Gene name: STING1
Protein name: Stimulator of interferon
List of molecules and drugs that interact with protein Q86WV6
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q86WV6_1SY | 1SY | n/a | 71563406;135564529; | CHEMBL4465054 | cGAMP | n/a | |
| 2 | Q86WV6_1YC | 1YC | n/a | 71656176;135566854; | CHEMBL4435159 | 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one | n/a | |
| 3 | Q86WV6_1YE | 1YE | DB06235 | 123964 | CHEMBL71263 | (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid | n/a | |
| 4 | Q86WV6_2BA | 2BA | n/a | 11158091 | CHEMBL1229884 | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide | n/a | |
| 5 | Q86WV6_4UR | 4UR | n/a | 91808048;135567055; | CHEMBL4449197 | 3'2'-cGAMP | n/a | |
| 6 | Q86WV6_8SC | 8SC | n/a | 163359799 | n/a | 3'3'-c-(2'F,2'dA-isonucA)MP | n/a | |
| 7 | Q86WV6_98F | 98F | n/a | 165412407 | n/a | 9-[(1R,6R,8R,13E,15R,17R,18R)-17-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,16-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadec-13-en-8-yl]purin-6-amine | n/a | |
| 8 | Q86WV6_9UH | 9UH | n/a | 165368442 | n/a | (2R,5R,7R,8S,10R,12aR,14R,15R,15aS,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-2,10,15,16-tetrahydroxyoctahydro-2H,10H,12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione | n/a | |
| 9 | Q86WV6_9UR | 9UR | n/a | 165412409 | n/a | (2S,5R,7R,8R,10S,12aR,14R,15R,15aR,16R)-7-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-2,10,15,16-tetrahydroxyoctahydro-2H,10H,12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione | n/a | |
| 10 | Q86WV6_A8A | A8A | n/a | 167311775 | n/a | 4-[6-methoxy-5-[3-[[6-methoxy-2-(4-oxidanyl-4-oxidanylidene-butanoyl)-1-benzoselenophen-5-yl]oxy]propoxy]-1-benzoselenophen-2-yl]-4-oxidanylidene-butanoic acid | n/a | |
| 11 | Q86WV6_A9X | A9X | n/a | 164946677 | CHEMBL5219485 | (2R)-4-(5,6-dimethoxy-1-benzoselenophen-2-yl)-2-ethyl-4-oxidanylidene-butanoic acid | n/a | |
| 12 | Q86WV6_C2E | C2E | n/a | 5287531;6323195;135440063; | CHEMBL1231573 | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one) | n/a | |
| 13 | Q86WV6_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 14 | Q86WV6_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 15 | Q86WV6_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 16 | Q86WV6_GC0 | GC0 | n/a | 146435716 | n/a | (3S,4S)-4-(3-{5-carbamoyl-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-methoxy-1H-benzimidazol-1-yl}propyl)-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine-8-carboxamide | n/a | |
| 17 | Q86WV6_GD2 | GD2 | n/a | 147570332 | n/a | (3S,4S)-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-4-(prop-2-en-1-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine-8-carboxamide | n/a | |
| 18 | Q86WV6_GJF | GJF | n/a | n/a | n/a | (1~{R},3~{S},6~{R},8~{R},9~{R},10~{S},12~{S},15~{R},17~{R},18~{R})-8,17-bis(6-aminopurin-9-yl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecane-9,18-diol | n/a | |
| 19 | Q86WV6_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 20 | Q86WV6_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 21 | Q86WV6_K5P | K5P | n/a | 135393514 | CHEMBL4444823 | (3S,4S)-2-(4-tert-butylphenyl)-3-(4-methoxyphenyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid | n/a | |
