Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Q6P988 NOTUM_HUMAN
Gene name: NOTUM
Protein name: Palmitoleoyl-protein carboxylesterase NOTUM

List of molecules and drugs that interact with protein Q6P988

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 Q6P988_63Z 63Z n/a 62401451 CHEMBL5184800 [1-[4-chloranyl-3-(trifluoromethyl)phenyl]-1,2,3-triazol-4-yl]methanol n/a
2 Q6P988_657 657 DB00740 5070 CHEMBL744 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine n/a
3 Q6P988_7SQ 7SQ n/a 13106125 n/a 1-[4-chloranyl-3-(trifluoromethyl)phenyl]-1,2,3-triazole n/a
4 Q6P988_7T0 7T0 n/a 146438044 CHEMBL5178575 1-[2,4-bis(chloranyl)-3-(trifluoromethyl)phenyl]-1,2,3-triazole n/a
5 Q6P988_A6Z A6Z n/a 6926352 n/a 2-[4-(3-chlorophenyl)piperazin-1-ium-1-yl]ethanenitrile n/a
6 Q6P988_ASE ASE DB04275 903 CHEMBL33103 N-ACETYL SEROTONIN n/a IC50(nM) = 93600.0
7 Q6P988_AW7 AW7 n/a 2764389 n/a 2-[4-(1~{H}-pyrazol-3-yl)phenoxy]pyrimidine n/a
8 Q6P988_AWP AWP n/a 712045 n/a 1-cyclohexyl-3-(2-pyridin-4-ylethyl)urea n/a
9 Q6P988_AXV AXV n/a 96685 n/a 1~{H}-benzimidazol-2-ylcyanamide n/a
10 Q6P988_AY4 AY4 n/a 2804885 n/a 2,4-bis(fluoranyl)-6-(1~{H}-pyrazol-3-yl)phenol n/a
11 Q6P988_AYR AYR DB12582 638024 CHEMBL43185 (2E,4E)-5-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one n/a
12 Q6P988_B1A B1A n/a 789635 CHEMBL1543600 ~{N}-(4-phenylazanylphenyl)ethanamide n/a
13 Q6P988_B1J B1J n/a 2763878 CHEMBL1482091 [1-(4-chlorophenyl)-1,2,3-triazol-4-yl]methanol n/a
14 Q6P988_BEP BEP DB01244 445143 CHEMBL251075 1-ISOBUTOXY-2-PYRROLIDINO-3[N-BENZYLANILINO] PROPANE n/a
15 Q6P988_BP4 BP4 DB07477 3332 CHEMBL413965 biphenyl-4-ylacetic acid n/a
16 Q6P988_CFF CFF DB00201 2519 CHEMBL113 CAFFEINE n/a IC50(nM) = 18600.0
Kd(nM) = 85000.0
EC50(nM) = 45800.0
17 Q6P988_CL CL n/a 312 n/a CHLORIDE ION n/a
18 Q6P988_DMS DMS DB01093 679 CHEMBL504 DIMETHYL SULFOXIDE n/a
19 Q6P988_EDO EDO n/a 174 CHEMBL457299 1,2-ETHANEDIOL n/a
20 Q6P988_EJW EJW n/a 40475674 n/a (3-phenyl-1,2-oxazol-5-yl)methylazanium n/a
21 Q6P988_FNW FNW n/a 146425100 CHEMBL5173563 [1-[2,4-bis(chloranyl)-3-(trifluoromethyl)phenyl]-1,2,3-triazol-4-yl]methanol n/a
22 Q6P988_GOL GOL DB09462 753 CHEMBL692 GLYCEROL n/a
23 Q6P988_GQM GQM n/a 745280 n/a 5-methoxy-2-(1~{H}-pyrazol-3-yl)phenol n/a
24 Q6P988_GRV GRV n/a 757612 CHEMBL1381910 2-methyl-~{N}-(2-methylpropyl)imidazo[1,2-a]pyridine-3-carboxamide n/a
25 Q6P988_GVV GVV n/a 1234600 n/a ~{N}-(4-methyl-2-oxidanyl-phenyl)propanamide n/a
26 Q6P988_GW1 GW1 n/a 831977 CHEMBL1347703 (4-chloranyl-2-methyl-pyrazol-3-yl)-piperidin-1-yl-methanone n/a
27 Q6P988_HWH HWH n/a 699127 CHEMBL284521 ~{N}-[2-(5-fluoranyl-1~{H}-indol-3-yl)ethyl]ethanamide n/a
