Gene name: CGAS
Protein name: Cyclic GMP-AMP synthase
List of molecules and drugs that interact with protein Q8N884
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q8N884_1SY | 1SY | n/a | 71563406;135564529; | CHEMBL4465054 | cGAMP | n/a | |
| 2 | Q8N884_1YC | 1YC | n/a | 71656176;135566854; | CHEMBL4435159 | 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one | n/a | |
| 3 | Q8N884_4BW | 4BW | n/a | 11181459;135471108; | CHEMBL4449584 | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one | n/a | |
| 4 | Q8N884_8ZM | 8ZM | n/a | n/a | CHEMBL4065757 | 5-phenyltetrazolo[1,5-a]pyrimidin-7-ol | n/a | |
| 5 | Q8N884_9B7 | 9B7 | n/a | 46937432;135567332; | CHEMBL4803833 | 3',3'-cdIMP | n/a | |
| 6 | Q8N884_9BG | 9BG | n/a | 131633034;135567331; | n/a | 2',5'-GpAp | n/a | |
| 7 | Q8N884_9BJ | 9BJ | n/a | 137348799 | n/a | 3',3'-cdUMP | n/a | |
| 8 | Q8N884_9BS | 9BS | n/a | 10313237 | n/a | 2-(pyridin-2-yl)pyrimidine | n/a | |
| 9 | Q8N884_9BV | 9BV | n/a | n/a | n/a | tetrazolo[5,1-b]quinazolin-9-ol | n/a | |
| 10 | Q8N884_9BY | 9BY | n/a | 2545757;3000086; | CHEMBL1403557 | [2-(1,3-thiazol-4-yl)-1H-benzimidazol-1-yl]acetic acid | n/a | |
| 11 | Q8N884_AEV | AEV | n/a | 131704467 | n/a | 2-(4,5-dichloro-1H-benzimidazol-2-yl)-5-methyl-4-[(1R)-3-oxo-1,3-dihydro-2-benzofuran-1-yl]-1,2-dihydro-3H-pyrazol-3-one | n/a | |
| 12 | Q8N884_ATP | ATP | DB00171 | 5957 | CHEMBL14249 | ADENOSINE-5'-TRIPHOSPHATE | n/a | |
| 13 | Q8N884_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | n/a | |
| 14 | Q8N884_EQL | EQL | n/a | 3531088 | n/a | 1,3-bis(oxidanylidene)benzo[de]isoquinoline-6,7-dicarboxylic acid | n/a | |
| 15 | Q8N884_EQR | EQR | n/a | 671866 | CHEMBL1410938 | 3-[5-(2-hydroxy-2-oxoethyl)-3-oxidanylidene-[1,2,4]triazino[2,3-a]benzimidazol-2-yl]propanoic acid | n/a | |
| 16 | Q8N884_EQX | EQX | n/a | 4445910 | CHEMBL1397063 | 4-[2-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazinyl]-4-oxidanylidene-butanoic acid | n/a | |
| 17 | Q8N884_ER6 | ER6 | n/a | 92308306 | n/a | (3R)-1-pyrrolo[1,2-a]quinoxalin-4-ylpiperidine-3-carboxylic acid | n/a | |
| 18 | Q8N884_ER9 | ER9 | n/a | 5304665 | CHEMBL5173649 | 3-[[5-(1,2,4-triazol-4-yl)-4H-1,2,4-triazol-3-yl]carbonylamino]benzoic acid | n/a | |
| 19 | Q8N884_JUJ | JUJ | n/a | 138393372 | CHEMBL4448176 | 1-[9-(6-aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethan-1-one | n/a | |
| 20 | Q8N884_JUM | JUM | n/a | 138393371 | CHEMBL5081956 | 1-[6,7-dichloro-9-(1H-pyrazol-4-yl)-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethan-1-one | n/a | |
| 21 | Q8N884_KHM | KHM | n/a | n/a | CHEMBL4096573 | (1R,2S)-2-[(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]cyclohexane-1-carboxylic acid | n/a | |
| 22 | Q8N884_KKM | KKM | n/a | n/a | CHEMBL4084664 | 7-hydroxy-N-[(2S)-1-hydroxypropan-2-yl]-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide | n/a | |
| 23 | Q8N884_KKP | KKP | n/a | n/a | CHEMBL4085628 | 7-hydroxy-N-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide | n/a | |
| 24 | Q8N884_LLS | LLS | n/a | n/a | n/a | (3~{S})-3-[1-[4,5-bis(chloranyl)-1~{H}-benzimidazol-2-yl]-3-methyl-5-oxidanyl-pyrazol-4-yl]-3~{H}-2-benzofuran-1-one | n/a | |
| 25 | Q8N884_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 26 | Q8N884_PTD | PTD | DB03266 | 3485 | CHEMBL1235482 | PENTANEDIAL | n/a | |
| 27 | Q8N884_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 28 | Q8N884_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a |