Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Q76353 Q76353_HV1
Gene name:
Protein name: Integrase

List of molecules and drugs that interact with protein Q76353

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 Q76353_100 100 DB03118 n/a CHEMBL473489 1-(5-CHLOROINDOL-3-YL)-3-HYDROXY-3-(2H-TETRAZOL-5-YL)-PROPENONE n/a
2 Q76353_1PE 1PE n/a 62551 CHEMBL1229766 PENTAETHYLENE GLYCOL n/a
3 Q76353_1TD 1TD n/a 16413298 n/a 3-[(E)-(2-oxidanylidene-1H-indol-3-ylidene)methyl]benzoic acid n/a
4 Q76353_2SS 2SS n/a 71816178 n/a (2S)-6-[[[2-(cyclobutylmethylcarbamoyl)phenyl]methyl-prop-2-enyl-amino]methyl]-2-(3-hydroxy-3-oxopropyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
5 Q76353_3GM 3GM n/a 71816186 n/a (2s)-6-[[(1r,2s)-2-(4-azanylbutanoylamino)-2,3-dihydro-1h-inden-1-yl]methyl]-2-(3-hydroxy-3-oxopropyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
6 Q76353_4D2 4D2 n/a 72551598 n/a 5-[(2S)-4-methyl-2-[(pyridin-3-ylcarbonylamino)methyl]pentyl]-1,3-benzodioxole-4-carboxylic acid n/a
7 Q76353_4VW 4VW n/a 72551593 n/a 5-[(2S)-2-[[(4-aminophenyl)carbonylamino]methyl]-4-methyl-pentyl]-1,3-benzodioxole-4-carboxylic acid n/a
8 Q76353_5EY 5EY n/a 71819712 n/a (3R)-3-(3-hydroxy-3-oxopropyl)-6-[(E)-[(2R)-2-oxidanyl-2,3-dihydroinden-1-ylidene]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
9 Q76353_6I2 6I2 n/a 164607196 n/a {2-[(3-{[4-(2-{[(3-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}phenyl)methyl]amino}ethyl)piperazin-1-yl]methyl}phenyl)ethynyl]-5-methyl-1-benzofuran-3-yl}acetic acid n/a
10 Q76353_6W6 6W6 n/a 122164608 n/a 3-[2,5-bis(chloranyl)pyrrol-1-yl]thiophene-2-carboxylic acid n/a
11 Q76353_6XI 6XI n/a 2776534 n/a 3-pyrrol-1-ylthiophene-2-carboxylic acid n/a
12 Q76353_723 723 n/a 921795 CHEMBL1230532 (6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)acetic acid n/a
13 Q76353_7NV 7NV n/a 71819715 n/a 5-[[[(1S)-2-(butylamino)-2-oxidanylidene-1-phenyl-ethyl]carbamoyl-methyl-amino]methyl]-1,3-benzodioxole-4-carboxylic acid n/a
14 Q76353_7SK 7SK n/a 122177120 n/a (2S)-tert-butoxy[3-(3,4-dihydro-2H-1-benzopyran-6-yl)-1-methyl-1H-indol-2-yl]acetic acid n/a
15 Q76353_8P3 8P3 n/a 43473224 n/a 2-[(2-oxo-2,3-dihydro-1H-indol-1-yl)methyl]benzoic acid n/a
16 Q76353_976 976 n/a 45281242 CHEMBL1230654 (2S)-2-(6-chloro-2-methyl-4-phenylquinolin-3-yl)pentanoic acid n/a
17 Q76353_9I4 9I4 n/a 165412408 n/a (2-{[3-({4-[2-(3-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}benzamido)ethyl]piperazin-1-yl}methyl)phenyl]ethynyl}-5-methyl-1-benzofuran-3-yl)acetic acid n/a
18 Q76353_9NS 9NS n/a 71816179 n/a (2S)-6-[[[2-(furan-2-ylmethylcarbamoyl)phenyl]methyl-prop-2-enyl-amino]methyl]-2-(3-hydroxy-3-oxopropyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