28 Q6P988_IOD IOD n/a 30165 n/a IODIDE ION n/a
29 Q6P988_JFP JFP n/a 3613666 CHEMBL4096653 N-(4-methyl-1,3-thiazol-2-yl)propanamide n/a
30 Q6P988_JFS JFS n/a 2763828 n/a [4-(1H-benzimidazol-1-yl)phenyl]methanol n/a
31 Q6P988_JFV JFV n/a 2763848 n/a methyl 2-(4-aminophenoxy)benzoate n/a
32 Q6P988_JGA JGA n/a 1526575 n/a N-ethyl-N'-(5-methyl-1,2-oxazol-3-yl)urea n/a
33 Q6P988_JH7 JH7 n/a 2818508 n/a 1-methyl-5-(phenylamino)-1,2-dihydro-3H-pyrazol-3-one n/a
34 Q6P988_JHJ JHJ n/a 694486 CHEMBL274733 N-(4-methoxyphenyl)-N'-pyridin-4-ylurea n/a
35 Q6P988_JV5 JV5 n/a 138115403 CHEMBL4439414 ~{N}-(1~{H}-benzotriazol-5-yl)-2-(2-methylphenoxy)ethanamide n/a
36 Q6P988_JV8 JV8 n/a 138115404 CHEMBL4441123 ~{N}-isoquinolin-6-yl-2-(2-methylphenoxy)ethanamide n/a
37 Q6P988_JVB JVB n/a 747195 CHEMBL4470075 2-(2-methylphenoxy)-~{N}-pyridin-3-yl-ethanamide n/a
38 Q6P988_K4Q K4Q n/a 155312307 n/a [(2~{S})-2-azanyl-3-oxidanylidene-propyl] octanoate n/a
39 Q6P988_LO5 LO5 n/a 795891 n/a 1-(1,3-benzodioxol-5-yl)-~{N}-[[(2~{R})-oxolan-2-yl]methyl]methanamine n/a
40 Q6P988_M9K M9K n/a 56932967 CHEMBL3774760 2-(6-chloranyl-7-cyclopropyl-thieno[3,2-d]pyrimidin-4-yl)sulfanylethanoic acid n/a
41 Q6P988_M9N M9N n/a 145946081 n/a 2-[[(4~{S})-5-chloranyl-6-methyl-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-4-yl]sulfanyl]ethanoic acid n/a
42 Q6P988_MJW MJW n/a 240548 n/a 2-phenylmethoxyaniline n/a
43 Q6P988_ML1 ML1 DB01065 896 CHEMBL45 N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide n/a IC50(nM) = 75400.0
44 Q6P988_MYZ MYZ n/a 5281119 CHEMBL456732 Myristoleic acid n/a
45 Q6P988_N9J N9J n/a 18907 CHEMBL1086896 benzyl hydroxycarbamate n/a
46 Q6P988_NA NA n/a 923 n/a SODIUM ION n/a
47 Q6P988_NAG NAG DB00141 24139 CHEMBL447878 2-acetamido-2-deoxy-beta-D-glucopyranose n/a
48 Q6P988_NCT NCT DB00184 89594 CHEMBL3 (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE n/a
49 Q6P988_NUM NUM n/a 1234046 n/a N-[2-(4-hydroxyphenyl)ethyl]pyridine-2-carboxamide n/a
50 Q6P988_NW7 NW7 n/a 842858 n/a 3-ethyl-5-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1,2-oxazole-4-carboxamide n/a
51 Q6P988_O1J O1J n/a 290301 CHEMBL3247413 (benzyloxy)acetic acid n/a
52 Q6P988_O3D O3D n/a 318460 n/a 4-[(furan-2-yl)methyl]-1lambda~6~,4-thiazinane-1,1-dione n/a
53 Q6P988_PAM PAM DB04257 445638 CHEMBL453509 PALMITOLEIC ACID n/a
54 Q6P988_PJK PJK n/a 154585553 CHEMBL4637220 (3~{S})-1-[4-chloranyl-3-(trifluoromethyl)phenyl]pyrrolidine-3-carboxylic acid n/a
55 Q6P988_PO4 PO4 DB14523 1061 n/a PHOSPHATE ION n/a
56 Q6P988_PQH PQH n/a 11769371 CHEMBL4644620 2-methyl-5-(trifluoromethyl)-1~{H}-pyrrole-3-carboxylic acid n/a
