Gene name: PDEB1
Protein name: Phosphodiesterase (EC 3.1.4.-)
List of molecules and drugs that interact with protein Q8WQX9
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q8WQX9_6M5 | 6M5 | n/a | 71719394 | CHEMBL2326941 | (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-methoxy-3-[4-[4-(1~{H}-1,2,3,4-tetrazol-5-yl)phenoxy]butoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | n/a | |
| 2 | Q8WQX9_863 | 863 | n/a | 145945967 | n/a | 5-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-isopropyl-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one | n/a | |
| 3 | Q8WQX9_8Z4 | 8Z4 | n/a | 132471725 | CHEMBL4208363 | (4AS,8AR)-4-(3-{4-[(3R)-3-HYDROXYPYRROLIDINE-1- | n/a | |
| 4 | Q8WQX9_908 | 908 | n/a | 132471729 | CHEMBL4204999 | 4-[5-[(4~{a}~{R},8~{a}~{S})-4-oxidanylidene-3-propan-2-yl-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-yl]-2-methoxy-phenyl]-~{N}-(2-azanyl-2-oxidanylidene-ethyl)benzamide | n/a | |
| 5 | Q8WQX9_CVA | CVA | n/a | 137349131 | CHEMBL4204966 | 2-[(4-{5-[(4aR,8aS)-3-cycloheptyl-4-oxo-3,4,4a,5,8,8a-hexahydrophthalazin-1-yl]-2-methoxyphenyl}phenyl)formamido]-N-(2-hydroxyethyl)acetamide | n/a | |
| 6 | Q8WQX9_CVL | CVL | n/a | 71460705 | CHEMBL2171456 | 5-[4-methoxy-3-[4-[4-(1~{H}-1,2,3,4-tetrazol-5-yl)phenoxy]butoxy]phenyl]-4,4-dimethyl-2-propan-2-yl-pyrazol-3-one | n/a | |
| 7 | Q8WQX9_D5T | D5T | n/a | 137700766 | CHEMBL4441748 | 1-[2-[4-[(4~{a}~{S},8~{a}~{R})-4-(3,4-dimethoxyphenyl)-1-oxidanylidene-4~{a},5,8,8~{a}-tetrahydrophthalazin-2-yl]piperi din-1-yl]-2-oxidanylidene-ethyl]-4,4-dimethyl-piperidine-2,6-dione | n/a | |
| 8 | Q8WQX9_D5Z | D5Z | n/a | 137700768 | CHEMBL4524402 | (4aS,8aR)-2-[1-(2-aminoquinazolin-4-yl)piperidin-4-yl]-4-(3,4-dimethoxyphenyl)-1,2,4a,5,8,8a-hexahydrophthalazin-1-one | n/a | |
| 9 | Q8WQX9_D62 | D62 | n/a | 137700767 | CHEMBL4460623 | (4aS,8aR)-2-(1-{2-aminothieno[2,3-d]pyrimidin-4-yl}piperidin-4-yl)-4-(3,4- dimethoxyphenyl)-1,2,4a,5,8,8a-hexahydrophthalazin-1-one | n/a | |
| 10 | Q8WQX9_D68 | D68 | n/a | 137700769 | CHEMBL4530777 | 1-(2-{4-[(4aS,8aR)-4-[3,4-bis(difluoromethoxy)phenyl]-1-oxo-1,2,4a,5,8,8a-hexahydrophthalazin-2-yl]piperidin-1-yl}-2-oxoethyl)-4,4-dimethylpiperidine-2,6-dione | n/a | |
| 11 | Q8WQX9_E3Q | E3Q | n/a | 138753174 | n/a | 1-cycloheptyl-3-{4-methoxy-3-[(2-methoxyphenyl)methoxy]phenyl}-4,4-dimethyl-4,5-dihydro- 1H-pyrazol-5-one | n/a | |
| 12 | Q8WQX9_E6Z | E6Z | n/a | 138753179 | CHEMBL4465919 | 3-{5-[(4aR,8aS)-3-cycloheptyl-4-oxo-3,4,4a,5,8,8a-hexahydrophthalazin-1-yl]-2-methoxyphenyl}prop-2-ynamide | n/a | |
| 13 | Q8WQX9_E8H | E8H | n/a | 9827600 | CHEMBL4566742 | 1-(2-{4-[(4aS,8aR)-4-(3,4-dimethoxyphenyl)-1-oxo-1,2,4a,5,8,8a-hexahydrophthalazin-2-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione | n/a | |
