Gene name: DFR1
Protein name: Dihydrofolate reductase (EC
List of molecules and drugs that interact with protein Q5A5E0
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q5A5E0_06U | 06U | n/a | 56955942 | CHEMBL4483572 | 6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine | n/a | |
| 2 | Q5A5E0_14Q | 14Q | n/a | 71296042 | n/a | 5-{3-[3-(1,3-benzodioxol-5-yl)-5-methoxyphenyl]prop-1-yn-1-yl}-6-ethylpyrimidine-2,4-diamine | n/a | |
| 3 | Q5A5E0_53S | 53S | DB07141 | 44144378 | CHEMBL575218 | 5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine | n/a | |
| 4 | Q5A5E0_55V | 55V | DB07153 | 25187896 | CHEMBL1230365 | 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine | n/a | |
| 5 | Q5A5E0_GLY | GLY | DB00145 | 750;5257127; | CHEMBL773 | GLYCINE | n/a | |
| 6 | Q5A5E0_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 7 | Q5A5E0_N22 | N22 | DB08234 | 25058133 | CHEMBL485961 | 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine | n/a | |
| 8 | Q5A5E0_NDP | NDP | DB02338 | 5884;134821689; | CHEMBL407009 | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | n/a | |
| 9 | Q5A5E0_QLR | QLR | n/a | 45482254 | CHEMBL574741 | 6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)pent-1-yn-1-yl]pyrimidine-2,4-diamine | n/a |