57 Q6P988_PQK PQK n/a 2776579 CHEMBL1577069 1-cyclopropyl-2,5-dimethyl-pyrrole-3-carboxylic acid n/a
58 Q6P988_PQT PQT n/a 97013871 n/a (3~{R})-1-(2-chlorophenyl)pyrrolidine-3-carboxylic acid n/a
59 Q6P988_PQZ PQZ n/a 16788534 CHEMBL4647574 1-(cyclopropylmethyl)-2,5-dimethyl-pyrrole-3-carboxylic acid n/a
60 Q6P988_PUE PUE n/a 28875696;51605800; n/a (3~{R})-1-phenylpyrrolidine-3-carboxylic acid n/a
61 Q6P988_PZ8 PZ8 n/a 16228326 CHEMBL4645532 1-(3-chlorophenyl)-2,5-dimethyl-pyrrole-3-carboxylic acid n/a
62 Q6P988_QL5 QL5 n/a 821673 CHEMBL1456302 (2,5-dimethylphenyl) pyridine-4-carboxylate n/a
63 Q6P988_QR2 QR2 n/a 146425072 CHEMBL4788846 5-[4-chloranyl-3-(trifluoromethyl)phenyl]-3~{H}-1,3,4-oxadiazol-2-one n/a
64 Q6P988_RC6 RC6 n/a 69558542 CHEMBL5397202 1-(4-chloranyl-2,3-dihydroindol-1-yl)ethanone n/a
65 Q6P988_RCU RCU n/a 166001314 n/a ethyl 4-[5-chloranyl-4-(trifluoromethyl)-2,3-dihydroindol-1-yl]-4-oxidanylidene-butanoate n/a
66 Q6P988_RD9 RD9 n/a 166001315 n/a methyl 4-oxidanylidene-4-[4-(trifluoromethyl)-2,3-dihydroindol-1-yl]butanoate n/a
67 Q6P988_RDO RDO n/a 166001316 n/a ethyl 4-oxidanylidene-4-[4-(trifluoromethyl)-2,3-dihydroindol-1-yl]butanoate n/a
68 Q6P988_REH REH n/a 127270027 n/a 1-(4-fluoranylspiro[2~{H}-indole-3,1'-cyclobutane]-1-yl)ethanone n/a
69 Q6P988_RFO RFO n/a 166001317 n/a 1-(4-chloranylindol-1-yl)-2-methoxy-ethanone n/a
70 Q6P988_RG0 RG0 n/a 166001318 CHEMBL5431852 1-[5-chloranyl-4-(trifluoromethyl)-2,3-dihydroindol-1-yl]ethanone n/a
71 Q6P988_RGO RGO n/a 166001319 n/a (3~{a}~{S})-2,2-bis(fluoranyl)-3~{a},4-dihydro-3~{H}-pyrrolo[1,2-a]indol-1-one n/a
72 Q6P988_RGU RGU n/a 166001320 n/a (3~{a}~{R})-2,3,3~{a},4-tetrahydropyrrolo[1,2-a]indol-1-one n/a
73 Q6P988_RIQ RIQ n/a 166001321 CHEMBL5397552 1-[4,5-bis(chloranyl)-2,3-dihydroindol-1-yl]ethanone n/a
74 Q6P988_RIX RIX n/a 166001322 n/a methyl 2-(4-chloranylindol-1-yl)-2-oxidanylidene-ethanoate n/a
75 Q6P988_RJ0 RJ0 n/a 23317889 CHEMBL4570581 1-(2,3-dihydroindol-1-yl)prop-2-en-1-one n/a
76 Q6P988_RL6 RL6 n/a 166001323 n/a 1-[3,4-bis(chloranyl)-5-methyl-indol-1-yl]ethanone n/a
77 Q6P988_ROA ROA DB16865 5281792 CHEMBL324842 (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid n/a
78 Q6P988_RRI RRI n/a 27673 CHEMBL3274978 1-indol-1-ylethanone n/a
79 Q6P988_RUY RUY n/a 653935 CHEMBL1330631 4-(piperidin-1-yl)-1,2,5-oxadiazol-3-amine n/a
80 Q6P988_RW8 RW8 n/a 667795 CHEMBL5084693 methyl 4-(2,3-dihydroindol-1-yl)-4-oxidanylidene-butanoate n/a
81 Q6P988_RYM RYM n/a 863558 n/a 4-(benzimidazol-1-ylmethyl)benzenecarbonitrile n/a
82 Q6P988_S1V S1V n/a 2756286 n/a 1-ethanoylpiperidine-4-carbonitrile n/a
83 Q6P988_S4V S4V n/a 752150 n/a ~{N}2-pyridin-2-ylbenzene-1,2-diamine n/a
