Gene name: SIRT2
Protein name: NAD-dependent protein deacetylase
List of molecules and drugs that interact with protein Q8IXJ6
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q8IXJ6_3LX | 3LX | n/a | 21430713 | n/a | tridecanethial | n/a | |
| 2 | Q8IXJ6_3TE | 3TE | n/a | 1096292 | CHEMBL3770903 | 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]acetamide | n/a | |
| 3 | Q8IXJ6_3TK | 3TK | n/a | 1096276 | CHEMBL3769988 | N-(5-benzyl-1,3-thiazol-2-yl)-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamide | n/a | |
| 4 | Q8IXJ6_3Y0 | 3Y0 | n/a | 137348191 | n/a | [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4R,5R)-3-oxidanyl-5-sulfanyl-4-tridecoxy-oxolan-2-yl]methyl hydrogen phosphate | n/a | |
| 5 | Q8IXJ6_4I5 | 4I5 | n/a | 914268 | CHEMBL198609 | (6S)-2-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide | n/a | |
| 6 | Q8IXJ6_5GN | 5GN | n/a | 105539861 | CHEMBL3771286 | N-{5-[(7-bromonaphthalen-1-yl)methyl]-1,3-thiazol-2-yl}-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamide | n/a | |
| 7 | Q8IXJ6_5GR | 5GR | n/a | 112499922 | CHEMBL4228286 | N-(5-{3-[(1-benzyl-1H-1,2,3-triazol-4-yl)methoxy]benzyl}-1,3-thiazol-2-yl)-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamide | n/a | |
| 8 | Q8IXJ6_7KE | 7KE | n/a | 79200268 | CHEMBL4062236 | 3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]propan-1-ol | n/a | |
| 9 | Q8IXJ6_7KJ | 7KJ | n/a | 124081192 | n/a | (7~{R})-7-[(3,5-dimethyl-1,2-oxazol-4-yl)methylamino]-3-[(4-methoxynaphthalen-1-yl)methyl]-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one | n/a | |
| 10 | Q8IXJ6_8K9 | 8K9 | n/a | 6348477 | n/a | (1~{R},9~{S})-11-[(2~{R})-3-[2,4-bis(2-methylbutan-2-yl)phenoxy]-2-oxidanyl-propyl]-7,11-diazatricyclo[7.3.1.0^{2,7}]trideca-2,4-dien-6-one | n/a | |
| 11 | Q8IXJ6_8NO | 8NO | n/a | 56935695 | CHEMBL2152613 | 2-[[3-(2-phenylethoxy)phenyl]amino]benzamide | n/a | |
| 12 | Q8IXJ6_A2I | A2I | n/a | 134433608 | CHEMBL4079934 | 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[3-(phenoxymethyl)phenyl]ethanamide | n/a | |
| 13 | Q8IXJ6_A2X | A2X | n/a | 134433738 | CHEMBL4476189 | 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-(4-phenylsulfanylphenyl)ethanamide | n/a | |
| 14 | Q8IXJ6_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 15 | Q8IXJ6_AR6 | AR6 | DB02059 | 447048 | n/a | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | n/a | |
| 16 | Q8IXJ6_BME | BME | DB03345 | 1567 | CHEMBL254951 | BETA-MERCAPTOETHANOL | n/a | |
| 17 | Q8IXJ6_BTB | BTB | n/a | 81462 | n/a | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 18 | Q8IXJ6_BU3 | BU3 | n/a | 225936 | n/a | (R,R)-2,3-BUTANEDIOL | n/a | |
| 19 | Q8IXJ6_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 20 | Q8IXJ6_CNA | CNA | DB02498 | 163884 | CHEMBL5220997 | CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE | n/a | |
| 21 | Q8IXJ6_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 22 | Q8IXJ6_E7K | E7K | n/a | 138571253 | n/a | 7-(2,4-dimethyl-1H-imidazol-1-yl)-2-(5-{[4-(1H-pyrazol-1-yl)phenyl]methyl}-1,3-thiazol-2-yl)-1,2,3,4-tetrahydroisoquinoline | n/a | |