19 Q76353_9PA 9PA n/a 72551597 n/a 5-[(2S)-2-{[(5-aminopentanoyl)amino]methyl}-4-methylpentyl]-1,3-benzodioxole-4-carboxylic acid n/a
20 Q76353_ACT ACT DB14511 175 n/a ACETATE ION n/a
21 Q76353_ACY ACY DB03166 176;21980959;160748163; CHEMBL539 ACETIC ACID n/a
22 Q76353_ARS ARS n/a 23969 CHEMBL1231052 ARSENIC n/a
23 Q76353_B0T B0T n/a 71819709 n/a (2S)-6-[[[2-[[(2S)-butan-2-yl]carbamoyl]phenyl]methyl-methyl-amino]methyl]-2-(3-hydroxy-3-oxopropyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
24 Q76353_C5Q C5Q n/a 72201004 n/a 5-(1H-indol-3-ylmethyl)-1,3-benzodioxole-4-carboxylic acid n/a
25 Q76353_CA CA n/a 271 n/a CALCIUM ION n/a
26 Q76353_CAC CAC n/a 167250 n/a CACODYLATE ION n/a
27 Q76353_CBJ CBJ n/a 51049650 n/a 6-[(5-bromo-2,3-dioxo-2,3-dihydro-1H-indol-1-yl)methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
28 Q76353_CD CD n/a 31193 n/a CADMIUM ION n/a
29 Q76353_CD9 CD9 n/a 51049649 n/a 5-[(6-chloro-2-oxo-2,3-dihydro-1H-indol-1-yl)methyl]-1,3-benzodioxole-4-carboxylic acid n/a
30 Q76353_CDQ CDQ n/a 51049647 n/a 6-[(5-chloro-2-oxo-2,3-dihydro-1H-indol-1-yl)methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
31 Q76353_CIW CIW n/a 51049646 n/a 5-[(5-chloro-2-oxo-2,3-dihydro-1H-indol-1-yl)methyl]-1,3-benzodioxole-4-carboxylic acid n/a
32 Q76353_CL CL n/a 312 n/a CHLORIDE ION n/a
33 Q76353_CWU CWU n/a 72193904 n/a 5-[[(1S,2R)-2-oxidanyl-2,3-dihydro-1H-inden-1-yl]methyl]-1,3-benzodioxole-4-carboxylic acid n/a
34 Q76353_D0T D0T n/a 71816180 n/a (2S)-2-(3-hydroxy-3-oxopropyl)-6-[[methyl-[[2-[(phenylmethyl)carbamoyl]phenyl]methyl]amino]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
35 Q76353_DLU DLU DB08930 54726191 CHEMBL1229211 (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide n/a
36 Q76353_DMS DMS DB01093 679 CHEMBL504 DIMETHYL SULFOXIDE n/a
37 Q76353_E4F E4F n/a 72551591 n/a 5-[[(1R,2S)-2-(5-azanylpentanoylamino)-2,3-dihydro-1H-inden-1-yl]methyl]-1,3-benzodioxole-4-carboxylic acid n/a
38 Q76353_EDO EDO n/a 174 CHEMBL457299 1,2-ETHANEDIOL n/a
39 Q76353_EE2 EE2 n/a 71819711 n/a (2R)-2-(3-hydroxy-3-oxopropyl)-6-[(E)-[(2S)-2-oxidanyl-2,3-dihydroinden-1-ylidene]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
40 Q76353_FYM FYM n/a 72551600 n/a 2-methoxy-6-[[[6-[(4-methoxyphenyl)methylcarbamoyl]-1,3-benzodioxol-5-yl]methyl-methyl-amino]methyl]benzoic acid n/a
41 Q76353_G0T G0T n/a 71816181 n/a (2S)-2-(3-hydroxy-3-oxopropyl)-6-[[[2-[(4-methoxyphenyl)methylcarbamoyl]phenyl]methyl-methyl-amino]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
42 Q76353_GE7 GE7 n/a 44199169 n/a (2S)-tert-butoxy[2-methyl-4-(4-methylphenyl)quinolin-3-yl]acetic acid n/a
43 Q76353_GEI GEI n/a 118307857 CHEMBL5093378 (2S)-tert-butoxy[4-(4,4-dimethylpiperidin-1-yl)-5-{4-[2-(4-fluorophenyl)ethoxy]phenyl}-2,6-dimethylpyridin-3-yl]acetic acid n/a