84 Q6P988_SFY SFY DB00891 5336 CHEMBL700 4-amino-N-(pyridin-2-yl)benzenesulfonamide n/a
85 Q6P988_SO4 SO4 DB14546 1117 n/a SULFATE ION n/a
86 Q6P988_TB5 TB5 n/a 882019 CHEMBL1496177 4-(4-pyrrol-1-ylphenyl)morpholine n/a
87 Q6P988_TE5 TE5 n/a 676910 CHEMBL1415245 4-methoxy-6-phenyl-pyrimidin-2-amine n/a
88 Q6P988_TE8 TE8 n/a 765737 n/a (2~{R})-2-(4-phenylphenoxy)propanoic acid n/a
89 Q6P988_TEH TEH n/a 833616 CHEMBL1468944 4-(2-phenoxyethanoyl)piperazin-2-one n/a
90 Q6P988_TEK TEK n/a 1111771 CHEMBL1572228 ~{N}-(1-ethylbenzimidazol-2-yl)ethanamide n/a
91 Q6P988_TEP TEP DB00277 2153 CHEMBL190 THEOPHYLLINE n/a Kd(nM) = 6800000.0
92 Q6P988_TEZ TEZ n/a 591904 CHEMBL1308822 N-(2,1,3-Benzothiadiazol-5-yl)acetamide n/a
93 Q6P988_U2Q U2Q n/a 265630 CHEMBL1742002 2-[(3-Nitro-2-pyridyl)thio]acetic acid n/a
94 Q6P988_U2T U2T n/a 2743180 CHEMBL1306063 3-(4-~{tert}-butylphenyl)-1,2,4-oxadiazole-5-carbohydrazide n/a
95 Q6P988_U2W U2W n/a 2782329;86280330; n/a 4,5-bis(chloranyl)-3-nitro-1~{H}-pyridazin-6-one n/a
96 Q6P988_U35 U35 DB00177 60846 CHEMBL1069 (2~{S})-3-methyl-2-[pentanoyl-[[4-[2-(2~{H}-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid n/a
97 Q6P988_U3K U3K n/a 782822 n/a ~{N}-methyl-~{N}-[(5-methylfuran-2-yl)methyl]-1-phenyl-methanamine n/a
98 Q6P988_U3Q U3Q n/a 12565473 n/a 1-Naphthalenepentanoic acid n/a
99 Q6P988_U3T U3T n/a 53741002 n/a 6-(2-prop-2-ynoxyphenyl)hexanoic acid n/a
100 Q6P988_U3W U3W n/a 4124851 CHEMBL284861 2-methyl-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione n/a
101 Q6P988_U4K U4K n/a 1115922 CHEMBL1727684 2-isoquinolin-1-ylsulfanylethanoic acid n/a
102 Q6P988_U4T U4T n/a 695450 CHEMBL1421818 4H,5H-naphtho[1,2-b]thiophene-2-carboxylic acid n/a
103 Q6P988_U58 U58 n/a 723893 n/a 3-(quinazolin-4-ylsulfanyl)propanoic acid n/a
104 Q6P988_U5B U5B n/a 2431658 n/a 2-(1,2-dihydroacenaphthylen-5-ylsulfanyl)ethanoic acid n/a
105 Q6P988_U5E U5E n/a 1490444 CHEMBL1560359 N-methyl-4,5-dihydrobenzo[g]benzothiophene-2-carboxamide n/a
106 Q6P988_U5H U5H n/a 854019 CHEMBL578211 (5~{S})-1-methyl-5-pyridin-3-yl-pyrrolidin-2-one n/a
107 Q6P988_U5T U5T n/a 97993477 n/a (4~{E})-2-(3,4-dimethylphenyl)-4-[(1-methylpyrazol-4-yl)methylidene]-1,3-oxazol-5-one n/a
108 Q6P988_U5Z U5Z n/a 2782955 n/a 1-[(4-fluorophenyl)amino]thiourea n/a
109 Q6P988_U62 U62 n/a 2113888 CHEMBL1499110 4~{H}-thieno[3,2-c]chromene-2-carboxylic acid n/a
110 Q6P988_U65 U65 n/a 3588737 CHEMBL1352800 methyl 3~{a},4-dihydro-3~{H}-thieno[3,2-c]chromene-2-carboxylate n/a
111 Q6P988_UR4 UR4 n/a 831456 n/a 2-methoxy-N-(4-phenyl-1,3-thiazol-2-yl)acetamide n/a
112 Q6P988_WKA WKA n/a 585399 n/a N-(2,1,3-benzoxadiazol-4-yl)acetamide n/a