| 14 | Q8WQX9_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 15 | Q8WQX9_EOH | EOH | DB00898 | 702 | CHEMBL545 | ETHANOL | n/a | |
| 16 | Q8WQX9_FFZ | FFZ | n/a | 138454907 | CHEMBL4436770 | 3-[5-[(4aR,8aS)-4-OXIDANYLIDENE-3-PROPAN-2-YL-4a,5,8,8a-TETRAHYDROPHTHALAZIN-1-YL]-2-METHOXY-PHENYL]-N-(PHENYLMETHYL)PROP-2-YNAMIDE | n/a | |
| 17 | Q8WQX9_FMT | FMT | DB01942 | 284;18971002; | CHEMBL116736 | FORMIC ACID | n/a | |
| 18 | Q8WQX9_GAI | GAI | DB00536 | 3520 | CHEMBL821 | GUANIDINE | n/a | |
| 19 | Q8WQX9_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 20 | Q8WQX9_J2E | J2E | n/a | 71460717 | CHEMBL2171660 | 1-cycloheptyl-3-[3-(cyclopentyloxy)-4-methoxyphenyl]-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one | n/a | |
| 21 | Q8WQX9_JX2 | JX2 | n/a | 138857410 | CHEMBL4464777 | 3-[5-[(4~{a}~{R},8~{a}~{S})-3-cycloheptyl-4-oxidanylidene-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-yl]-2-methoxy-phenyl]-~{N}-(furan-2-ylmethyl)prop-2-ynamide | n/a | |
| 22 | Q8WQX9_K1Q | K1Q | n/a | 138753641 | CHEMBL4443772 | 3-[5-[(4~{a}~{R},8~{a}~{S})-4-oxidanylidene-3-propan-2-yl-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-yl]-2-methoxy-phenyl]-~{N}-[2-(2-fluorophenyl)ethyl]prop-2-ynamide | n/a | |
| 23 | Q8WQX9_K3N | K3N | n/a | 138857411 | n/a | 3-[5-[(4~{a}~{R},8~{a}~{S})-3-cycloheptyl-4-oxidanylidene-4~{a},5,6,7,8,8~{a}-hexahydrophthalazin-1-yl]-2-methoxy-phenyl]-~{N}-butyl-prop-2-ynamide | n/a | |
| 24 | Q8WQX9_K3W | K3W | n/a | 138753640 | CHEMBL4453045 | 3-[5-[(4~{a}~{R},8~{a}~{S})-4-oxidanylidene-3-propan-2-yl-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-yl]-2-methoxy-phenyl]-~{N}-(3-methoxyphenyl)prop-2-ynamide | n/a | |
| 25 | Q8WQX9_LQY | LQY | n/a | 137349704 | CHEMBL4210475 | N-(2-amino-2-oxoethyl)-5'-[(4aR,8aS)-3-cycloheptyl-4-oxo-3,4,4a,5,8,8a-hexahydrophthalazin-1-yl]-2'-methoxy[1,1'-biphenyl]-4-carboxamide | n/a | |
| 26 | Q8WQX9_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 27 | Q8WQX9_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 28 | Q8WQX9_PIL | PIL | DB01791 | 154575 | CHEMBL42126 | 3-(CYCLOPENTYLOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-METHOXYBENZAMIDE | n/a | |
| 29 | Q8WQX9_QWT | QWT | n/a | 71460703 | CHEMBL2171452 | 1-cycloheptyl-3-(4-methoxy-3-{4-[4-(1H-1,2,3,4-tetrazol-5-yl)phenoxy]butoxy}phenyl)-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one | n/a | |
| 30 | Q8WQX9_QWZ | QWZ | n/a | 71449884 | CHEMBL2171459 | 1-cycloheptyl-3-{4-methoxy-3-[2-(4-methoxyphenyl)ethoxy]phenyl}-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one | n/a | |
| 31 | Q8WQX9_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a |