44 Q76353_GOL GOL DB09462 753 CHEMBL692 GLYCEROL n/a
45 Q76353_H39 H39 n/a 72551596 n/a 5-[(2S)-4-methyl-2-{[(1H-pyrrol-3-ylacetyl)amino]methyl}pentyl]-1,3-benzodioxole-4-carboxylic acid n/a
46 Q76353_H75 H75 n/a 72206626 n/a 2-(4-bromophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3(2H)-one n/a
47 Q76353_HLR HLR n/a 2779749 n/a 1,2-benzoxazol-3-amine n/a
48 Q76353_IMV IMV n/a 51049645 CHEMBL1738817 5-[(2-oxo-2,3-dihydro-1H-indol-1-yl)methyl]-1,3-benzodioxole-4-carboxylic acid n/a
49 Q76353_IOD IOD n/a 30165 n/a IODIDE ION n/a
50 Q76353_IV2 IV2 n/a 1180481 n/a 5-chloranyl-4-methyl-1,3-benzothiazol-2-amine n/a
51 Q76353_IY7 IY7 n/a 72201001 n/a (2s)-6-[[(1r,2s)-2-(5-azanylpentanoylamino)-2,3-dihydro-1h-inden-1-yl]methyl]-2-(3-hydroxy-3-oxopropyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
52 Q76353_JDX JDX n/a 72551589 n/a 2-methoxy-6-[[[2-[(4-methoxyphenyl)methylcarbamoyl]phenyl]methyl-methyl-amino]methyl]benzoic acid n/a
53 Q76353_JNS JNS n/a 72706081 n/a 5-[(Z)-2-phenylethenyl]-1,3-benzodioxole-4-carboxylic acid n/a
54 Q76353_K1T K1T n/a 72706082 n/a 5-[(2S)-2-{[(4-aminobutanoyl)amino]methyl}-4-methylpentyl]-1,3-benzodioxole-4-carboxylic acid n/a
55 Q76353_K5Q K5Q n/a 137349630 n/a (2S)-6-[(E)-[(2E)-2-hydroxyimino-3H-inden-1-ylidene]methyl]-2-(3-hydroxy-3-oxopropyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
56 Q76353_KZD KZD n/a 163359806 CHEMBL5174467 (2S)-tert-butoxy[(4S)-7-(4,4-dimethylpiperidin-1-yl)-8-{4-[2-(4-fluorophenyl)ethoxy]phenyl}-2,5-dimethylimidazo[1,2-a]pyridin-6-yl]acetic acid n/a
57 Q76353_L0Y L0Y n/a 72551601 n/a 6-[[[2-(cyclohexylmethylcarbamoyl)phenyl]methyl-methyl-amino]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
58 Q76353_LOZ LOZ n/a 72187583 n/a 5-[[(1S,2R)-2-(4-azanylbutanoylamino)-2,3-dihydro-1H-inden-1-yl]methyl]-1,3-benzodioxole-4-carboxylic acid n/a
59 Q76353_LYS LYS DB00123 641599;5460926;24848423;162317967; n/a LYSINE n/a
60 Q76353_MG MG n/a 888 n/a MAGNESIUM ION n/a
61 Q76353_N44 N44 n/a 137349785 n/a 5-({[2-(benzylcarbamoyl)benzyl](prop-2-en-1-yl)amino}methyl)-1,3-benzodioxole-4-carboxylate n/a
62 Q76353_NA NA n/a 923 n/a SODIUM ION n/a
63 Q76353_NFW NFW n/a 71816184 n/a (2S)-6-[[[2-(furan-2-ylmethylcarbamoyl)phenyl]methyl-methyl-amino]methyl]-2-(3-hydroxy-3-oxopropyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
64 Q76353_NVU NVU n/a 301729 CHEMBL3792472 2-(1,2-benzoxazol-3-yl)ethanoic acid n/a
65 Q76353_NZL NZL n/a 72187584 n/a 5-[[(1S,2S)-2-(6-azanylhexanoylamino)-2,3-dihydro-1H-inden-1-yl]methyl]-1,3-benzodioxole-4-carboxylic acid n/a
66 Q76353_O20 O20 n/a 126573008 CHEMBL5177043 (2S)-tert-butoxy[(5M)-5-{2-[(2-chloro-6-methylphenyl)methyl]-1,2,3,4-tetrahydroisoquinolin-6-yl}-4-(4,4-dimethylpiperidin-1-yl)-2-methylpyridin-3-yl]acetic acid n/a