113 Q6P988_WNA WNA n/a 834605 CHEMBL1450237 1-methyl-N-[(2-methylphenyl)methyl]-1H-tetrazol-5-amine n/a
114 Q6P988_YI6 YI6 n/a 78631 n/a 2-(4-ethoxyphenyl)ethanoic acid n/a
115 Q6P988_SQW SQW n/a 156587331 n/a propan-2-yl 4-indol-1-yl-4-oxidanylidene-butanoate n/a
116 Q6P988_SRH SRH n/a 2140509 CHEMBL5078750 ethyl 4-(2,3-dihydroindol-1-yl)-4-oxidanylidene-butanoate n/a
117 Q6P988_SRK SRK n/a 730429 CHEMBL357516 4-(2,3-dihydroindol-1-yl)-4-oxidanylidene-butanoic acid n/a
118 Q6P988_SRQ SRQ n/a 156587332 CHEMBL5072324 2,2-bis(fluoranyl)ethyl 4-(2,3-dihydroindol-1-yl)-4-oxidanylidene-butanoate n/a
119 Q6P988_SSQ SSQ n/a 162368323 CHEMBL5078474 6-((2-chlorophenyl)thio)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one n/a
120 Q6P988_SSW SSW n/a 162368324 CHEMBL5078659 6-((3-(trifluoromethoxy)phenyl)thio)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one n/a
121 Q6P988_STK STK n/a 162368325 CHEMBL5079105 3-(3-chlorophenyl)sulfanyl-1$l^{4},2,7,8-tetrazabicyclo[4.3.0]nona-1(6),2,4,7-tetraen-9-one n/a
122 Q6P988_SUQ SUQ n/a 162368326 CHEMBL5079298 6-((4-chlorophenyl)thio)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one n/a
123 Q6P988_SUT SUT n/a 162368327 CHEMBL5076852 6-(m-tolylthio)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one n/a
124 Q6P988_SWQ SWQ n/a 162394532 CHEMBL5092063 6-(3-methylsulfanylphenyl)sulfanyl-2~{H}-[1,2,4]triazolo[4,3-b]pyridazin-3-one n/a
125 Q6P988_SWT SWT n/a 50743655 CHEMBL5079507 6-(4-methylphenyl)sulfanyl-2~{H}-[1,2,4]triazolo[4,3-b]pyridazin-3-one n/a
126 Q6P988_SXQ SXQ n/a 162394533 CHEMBL5070478 3-(3,4-dichlorophenyl)sulfanyl-1$l^{4},2,7,8-tetrazabicyclo[4.3.0]nona-1(6),2,4,7-tetraen-9-one n/a
127 Q6P988_T1W T1W n/a 669647 n/a [(2~{S})-2-methylpiperidin-1-yl]-morpholin-4-yl-methanone n/a
128 Q6P988_T1Z T1Z n/a 1475797 CHEMBL1823290 [1-(3,4-dichlorophenyl)-1,2,3-triazol-4-yl]methanol n/a
129 Q6P988_T2E T2E n/a 808768 n/a 5-azanyl-2-(pyridin-3-ylmethylamino)benzoic acid n/a
130 Q6P988_T2H T2H n/a 879253 n/a 5-(3-ethoxyphenyl)-1,3,4-thiadiazol-2-amine n/a
131 Q6P988_T3N T3N n/a 101437 n/a 2-(4-acetamidophenoxy)ethanoic acid n/a
132 Q6P988_T3T T3T n/a 1080494 CHEMBL1340204 1-(1,3-benzodioxol-5-yl)-~{N}-(pyridin-2-ylmethyl)methanamine n/a
133 Q6P988_T9B T9B n/a 898585 n/a (2S)-N-(4-Methoxybenzyl)tetrahydrofuran-2-carboxamide n/a
134 Q6P988_T9K T9K n/a 1506457 n/a methyl 2-(4-cyanophenoxy)ethanoate n/a
135 Q6P988_T9Q T9Q n/a 836024 n/a N-Benzyl-2-methoxyacetamide n/a
136 Q6P988_T9W T9W n/a 5190948 n/a 2-[4-(2,5-Dioxopyrrolidin-1-yl)phenoxy]acetate n/a
137 Q6P988_T9Z T9Z n/a 6928333 n/a 2-(morpholin-4-ium-4-ylmethyl)naphthalen-1-ol n/a
138 Q6P988_TAH TAH n/a 935766 CHEMBL1587693 2-(benzyloxy)benzohydrazide n/a