Gene name: pyr4
Protein name: Dihydroorotate dehydrogenase (fumarate)
List of molecules and drugs that interact with protein Q4D3W2
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q4D3W2_2RO | 2RO | n/a | 71819699 | CHEMBL3990817 | 5-[2-(4-tert-butylphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 2 | Q4D3W2_3RO | 3RO | n/a | 71819700 | CHEMBL3990764 | 5-[2-(3-chlorophenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 3 | Q4D3W2_5LL | 5LL | n/a | 690389 | n/a | 5-[(E)-3-(furan-2-yl)prop-2-enylidene]-1,3-diazinane-2,4,6-trione | n/a | |
| 4 | Q4D3W2_5LM | 5LM | n/a | 869810 | n/a | 5-[(E)-3-thiophen-2-ylprop-2-enylidene]-1,3-diazinane-2,4,6-trione | n/a | |
| 5 | Q4D3W2_CAC | CAC | n/a | 167250 | n/a | CACODYLATE ION | n/a | |
| 6 | Q4D3W2_DOR | DOR | DB02129 | 439216 | n/a | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID | n/a | |
| 7 | Q4D3W2_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 8 | Q4D3W2_ERO | ERO | n/a | 137349283 | n/a | 5-ethenyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 9 | Q4D3W2_FMN | FMN | DB03247 | 643976 | CHEMBL1201794 | FLAVIN MONONUCLEOTIDE | n/a | |
| 10 | Q4D3W2_FOT | FOT | n/a | 69711 | CHEMBL1232805 | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID | n/a | |
| 11 | Q4D3W2_FUM | FUM | DB01677 | 444972;21883788; | CHEMBL503160 | FUMARIC ACID | n/a | |
| 12 | Q4D3W2_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 13 | Q4D3W2_HRO | HRO | n/a | 233338 | n/a | 5-chloro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 14 | Q4D3W2_IRO | IRO | n/a | 381087 | n/a | 5-iodo-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 15 | Q4D3W2_JDB | JDB | n/a | 72943170 | CHEMBL3991216 | 5-[2-(7-methoxynaphthalen-2-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 16 | Q4D3W2_JDM | JDM | n/a | 72943169 | CHEMBL3990421 | 5-{2-[2-(hydroxymethyl)phenyl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 17 | Q4D3W2_KRO | KRO | n/a | 72187566 | CHEMBL3990191 | 5-[2-(4-fluoro-3-methylphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 18 | Q4D3W2_LRO | LRO | n/a | 71819697 | CHEMBL3991051 | 5-[2-(4-methylphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 19 | Q4D3W2_MRO | MRO | n/a | 71816172 | CHEMBL3990479 | 2,6-dioxo-5-(2-phenylethyl)-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 20 | Q4D3W2_NCO | NCO | DB03350 | 453369;6102370; | n/a | COBALT HEXAMMINE(III) | n/a | |
| 21 | Q4D3W2_ORO | ORO | DB02262 | 967;5280334; | CHEMBL1235017 | OROTIC ACID | n/a | |
| 22 | Q4D3W2_OXC | OXC | DB03209 | 100562 | n/a | OXONIC ACID | n/a | |
| 23 | Q4D3W2_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 24 | Q4D3W2_QRO | QRO | n/a | 72187565 | CHEMBL3991402 | 5-[2-(3,4-difluorophenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 25 | Q4D3W2_ROD | ROD | n/a | 72187569 | CHEMBL3990765 | 2,6-dioxo-5-{2-[2-(trifluoromethyl)phenyl]ethyl}-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 26 | Q4D3W2_ROE | ROE | n/a | 72376498 | CHEMBL3990079 | 5-[2-(6-methoxynaphthalen-2-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 27 | Q4D3W2_ROU | ROU | n/a | 72193889 | CHEMBL3990077 | 5-{2-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 28 | Q4D3W2_RRO | RRO | n/a | 95774 | n/a | 5-bromo-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 29 | Q4D3W2_SIN | SIN | DB00139 | 1110;21952380; | CHEMBL576 | SUCCINIC ACID | n/a | |
| 30 | Q4D3W2_VRO | VRO | n/a | 72187567 | CHEMBL3990078 | 5-[2-(4-methoxyphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 31 | Q4D3W2_W6Y | W6Y | n/a | 73010355 | CHEMBL3990529 | 5-[2-(5-carboxynaphthalen-2-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 32 | Q4D3W2_W70 | W70 | n/a | 73010356 | CHEMBL3990117 | 2,6-dioxo-5-[2-(4-phenoxyphenyl)ethyl]-1,2,3,6- tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 33 | Q4D3W2_W73 | W73 | n/a | 73010359 | CHEMBL3991296 | 2,6-dioxo-5-[2-(phenanthren-9-yl)ethyl]-1,2,3,6- tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 34 | Q4D3W2_W74 | W74 | n/a | 73010360 | CHEMBL3990946 | 2,6-dioxo-5-{2-[4-(trifluoromethoxy)phenyl]ethyl}-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 