrrolidine-2-carboxamide | n/a | |
| 20 | Q16875_FDP | FDP | n/a | 105021 | n/a | 2,6-di-O-phosphono-beta-D-fructofuranose | n/a | |
| 21 | Q16875_FLC | FLC | n/a | 31348 | n/a | CITRATE ANION | n/a | |
| 22 | Q16875_GSH | GSH | DB00143 | 124886;25246407;171390563; | CHEMBL1543 | GLUTATHIONE | n/a | |
| 23 | Q16875_GV2 | GV2 | n/a | 122690997 | CHEMBL5286061 | 3-[[8-(1-methylindol-6-yl)quinoxalin-6-yl]amino]-~{N}-(oxan-4-yl)pyridine-4-carboxamide | n/a | |
| 24 | Q16875_GV5 | GV5 | n/a | 122690982 | n/a | 8-[3-(dimethylamino)phenyl]-~{N}-(4-methylsulfonylpyridin-3-yl)quinoxalin-6-amine | n/a | |
| 25 | Q16875_GV8 | GV8 | n/a | 122690650 | n/a | 8-(3-methyl-1-benzofuran-5-yl)-~{N}-(4-methylsulfonylpyridin-3-yl)quinoxalin-6-amine | n/a | |
| 26 | Q16875_H9Z | H9Z | n/a | 137319649 | n/a | 3-[[8-(1-methylindol-6-yl)quinoxalin-6-yl]amino]-~{N}-[(3~{S})-1-methylpiperidin-3-yl]pyridine-4-carboxamide | n/a | |
| 27 | Q16875_HAK | HAK | n/a | 122689236 | CHEMBL4470835 | 3-[[8-(1-methylindol-6-yl)quinoxalin-6-yl]amino]-~{N}-pyrimidin-5-yl-pyridine-4-carboxamide | n/a | |
| 28 | Q16875_HAT | HAT | n/a | 137319650 | n/a | 3-[[8-(1-methylindol-6-yl)quinoxalin-6-yl]amino]-~{N}-[(3~{S})-1-methylpyrrolidin-3-yl]pyridine-4-carboxamide | n/a | |
| 29 | Q16875_HAW | HAW | n/a | 122690681 | CHEMBL4553861 | 2-[[8-(1-methylindol-6-yl)quinoxalin-6-yl]amino]-~{N}-(pyrimidin-5-ylmethyl)benzenesulfonamide | n/a | |
| 30 | Q16875_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 31 | Q16875_MJP | MJP | n/a | 91668556 | CHEMBL3422660 | 2-azanyl-N-[4-[(3-cyano-1H-indol-5-yl)oxy]phenyl]ethanamide | n/a | |
| 32 | Q16875_MLA | MLA | DB02175 | 867;23511544; | CHEMBL7942 | MALONIC ACID | n/a | |
| 33 | Q16875_PEP | PEP | DB01819 | 1005;58114173;59658623; | CHEMBL1235228 | PHOSPHOENOLPYRUVATE | n/a | |
| 34 | Q16875_PHS | PHS | n/a | 407 | CHEMBL1235291 | PHOSPHONIC ACID | n/a | |
| 35 | Q16875_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 36 | Q16875_POP | POP | n/a | 4995;18628280;57345951; | n/a | PYROPHOSPHATE 2- | n/a | |
| 37 | Q16875_S6L | S6L | n/a | 91668553 | CHEMBL3422658 | 2-amino-N-[4-(2-amino-1-benzyl-3-cyano-indol-5-yl)oxyphenyl]acetamide | n/a | |
| 38 | Q16875_SRT | SRT | DB14756 | 447315 | CHEMBL225983 | S,R MESO-TARTARIC ACID | n/a |