Gene name: MAP3K5
Protein name: Mitogen-activated protein kinase
List of molecules and drugs that interact with protein Q99683
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q99683_8GS | 8GS | n/a | 127053602 | CHEMBL3952214 | 2-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}-2,3-dihydro-1H-isoindol-1-one | n/a | |
| 2 | Q99683_8GV | 8GV | n/a | 127053598 | CHEMBL3946139 | 6-{[(2S)-4-methylmorpholin-2-yl]methoxy}-2-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}-2,3-dihydro-1H-isoindol-1-one | n/a | |
| 3 | Q99683_8GY | 8GY | n/a | 127053601 | CHEMBL3954836 | 2-(6-{4-[(2R)-1-hydroxypropan-2-yl]-4H-1,2,4-triazol-3-yl}pyridin-2-yl)-6-[(propan-2-yl)oxy]-2,3-dihydro-1H-isoindol-1-one | n/a | |
| 4 | Q99683_8V4 | 8V4 | n/a | 53508010 | n/a | N-(1-ethyl-1H-pyrazol-4-yl)furan-3-carboxamide | n/a | |
| 5 | Q99683_8V7 | 8V7 | n/a | 124222752 | CHEMBL4105386 | 2-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]-N-(pyridin-2-yl)-1,3-thiazole-4-carboxamide | n/a | |
| 6 | Q99683_9E1 | 9E1 | n/a | 131955124 | CHEMBL4278211 | 2-methoxy-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}-5-sulfamoylbenzamide | n/a | |
| 7 | Q99683_9E4 | 9E4 | n/a | 131955125 | CHEMBL4279174 | 4-methoxy-N~1~-methyl-N~3~-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}benzene-1,3-dicarboxamide | n/a | |
| 8 | Q99683_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 9 | Q99683_BH9 | BH9 | n/a | 24945008 | CHEMBL3330167 | 4-tert-butyl-N-[6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-2-yl]benzamide | n/a | |
| 10 | Q99683_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 11 | Q99683_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 12 | Q99683_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 13 | Q99683_IE4 | IE4 | n/a | 71581422 | CHEMBL3330169 | N-(2-aminoethyl)-5-{1H-pyrrolo[2,3-b]pyridin-3-yl}thiophene-2-sulfonamide | n/a | |
| 14 | Q99683_IE6 | IE6 | n/a | 25118862 | CHEMBL3330172 | N-(2-aminoethyl)-5-{2-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl}thiophene-2-sulfonamide | n/a | |
| 15 | Q99683_IE8 | IE8 | n/a | 71581423 | CHEMBL3330168 | 5-[(1R)-2-amino-1-phenylethoxy]-2-(furan-3-yl)-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}pyridine | n/a | |
| 16 | Q99683_IEO | IEO | n/a | 71581421 | CHEMBL3330171 | 3-cyano-4-(piperidin-4-yloxy)-1H-indole-7-carboxamide | n/a | |
| 17 | Q99683_IM6 | IM6 | n/a | 24944925 | CHEMBL1642655 | 4-tert-butyl-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide | n/a | |
| 18 | Q99683_KK7 | KK7 | n/a | 38314118 | n/a | N-[3-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamide | n/a | |
| 19 | Q99683_KK8 | KK8 | n/a | 58102999 | n/a | N-[3-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)phenyl][3,4'-bipyridine]-2'-carboxamide | n/a | |
| 20 | Q99683_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 21 | Q99683_NJV | NJV | DB14916 | 71245288 | CHEMBL3916717 | 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}benzamide | inhibitor | |
| 22 | Q99683_NKJ | NKJ | n/a | 140430627 | CHEMBL4514925 | (19S)-19-methyl-16,17,18,19-tetrahydro-8,4-(azeno)[1,2,4]triazolo[4,3-f][1,6,13]benzoxadiazacyclohexadecin-10(9H)-one | n/a | |
| 23 | Q99683_RFG | RFG | n/a | 146027049 | CHEMBL4632672 | 3-methoxy-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}-1-(pyrazin-2-yl)-1H-pyrazole-4-carboxamide | n/a | |
| 24 | Q99683_S0L | S0L | n/a | 57504987 | CHEMBL4783726 | 4-(4-cyclopropyl-1H-imidazol-1-yl)-N-[3-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamide | n/a | |
| 25 | Q99683_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 26 | Q99683_V3S | V3S | n/a | 153835404 | n/a | (2R)-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}oxane-2-carboxamide | n/a | |
| 27 | Q99683_STU | STU | DB02010 | 44259 | CHEMBL388978 | STAUROSPORINE | n/a |