35 | Q4D3W2_W75 | W75 | n/a | 73010361 | CHEMBL3990712 | 5-[2-(3,5-dimethoxyphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 36 | Q4D3W2_W76 | W76 | n/a | 73010362 | CHEMBL3990766 | 5-[2-(3-methoxyphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 37 | Q4D3W2_W7A | W7A | n/a | 73010357 | CHEMBL3990960 | 2,6-dioxo-5-[2-(4-phenylphenyl)ethyl]-1,2,3,6- tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 38 | Q4D3W2_W7B | W7B | n/a | 73010358 | CHEMBL3990337 | 5-[2-(naphthalen-1-yl)ethyl]-2,6-dioxo-1,2,3,6- tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 39 | Q4D3W2_W7C | W7C | n/a | 73010363 | CHEMBL3990559 | 5-[2-(5-methoxynaphthalen-2-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 40 | Q4D3W2_W7D | W7D | n/a | 73010364 | CHEMBL3991297 | 5-[2-(8-methoxynaphthalen-2-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 41 | Q4D3W2_W7F | W7F | n/a | 73010365 | CHEMBL3990625 | 5-[2-(7-methoxynaphthalen-1-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 42 | Q4D3W2_W7G | W7G | n/a | 73010366 | CHEMBL3991295 | 5-[2-(2-methoxyphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 43 | Q4D3W2_W7H | W7H | n/a | 73010367 | CHEMBL3991249 | 5-[2-(naphthalen-2-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 44 | Q4D3W2_W7I | W7I | n/a | 73010368 | CHEMBL3991403 | 5-[2-(3-methoxynaphthalen-2-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 45 | Q4D3W2_W7J | W7J | n/a | 73010369 | CHEMBL3991052 | 5-[2-(6-carboxynaphthalen-2-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 46 | Q4D3W2_W7K | W7K | n/a | 73010370 | CHEMBL3991385 | 5-[2-(3,6-dimethoxynaphthalen-2-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 47 | Q4D3W2_W7L | W7L | n/a | 73010371 | CHEMBL3990284 | 5-[2-(6-methoxynaphthalen-1-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 48 | Q4D3W2_W7M | W7M | n/a | 73010372 | CHEMBL3990080 | 5-{2-[6-(methoxycarbonyl)naphthalen-2-yl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 49 | Q4D3W2_W7N | W7N | n/a | 73010373 | CHEMBL3990626 | 5-(2-{6-[(2-hydroxyethyl)carbamoyl]naphthalen-2-yl}ethyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 50 | Q4D3W2_W7O | W7O | n/a | 73010374 | CHEMBL3990355 | 5-[2-(3-carboxyphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 51 | Q4D3W2_W7P | W7P | n/a | 73010375 | CHEMBL3990818 | 5-[2-(4-carboxyphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 52 | Q4D3W2_W7Q | W7Q | n/a | 73010376 | CHEMBL3990159 | 5-{2-[1-(tert-butoxycarbonyl)-2,3-dihydro-1H-indol-5-yl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 53 | Q4D3W2_W83 | W83 | n/a | 73437557 | CHEMBL3991404 | 5-{2-[7-(methoxymethoxy)naphthalen-2-yl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 54 | Q4D3W2_W85 | W85 | n/a | 73167555 | CHEMBL3990251 | 5-{2-[3-(methoxycarbonyl)phenyl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 55 | Q4D3W2_W86 | W86 | n/a | 73167556 | CHEMBL3991171 | 5-{4-[4-(methoxycarbonyl)phenyl]butyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 56 | Q4D3W2_W87 | W87 | n/a | 73437558 | CHEMBL3990285 | 5-{4-[5-(methoxycarbonyl)naphthalen-2-yl]butyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 57 | Q4D3W2_W88 | W88 | n/a | 73167557 | CHEMBL3990161 | 5-[4-(6-carboxynaphthalen-2-yl)butyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 58 | Q4D3W2_W8Z | W8Z | n/a | 73167554 | CHEMBL3991250 | 5-{2-[3-(methoxymethoxy)naphthalen-2-yl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 59 | Q4D3W2_WRO | WRO | n/a | 71819696 | CHEMBL3990140 | 2,6-dioxo-5-{2-[3-(trifluoromethyl)phenyl]ethyl}-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 60 | Q4D3W2_XRO | XRO | n/a | 71819698 | CHEMBL3990961 | 5-{2-[4-(cyanomethyl)phenyl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 61 | Q4D3W2_YRO | YRO | n/a | 71816171 | n/a | 5-(3,3-dimethylbutyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 62 | Q4D3W2_ZRO | ZRO | n/a | 72187568 | CHEMBL3991294 | 2,6-dioxo-5-{2-[4-(trifluoromethyl)phenyl]ethyl}-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | n/a | |
| 63 | Q4D3W2_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a |