| 23 | Q8IXJ6_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 24 | Q8IXJ6_EOH | EOH | DB00898 | 702 | CHEMBL545 | ETHANOL | n/a | |
| 25 | Q8IXJ6_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 26 | Q8IXJ6_F4R | F4R | n/a | 88723176 | n/a | N-dodecylmethanethioamide | n/a | |
| 27 | Q8IXJ6_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 28 | Q8IXJ6_KXG | KXG | n/a | 145829186 | n/a | [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-sulfanyl-oxolan-2-yl]methyl hydrogen phosphate | n/a | |
| 29 | Q8IXJ6_KXJ | KXJ | n/a | 145946052 | n/a | N~2~-[3-(2-hydroxyethoxy)propanoyl]-N-phenyl-N~6~-tetradecanethioyl-L-lysinamide | n/a | |
| 30 | Q8IXJ6_KZU | KZU | n/a | 135397680 | CHEMBL4227437 | 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[5-[[3-[[1-(2-methoxyethyl)-1,2,3-triazol-4-yl]methoxy]phenyl]methyl]-1,3-thiazol-2-yl]ethanamide | n/a | |
| 31 | Q8IXJ6_L55 | L55 | n/a | 134820906 | CHEMBL4159477 | N-[3-[[3-[2-(4,6-dimethylpyrimidin-2-yl)sulfanylethanoylamino]phenyl]methoxy]phenyl]-1-methyl-pyrazole-4-carboxamide | n/a | |
| 32 | Q8IXJ6_L5C | L5C | n/a | 134820907 | CHEMBL4170094 | N-[4-[[3-[2-(4,6-dimethylpyrimidin-2-yl)sulfanylethanoylamino]phenyl]methoxy]phenyl]-1-methyl-pyrazole-4-carboxamide | n/a | |
| 33 | Q8IXJ6_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 34 | Q8IXJ6_MYR | MYR | DB08231 | 11005 | CHEMBL111077 | MYRISTIC ACID | n/a | |
| 35 | Q8IXJ6_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 36 | Q8IXJ6_NAD | NAD | DB14128 | 5892;5288979;10897651;73415790; | CHEMBL1234613 | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | n/a | |
| 37 | Q8IXJ6_NCA | NCA | DB02701 | 936 | CHEMBL1140 | NICOTINAMIDE | n/a | IC50(nM) = 1200.0 |
| 38 | Q8IXJ6_OCZ | OCZ | n/a | 707029 | CHEMBL597477 | (1S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1- carboxamide | n/a | |
| 39 | Q8IXJ6_OMR | OMR | n/a | 102596388 | n/a | [(2S,3R,4R,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-2,4-bis(oxidanyl)oxolan-3-yl] tetradecanoate | n/a | |
| 40 | Q8IXJ6_P6G | P6G | n/a | 17472 | CHEMBL1235082 | HEXAETHYLENE GLYCOL | n/a | |
| 41 | Q8IXJ6_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 42 | Q8IXJ6_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 43 | Q8IXJ6_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 44 | Q8IXJ6_QUE | QUE | DB04216 | 5280343 | CHEMBL50 | 3,5,7,3',4'-PENTAHYDROXYFLAVONE | n/a | |
| 45 | Q8IXJ6_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 46 | Q8IXJ6_YDD | YDD | n/a | 155818901 | n/a | [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4R,5S)-3,4-bis(oxidanyl)-5-tetradecoxy-oxolan-2-yl]methyl hydrogen phosphate | n/a | |
| 47 | Q8IXJ6_YOY | YOY | n/a | 155818927 | n/a | [[(2S,3aS,5S,6R,6aS)-2-dodecyl-6-oxidanyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | n/a | |
| 48 | Q8IXJ6_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 49 | Q8IXJ6_DB15493 | n/a | DB15493 | n/a | n/a | Cambinol | inhibitor |