Gene name: SIGMAR1
Protein name: Sigma non-opioid intracellular
List of molecules and drugs that interact with protein Q99720
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q99720_61V | 61V | n/a | 132995 | CHEMBL50112 | N-(1-benzylpiperidin-4-yl)-4-iodobenzamide | n/a | |
| 2 | Q99720_61W | 61W | n/a | 9817231 | CHEMBL4088272 | 3-(4-methylphenyl)-5-(1-propyl-3,6-dihydro-2H-pyridin-5-yl)-1,2-oxazole | n/a | |
| 3 | Q99720_GKY | GKY | n/a | 9841596 | CHEMBL190883 | N-{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl}-N-propylpropan-1-amine | n/a | |
| 4 | Q99720_GM4 | GM4 | n/a | 12259685 | CHEMBL60542 | (2S,6S,11S)-6,11-dimethyl-3-(3-methylbut-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol | n/a | |
| 5 | Q99720_GMJ | GMJ | DB00502 | 3559 | CHEMBL54 | 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one | n/a | Ki(nM) = 0.2 IC50(nM) = 2.1 |
| 6 | Q99720_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 7 | Q99720_OLC | OLC | n/a | 11451146 | n/a | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | n/a | |
| 8 | Q99720_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 9 | Q99720_TP0 | TP0 | DB00321 | 2160 | CHEMBL629 | Amitriptyline | agonist | |
| 10 | Q99720_DB00409 | n/a | DB00409 | n/a | n/a | Remoxipride | antagonist | Ki(nM) = 55.0 |
| 11 | Q99720_DB00514 | n/a | DB00514 | n/a | n/a | Dextromethorphan | agonist | Ki(nM) = 348.0 |
| 12 | Q99720_DB00574 | n/a | DB00574 | n/a | n/a | Fenfluramine | antagonist | |
| 13 | Q99720_DB00652 | n/a | DB00652 | n/a | n/a | Pentazocine | agonist | Ki(nM) = 3.1 |
| 14 | Q99720_DB00704 | n/a | DB00704 | n/a | n/a | Naltrexone | n/a | |
| 15 | Q99720_COC | COC | DB00907 | 446220 | CHEMBL370805 | Cocaine | agonist | |
| 16 | Q99720_DB00956 | n/a | DB00956 | n/a | n/a | Hydrocodone | ligand | |
| 17 | Q99720_DB01488 | n/a | DB01488 | n/a | n/a | Dimethyltryptamine | inhibitor | Ki(nM) = 5209.0 |
| 18 | Q99720_AND | AND | DB01708 | 5881 | CHEMBL90593 | Prasterone | agonist | |
| 19 | Q99720_1PC | 1PC | DB03575 | 6468 | CHEMBL275528 | Phencyclidine | n/a | Ki(nM) = 1090.0 IC50(nM) = 560.0 |
| 20 | Q99720_DB05316 | n/a | DB05316 | n/a | n/a | Pimavanserin | binder | |
| 21 | Q99720_08N | 08N | DB06174 | 275196 | CHEMBL364713 | Noscapine | n/a | |
| 22 | Q99720_DB09014 | n/a | DB09014 | n/a | n/a | Captodiame | agonist | |
| 23 | Q99720_DB11186 | n/a | DB11186 | n/a | n/a | Pentoxyverine | agonist |