| 22 | Q86WV6_K5S | K5S | n/a | 135393515 | CHEMBL4557373 | [(3S,4S)-2-(4-tert-butyl-3-chlorophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-7-fluoro-1-oxo-1,2,3,4-tetrahydroisoquinolin-4-yl]acetic acid | n/a | |
| 23 | Q86WV6_KWF | KWF | n/a | 165368568 | CHEMBL5189981 | 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{S},15~{R},17~{R},18~{R})-8-[4-azanyl-5-(4-naphthalen-2-ylphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]-3,9,12,18-tetrakis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-3~{H}-purin-6-one | n/a | |
| 24 | Q86WV6_KWO | KWO | n/a | 165368569 | CHEMBL5187347 | 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{S},15~{R},17~{R},18~{R})-8-[4-azanyl-5-(4-phenylphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]-3,9,12,18-tetrakis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-1~{H}-purin-6-one | n/a | |
| 25 | Q86WV6_KXD | KXD | n/a | 165368570 | CHEMBL5172826 | 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{S},15~{R},17~{R},18~{R})-8-[4-azanyl-5-[4-(naphthalen-1-yloxymethyl)phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]-3,9,12,18-tetrakis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-3~{H}-purin-6-one | n/a | |
| 26 | Q86WV6_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 27 | Q86WV6_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 28 | Q86WV6_OK6 | OK6 | n/a | 165368574 | CHEMBL5204143 | 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{S},15~{R},17~{R},18~{R})-8-(4-azanyl-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl)-3,9,12,18-tetrakis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-1~{H}-purin-6-one | n/a | |
| 29 | Q86WV6_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 30 | Q86WV6_PWB | PWB | n/a | n/a | n/a | 3',3'-c-[2'FdAMP-2'FdAM(PS)] | n/a | |
| 31 | Q86WV6_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 32 | Q86WV6_V5V | V5V | n/a | n/a | CHEMBL5095233 | (1R,3R,15E,28R,29R,30R,31R,34R,36R,39S,41R)-29,41-difluoro-34,39-disulfanyl-2,33,35,38,40,42-hexaoxa-4,6,9,11,13,18,20,22,25,27-decaaza-34,39-diphosphaoctacyclo[28.6.4.1~3,36~.1~28,31~.0~4,8~.0~7,12~.0~19,24~.0~23,27~]dotetraconta-5,7,9,11,15,19,21,23,25-nonaene 34,39-dioxide (non-preferred name) | n/a | |
| 33 | Q86WV6_V7E | V7E | n/a | 163201210 | n/a | 3',3'-c-di-araAMP | n/a | |
| 34 | Q86WV6_W78 | W78 | n/a | n/a | CHEMBL5437294 | 3-[(1~{R},3~{R},6~{R},8~{R},9~{R},10~{R},12~{R},15~{R},17~{R},18~{R})-8-(6-aminopurin-9-yl)-9-fluoranyl-18-oxidanyl-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-6~{H}-imidazo[4,5-d]pyridazin-7-one | n/a | |
| 35 | Q86WV6_WWU | WWU | n/a | 153624047 | CHEMBL5404655 | 1-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-methoxy-1H-benzimidazole-5-carboxamide | n/a | |
| 36 | Q86WV6_WX8 | WX8 | n/a | 155787013 | CHEMBL5399999 | 3-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-3H-imidazo[4,5-b]pyridine-6-carboxamide | n/a | |
| 37 | Q86WV6_YGI | YGI | n/a | 1468371 | n/a | {[(4S)-8,9-dimethylthieno[3,2-e][1,2,4]triazolo[4,3-c]pyrimidin-3-yl]sulfanyl}acetic acid | n/a | |
| 38 | Q86WV6_ZEV | ZEV | n/a | n/a | n/a | (2R,5R,7R,8S,10R,12aR,14R,15S,15aR,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-15,16-difluoro-2,10-bis(sulfanyl)octahydro-2H,10H,12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione | n/a | |
| 39 | Q86WV6_ZNT | ZNT | n/a | 168355704 | n/a | 2'3'-cUA | n/a |