Gene name: SIRT6
Protein name: NAD-dependent protein deacylase
List of molecules and drugs that interact with protein Q8N6T7
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q8N6T7_08D | 08D | DB01015 | 5329 | CHEMBL443 | Sulfamethoxazole | n/a | |
| 2 | Q8N6T7_115 | 115 | DB01095 | 446155 | CHEMBL1078 | (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | n/a | EC50(nM) = 7100.0 |
| 3 | Q8N6T7_3AB | 3AB | n/a | 1645 | CHEMBL81977 | 3-aminobenzamide | n/a | |
| 4 | Q8N6T7_4NC | 4NC | DB03407 | 3505109 | CHEMBL42423 | 4-NITROCATECHOL | n/a | |
| 5 | Q8N6T7_6GO | 6GO | n/a | 65275 | CHEMBL226395 | 6-O-methylguanine | n/a | |
| 6 | Q8N6T7_7M2 | 7M2 | n/a | 6928968 | n/a | (4~{R})-4-pyridin-3-yl-4,5-dihydropyrrolo[1,2-a]quinoxaline | n/a | |
| 7 | Q8N6T7_7M5 | 7M5 | n/a | 60148051 | CHEMBL3823966 | 4-pyridin-3-ylpyrrolo[1,2-a]quinoxaline | n/a | |
| 8 | Q8N6T7_7M9 | 7M9 | n/a | 137348646 | n/a | 1-pyrrolo[1,2-a]quinoxalin-4-ylnaphthalen-2-ol | n/a | |
| 9 | Q8N6T7_7N2 | 7N2 | n/a | 3246618 | CHEMBL1329102 | (4~{R})-4-pyridin-3-yl-5-[3-(trifluoromethyl)phenyl]sulfonyl-4~{H}-pyrrolo[1,2-a]quinoxaline | n/a | |
| 10 | Q8N6T7_8L9 | 8L9 | n/a | 134717373 | CHEMBL4440358 | 5-[[3,5-bis(chloranyl)phenyl]sulfonylamino]-2-[(5-bromanyl-4-fluoranyl-2-methyl-phenyl)sulfamoyl]benzoic acid | n/a | |
| 11 | Q8N6T7_A2N | A2N | n/a | 23636413 | n/a | [(2R,3S,4R,5R)-4-(acetylamino)-3,5-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate | n/a | |
| 12 | Q8N6T7_APR | APR | n/a | 445794 | CHEMBL1231026 | ADENOSINE-5-DIPHOSPHORIBOSE | n/a | |
| 13 | Q8N6T7_AR6 | AR6 | DB02059 | 447048 | n/a | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | n/a | |
| 14 | Q8N6T7_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 15 | Q8N6T7_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 16 | Q8N6T7_G4U | G4U | n/a | 53956909 | n/a | tetradecanethial | n/a | |
| 17 | Q8N6T7_G4X | G4X | n/a | 53922026 | n/a | hexadecanethial | n/a | |
| 18 | Q8N6T7_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 19 | Q8N6T7_GV9 | GV9 | n/a | 2807579 | n/a | 3-(acetylamino)thiophene-2-carboxylic acid | n/a | |
| 20 | Q8N6T7_HBD | HBD | n/a | 65052 | CHEMBL123617 | 4-HYDROXYBENZAMIDE | n/a | |
| 21 | Q8N6T7_HDR | HDR | n/a | 6914363 | n/a | HEXADECANE-1-SULFINIC ACID | n/a | |
| 22 | Q8N6T7_HIC | HIC | DB04151 | 92105;7020397; | CHEMBL1233327 | 4-METHYL-HISTIDINE | n/a | |
| 23 | Q8N6T7_HW2 | HW2 | DB12665 | 5280804 | CHEMBL250450 | isoquercetin | n/a | |
| 24 | Q8N6T7_HWB | HWB | n/a | 128861 | CHEMBL404515 | cyanidin | n/a | |
| 25 | Q8N6T7_I7B | I7B | n/a | 67136 | CHEMBL266240 | 4-AMINO-6-CHLOROBENZENE-1,3-DISULFONAMIDE | n/a | |
| 26 | Q8N6T7_ISN | ISN | DB02095 | 7054 | CHEMBL326294 | ISATIN | n/a | |
| 27 | Q8N6T7_NCA | NCA | DB02701 | 936 | CHEMBL1140 | NICOTINAMIDE | n/a | IC50(nM) = 45000.0 |
| 28 | Q8N6T7_P6G | P6G | n/a | 17472 | CHEMBL1235082 | HEXAETHYLENE GLYCOL | n/a | |
| 29 | Q8N6T7_PCA | PCA | DB03088 | 7405 | CHEMBL397976 | PYROGLUTAMIC ACID | n/a | |
| 30 | Q8N6T7_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 31 | Q8N6T7_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 32 | Q8N6T7_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 33 | Q8N6T7_QTI | QTI | n/a | 37302853 | n/a | 3-[4-[[5-(2-fluorophenyl)thiophen-2-yl]methyl]piperazin-1-yl]sulfonylbenzenesulfonamide | n/a | |
| 34 | Q8N6T7_QUE | QUE | DB04216 | 5280343 | CHEMBL50 | 3,5,7,3',4'-PENTAHYDROXYFLAVONE | n/a | IC50(nM) = 1900.0 EC50(nM) = 990000.0 |
| 35 | Q8N6T7_QY3 | QY3 | n/a | 139016541 | n/a | 2-azanyl-5-[4-[[5-(2-fluorophenyl)thiophen-2-yl]methyl]piperazin-1-yl]sulfonyl-benzenesulfonamide | n/a | |
| 36 | Q8N6T7_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 37 | Q8N6T7_TBU | TBU | DB03900 | 6386 | CHEMBL16502 | TERTIARY-BUTYL ALCOHOL | n/a | |
| 38 | Q8N6T7_TSN | TSN | DB04297 | 444732 | CHEMBL99 | TRICHOSTATIN A | n/a | Ki(nM) = 2000.0 Kd(nM) = 29000.0 |
| 39 | Q8N6T7_UNX | UNX | n/a | |||||
| 40 | Q8N6T7_XEG | XEG | DB16120 | 5276454 | CHEMBL483083 | (2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate | n/a | |
| 41 | Q8N6T7_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 42 | Q8N6T7_ZSL | ZSL | n/a | 167713226 | n/a | [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(3aR,5R,6R,6aR)-6-hydroxytetrahydro-2H-furo[2,3-d][1,3]oxathiol-5-yl]methyl dihydrogen diphosphate (non-preferred name) | n/a | |
| 43 | Q8N6T7_STL | STL | DB02709 | 445154 | CHEMBL165 | RESVERATROL | n/a |