Gene name: PKMYT1
Protein name: Membrane-associated tyrosine- and
List of molecules and drugs that interact with protein Q99640
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q99640_1N1 | 1N1 | DB01254 | 3062316 | CHEMBL1421 | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE | n/a | Ki(nM) = 0.5 IC50(nM) = 6.0 Kd(nM) = 130.0 |
| 2 | Q99640_8X7 | 8X7 | DB11740 | 24856436 | CHEMBL1976040 | 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one | n/a | |
| 3 | Q99640_93J | 93J | DB05524 | 6445562 | CHEMBL607707 | (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(dimethylamino)but-2-enamide | n/a | |
| 4 | Q99640_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 5 | Q99640_DB8 | DB8 | DB06616 | 5328940 | CHEMBL288441 | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | n/a | Ki(nM) = 13.0 IC50(nM) = 133.0 Kd(nM) = 270.0 |
| 6 | Q99640_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 7 | Q99640_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 8 | Q99640_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 9 | Q99640_H8H | H8H | DB11805 | 10302451 | CHEMBL217092 | N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE | n/a | |
| 10 | Q99640_P48 | P48 | DB16232 | 16718576 | CHEMBL564829 | N,1,4,4-TETRAMETHYL-8-{[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]AMINO}-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE | n/a | |
| 11 | Q99640_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 12 | Q99640_QG5 | QG5 | n/a | 91933866 | CHEMBL3321809 | (1M)-2-amino-1-(5-hydroxy-2-methylphenyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide | n/a | |
| 13 | Q99640_QGI | QGI | DB19241 | 156869388 | CHEMBL5199076 | (1P)-2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide | n/a | |
| 14 | Q99640_QGR | QGR | n/a | 164575522 | CHEMBL5185146 | (1P)-2-amino-6-bromo-1-(3-hydroxy-2,6-dimethylphenyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide | n/a | |
| 15 | Q99640_QGY | QGY | n/a | 164575523 | CHEMBL5181222 | (1P)-2-amino-5-bromo-1-(3-hydroxy-2,6-dimethylphenyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide | n/a | |
| 16 | Q99640_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 17 | Q99640_W9X | W9X | n/a | 169410465 | n/a | [6-azanyl-5-(2,6-dimethyl-3-oxidanyl-phenyl)-2,3-dimethyl-pyrrolo[2,3-b]pyrazin-7-yl]-(6,7-dihydro-4~{H}-pyrazolo[1,5-a]pyrazin-5-yl)methanone | n/a | |
| 18 | Q99640_XZN | XZN | n/a | 60202320 | CHEMBL4067978 | 4-[(3,5-DICHLORO-4-METHOXYPHENYL)AMINO]-6-METHOXY-7-[3-(4-METHYLPIPERAZIN-1-YL)PROPOXY]QUINOLINE-3-CARBONITRILE | n/a | |
| 19 | Q99640_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |