Gene name:
Protein name: Bifunctional dihydrofolate reductase-thymidylate
List of molecules and drugs that interact with protein Q27793
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q27793_1CY | 1CY | DB14763 | 9049 | CHEMBL747 | 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine | n/a | |
| 2 | Q27793_2CY | 2CY | n/a | 46829299 | n/a | 5-[3-(3-fluorophenoxy)propoxy]quinazoline-2,4-diamine | n/a | |
| 3 | Q27793_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 4 | Q27793_C50 | C50 | n/a | 46829298 | CHEMBL1231612 | 1-[3-(2,3-dichlorophenoxy)propoxy]-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine | n/a | |
| 5 | Q27793_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 6 | Q27793_DU | DU | DB03800 | 65063 | CHEMBL211312 | 2'-DEOXYURIDINE-5'-MONOPHOSPHATE | n/a | |
| 7 | Q27793_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 8 | Q27793_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 9 | Q27793_MTX | MTX | DB00563 | 126941 | CHEMBL34259 | METHOTREXATE | n/a | IC50(nM) = 1.1 |
| 10 | Q27793_NAP | NAP | DB03461 | 5885;57525501; | CHEMBL295069 | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | n/a | |
| 11 | Q27793_NDP | NDP | DB02338 | 5884;134821689; | CHEMBL407009 | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | n/a | |
| 12 | Q27793_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 13 | Q27793_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 14 | Q27793_TMQ | TMQ | DB01157 | 5582;59961053; | n/a | TRIMETREXATE | n/a | Ki(nM) = 6.6 IC50(nM) = 20.2 |
| 15 | Q27793_UMP | UMP | DB03800 | 65063 | CHEMBL211312 | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | n/a |