67 Q76353_O2N O2N n/a 57345916;72200742; CHEMBL3125908 5-{[(2-{[bis(4-methoxyphenyl)methyl]carbamoyl}benzyl)(prop-2-en-1-yl)amino]methyl}-1,3-benzodioxole-4-carboxylic acid n/a
68 Q76353_O3N O3N n/a 57345918 n/a (2S)-2-(2-carboxyethyl)-6-{[{2-[(cyclohexylmethyl)carbamoyl]benzyl}(prop-2-en-1-yl)amino]methyl}-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
69 Q76353_O4N O4N n/a 57345917;72200743; n/a 5-[[[2-[[(1S)-1-(4-METHOXYPHENYL)BUTYL]CARBAMOYL]PHENYL]METHYL-PROP-2-ENYL-AMINO]METHYL]-1,3-BENZODIOXOLE-4-CARBOXYLIC ACID n/a
70 Q76353_O5U O5U n/a 71816185 n/a (2R)-6-[[(1R,2S)-2-(6-azanylhexanoylamino)-2,3-dihydro-1H-inden-1-yl]methyl]-2-(3-hydroxy-3-oxopropyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
71 Q76353_OM1 OM1 n/a 137349844 n/a (4-CARBOXY-1,3-BENZODIOXOL-5-YL)METHYL-[[2-[(4-METHOXYPHENYL)METHYLCARBAMOYL]PHENYL]METHYL]AZANIUM n/a
72 Q76353_OM2 OM2 n/a 137349845 n/a (R)-[2-[[(2S)-BUTAN-2-YL]CARBAMOYL]PHENYL]METHYL-[(4-CARBOXY-1,3-BENZODIOXOL-5-YL)METHYL]-METHYL-AZANIUM n/a
73 Q76353_OM3 OM3 n/a 137349846 n/a (R)-(4-CARBOXY-1,3-BENZODIOXOL-5-YL)METHYL-[[2-(CYCLOHEXYLMETHYLCARBAMOYL)PHENYL]METHYL]-METHYL-AZANIUM n/a
74 Q76353_ONZ ONZ n/a 72193902 n/a 2-(1,3-benzodioxol-4-ylcarbonylamino)ethanoic acid n/a
75 Q76353_P03 P03 n/a 45281241 n/a 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol n/a
76 Q76353_PEG PEG n/a 8117 CHEMBL1235226 DI(HYDROXYETHYL)ETHER n/a
77 Q76353_PX3 PX3 n/a 70678408 n/a 5-[[[2-[(4-methoxyphenyl)methylcarbamoyl]phenyl]methyl-prop-2-enyl-amino]methyl]-1,3-benzodioxole-4-carboxylic acid n/a
78 Q76353_Q31 Q31 n/a 72551594 n/a 5-[(2S)-2-[[2-(1H-imidazol-4-yl)ethanoylamino]methyl]-4-methyl-pentyl]-1,3-benzodioxole-4-carboxylic acid n/a
79 Q76353_QCG QCG n/a 56929814 CHEMBL4454255 (2S)-tert-butoxy[7-(8-fluoro-5-methyl-3,4-dihydro-2H-1-benzopyran-6-yl)-5-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-6-yl]acetic acid n/a
80 Q76353_QCH QCH n/a 71816182 n/a (2S)-6-[[[2-(cyclohexylmethylcarbamoyl)phenyl]methyl-methyl-amino]methyl]-2-(3-hydroxy-3-oxopropyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
81 Q76353_QD6 QD6 n/a 168300968 n/a (2S)-tert-butoxy{4-(4-chlorophenyl)-2,6-dimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid n/a
82 Q76353_R2A R2A n/a 155387719 n/a (2-{[3-(4-{2-[(3-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}benzene-1-carbonyl)amino]ethyl}piperazine-1-carbonyl)phenyl]ethynyl}-5-methyl-1-benzofuran-3-yl)acetic acid n/a
83 Q76353_R7J R7J n/a 155490982 n/a [5-(3-fluorophenyl)-1-benzofuran-3-yl]acetic acid n/a
84 Q76353_RVN RVN n/a 72551595 n/a 5-[(E)-(2-oxidanylidene-1H-indol-3-ylidene)methyl]-1,3-benzodioxole-4-carboxylic acid n/a
