Gene name: Enpp2
Protein name: Autotaxin (EC 3.1.4.39)
List of molecules and drugs that interact with protein Q64610
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q64610_4I0 | 4I0 | n/a | n/a | n/a | 2-[[2-ethyl-6-[4-[2-[(3~{R})-3-fluoranylpyrrolidin-1-yl]-2-oxidanylidene-ethyl]piperazin-1-yl]imidazo[1,2-a]pyridin-3-yl]-methyl-amino]-4-(4-fluorophenyl)-2,3-dihydro-1,3-thiazole-5-carbonitrile | n/a | |
| 2 | Q64610_5D5 | 5D5 | DB08834 | 9848818 | CHEMBL272427 | 2-{[(3alpha,5beta,7alpha,8alpha,14beta,17alpha)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid | n/a | |
| 3 | Q64610_5JK | 5JK | n/a | 107722 | CHEMBL497207 | 7alpha-hydroxycholesterol | n/a | |
| 4 | Q64610_5K9 | 5K9 | n/a | n/a | n/a | (9~{R},10~{a}~{S})-6,6,9-trimethyl-3-pentyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol | n/a | |
| 5 | Q64610_6ZM | 6ZM | n/a | 121488120 | CHEMBL4588676 | 1-{2-[(2,3-dihydro-1H-inden-2-yl)amino]-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl}ethan-1-one | n/a | |
| 6 | Q64610_6ZN | 6ZN | n/a | 121488121 | CHEMBL4549771 | 6-(3-{2-[(2,3-dihydro-1H-inden-2-yl)amino]-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl}propanoyl)-1,3-benzoxazol-2(3H)-one | n/a | |
| 7 | Q64610_6ZO | 6ZO | n/a | 25265312 | CHEMBL3186509 | (3,5-dichlorophenyl)methyl 4-[3-oxo-3-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)propyl]piperazine-1-carboxylate | n/a | |
| 8 | Q64610_72P | 72P | n/a | 56837805 | CHEMBL4073215 | 3-(6-chloranyl-2-methyl-1-phenyl-indol-3-yl)sulfanylbenzoic acid | n/a | |
| 9 | Q64610_7C8 | 7C8 | n/a | 129318946 | CHEMBL4085570 | [3,5-bis(chloranyl)phenyl]methyl 4-[(4~{R})-4-[(3~{R},5~{S},7~{S},8~{R},9~{S},10~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-3,7-bis(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentyl]piperazine-1-carboxylate | n/a | |
| 10 | Q64610_7CF | 7CF | n/a | 129318948 | CHEMBL4062929 | [3,5-bis(chloranyl)phenyl]methyl (3~{R})-3-[[(4~{R})-4-[(3~{R},5~{S},7~{S},8~{R},9~{S},10~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-3,7-bis(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]pyrrolidine-1-carboxylate | n/a | |
| 11 | Q64610_7CR | 7CR | n/a | 129318947 | n/a | [3,5-bis(chloranyl)phenyl]methyl 4-[(3~{R})-3-oxidanyl-3-(2-oxidanylidene-3~{H}-1,3-benzoxazol-6-yl)propyl]piperazine-1-carboxylate | n/a | |
| 12 | Q64610_7CW | 7CW | n/a | 129318949 | CHEMBL4105619 | [3,5-bis(chloranyl)phenyl]methyl ~{N}-[2-[[(4~{R})-4-[(3~{R},5~{S},7~{S},8~{R},9~{S},10~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-3,7-bis(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethyl]carbamate | n/a | |
| 13 | Q64610_7NB | 7NB | DB15403 | 90420193 | CHEMBL3828074 | 2-[[2-ethyl-8-methyl-6-[4-[2-(3-oxidanylazetidin-1-yl)-2-oxidanylidene-ethyl]piperazin-1-yl]imidazo[1,2-a]pyridin-3-yl]-methyl-amino]-4-(4-fluorophenyl)-1,3-thiazole-5-carbonitrile | n/a | |
| 14 | Q64610_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 15 | Q64610_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 16 | Q64610_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 17 | Q64610_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 18 | Q64610_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 19 | Q64610_I8K | I8K | n/a | n/a | n/a | [4-[1-[(4~{R})-4-[(3~{R},5~{S},7~{S},8~{R},9~{S},10~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-3,7-bis(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentanoyl]piperidin-4-yl]oxyphenyl]-bis(oxidanyl)-$l^{4}-borane | n/a | |
| 20 | Q64610_IA0 | IA0 | n/a | 166451601 | n/a | [(2~{S},4~{R})-4-[2-[(3,5-dimethylphenyl)amino]-5,7-dihydropyrrolo[3,4-d]pyrimidin-6-yl]-2-methyl-piperidin-1-yl]-(6-fluoranyl-1~{H}-benzotriazol-5-yl)methanone | n/a | |
| 21 | Q64610_IOD | IOD | n/a | 30165 | n/a | IODIDE ION | n/a | |
| 22 | Q64610_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 23 | Q64610_MAN | MAN | n/a | 185698 | CHEMBL365590 | alpha-D-mannopyranose | n/a | |
| 24 | Q64610_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 25 | Q64610_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 26 | Q64610_NKP | NKP | n/a | 49837858 | n/a | (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate | n/a | |
| 27 | Q64610_P6G | P6G | n/a | 17472 | CHEMBL1235082 | HEXAETHYLENE GLYCOL | n/a | |
| 28 | Q64610_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 29 | Q64610_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 30 | Q64610_SCN | SCN | n/a | 9322 | n/a | THIOCYANATE ION | n/a | |
| 31 | Q64610_TCI | TCI | DB00470 | 16078 | CHEMBL465 | (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol | n/a | |
| 32 | Q64610_TIJ | TIJ | n/a | 169410394 | n/a | 5,7-bis(oxidanyl)-2-[1-(phenylmethyl)indol-3-yl]chromen-4-one | n/a | |
| 33 | Q64610_YV1 | YV1 | n/a | 118555935 | n/a | (3,5-dichlorophenyl)methyl (3aR,8aS)-2-(1H-benzotriazole-5-carbonyl)octahydropyrrolo[3,4-d]azepine-6(1H)-carboxylate | n/a | |
| 34 | Q64610_YVS | YVS | n/a | 123431653 | n/a | [4-(trifluoromethoxy)phenyl]methyl (3aR,6aS)-5-(1H-benzotriazole-5-carbonyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate | n/a | |
| 35 | Q64610_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 36 | Q64610_SWH | SWH | n/a | 49837849 | n/a | {4-[(4-{(Z)-[3-(4-FLUOROBENZYL)-2,4-DIOXO-1,3-THIAZOLIDIN-5-YLIDENE]METHYL}PHENOXY)METHYL]PHENYL}(TRIHYDROXY)BORATE(1-) | n/a | |
| 37 | Q64610_T8R | T8R | n/a | 169410393 | n/a | 5,7-bis(oxidanyl)-2-(1-pentylindol-3-yl)chromen-4-one | n/a |