85 Q76353_S3G S3G n/a 72551592 n/a 5-[(2S)-4-methyl-2-[(pyridin-4-ylcarbonylamino)methyl]pentyl]-1,3-benzodioxole-4-carboxylic acid n/a
86 Q76353_S8Y S8Y n/a 71819716 n/a 5-[[[(1R)-2-(tert-butylamino)-2-oxidanylidene-1-phenyl-ethyl]carbamoyl-methyl-amino]methyl]-1,3-benzodioxole-4-carboxylic acid n/a
87 Q76353_SO4 SO4 DB14546 1117 n/a SULFATE ION n/a
88 Q76353_THR THR DB00156 6288;6971019; CHEMBL291747 THREONINE n/a
89 Q76353_TTA TTA n/a 68178 n/a TETRAPHENYL-ARSONIUM n/a
90 Q76353_TTO TTO DB02086 5460502 n/a (3,4-DIHYDROXY-PHENYL)-TRIPHENYL-ARSONIUM n/a
91 Q76353_U2Z U2Z n/a 72193903 n/a [1-[2-(aminomethyl)phenyl]-5-methyl-pyrazol-3-yl]methanol n/a
92 Q76353_UJ6 UJ6 n/a 72187581 n/a 5-{[(3S)-2-oxo-2,3-dihydro-1H-indol-3-yl]methyl}-1,3-benzodioxole-4-carboxylic acid n/a
93 Q76353_V7H V7H n/a 72193901 n/a (2S)-2-(3-hydroxy-3-oxopropyl)-6-[[[2-[(phenylmethyl)carbamoyl]phenyl]methylamino]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
94 Q76353_VL4 VL4 n/a 71816183 n/a (2S)-6-[[[2-(cyclobutylmethylcarbamoyl)phenyl]methyl-methyl-amino]methyl]-2-(3-hydroxy-3-oxopropyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid n/a
95 Q76353_VXO VXO n/a 72551599 n/a 5-[(2S)-2-[[2-(1H-indol-3-yl)ethanoylamino]methyl]-4-methyl-pentyl]-1,3-benzodioxole-4-carboxylic acid n/a
96 Q76353_WOP WOP n/a 71819713 n/a 5-[[methyl-[[(1S)-2-oxidanylidene-1-phenyl-2-[(phenylmethyl)amino]ethyl]carbamoyl]amino]methyl]-1,3-benzodioxole-4-carboxylic acid n/a
97 Q76353_X0P X0P n/a 72551590 n/a 2-methoxy-6-[[[3-[(4-methoxyphenyl)methylcarbamoyl]naphthalen-2-yl]methyl-methyl-amino]methyl]benzoic acid n/a
98 Q76353_XFS XFS n/a 162369719 n/a 3-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}benzoic acid n/a
99 Q76353_YAV YAV n/a 162625306 n/a 2-[2-[2-[3-[2-[2-[2-[[3-[2-[3-(2-hydroxy-2-oxoethyl)-5-methyl-1-benzofuran-2-yl]ethynyl]phenyl]carbonylamino]ethoxy]ethoxy]ethylcarbamoyl]phenyl]ethynyl]-5-methyl-1-benzofuran-3-yl]ethanoic acid n/a
100 Q76353_ZSV ZSV n/a 78225670 n/a (R)-[(2S)-5-carboxy-2-(2-carboxyethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]methyl-[[2-[(4-methoxyphenyl)methylcarbamoyl]phenyl]methyl]-prop-2-enyl-azanium n/a
101 Q76353_ZSW ZSW n/a 137350217 n/a (R)-[2-[[(2R)-butan-2-yl]carbamoyl]phenyl]methyl-[[(2S)-5-carboxy-2-(2-carboxyethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]methyl]-prop-2-enyl-azanium n/a
102 Q76353_ZT0 ZT0 n/a 137350218 n/a (4-CARBOXY-1,3-BENZODIOXOL-5-YL)-N-{2-[(4-METHOXYBENZYL)CARBAMOYL]BENZYL}-N-METHYLMETHANAMINIUM n/a
103 Q76353_ZT2 ZT2 n/a 57345925 n/a 5-[(E)-(2-OXO-2,3-DIHYDRO-1H-INDEN-1-YLIDENE)METHYL]-1,3-BENZODIOXOLE-4-CARBOXYLIC ACID n/a
104 Q76353_ZT4 ZT4 n/a 137350219 n/a 5-{(E)-[(2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YLIDENE]METHYL}-1,3-BENZODIOXOLE-4-CARBOXYLIC ACID n/a