Q99835 SMO_HUMAN
Gene name: SMO
Protein name: Protein smoothened (Protein

List of molecules and drugs that interact with protein Q99835

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	Q99835_836	836	n/a	126970683	n/a	N-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-4-nitro-2-(trifluoromethyl)benzamide	n/a
2	Q99835_A8T	A8T	n/a	24905375	CHEMBL485870	2-{6-[4-(4-benzylphthalazin-1-yl)piperazin-1-yl]pyridin-3-yl}propan-2-ol	n/a
3	Q99835_CLR	CLR	DB04540	5997	CHEMBL112570	CHOLESTEROL	n/a
4	Q99835_CO1	CO1	n/a	3247059	CHEMBL434302	17-[3-(3,3-DIMETHYL-OXIRANYL)-1-METHYL-PROPYL]-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYC LOPENTA[A]PHENANTHREN-3-OL	n/a
5	Q99835_CY8	CY8	n/a	442972	CHEMBL254129	Cyclopamine	n/a
6	Q99835_FMN	FMN	DB03247	643976	CHEMBL1201794	FLAVIN MONONUCLEOTIDE	n/a
7	Q99835_MPG	MPG	DB03831	17754086	n/a	[(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate	n/a
8	Q99835_NA	NA	n/a	923	n/a	SODIUM ION	n/a
9	Q99835_NAG	NAG	DB00141	24139	CHEMBL447878	2-acetamido-2-deoxy-beta-D-glucopyranose	n/a
10	Q99835_OLC	OLC	n/a	11451146	n/a	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate	n/a
11	Q99835_SG8	SG8	n/a	n/a	n/a	3-chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[3-(pyridin-4-yl)benzyl]-1-benzothiophene-2-carboxamide	n/a
12	Q99835_V0S	V0S	n/a	n/a	CHEMBL1221983	3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-{[3-(pyridin-4-yl)phenyl]methyl}-1-benzothiophene-2-carboxamide	n/a
13	Q99835_VIS	VIS	DB08828	24776445	CHEMBL473417	2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide	antagonist	Ki(nM) = 16.2 IC50(nM) = 0.4 Kd(nM) = 97.5 EC50(nM) = 2.0
14	Q99835_ZN	ZN	n/a	32051	CHEMBL1236970	ZINC ION	n/a
15	Q99835_DB01047	n/a	DB01047	n/a	n/a	Fluocinonide	agonist
16	Q99835_DB06786	n/a	DB06786	n/a	n/a	Halcinonide	agonist
17	Q99835_DB09143	n/a	DB09143	n/a	n/a	Sonidegib	antagonist	Ki(nM) = 6.0
18	Q99835_DB11978	n/a	DB11978	n/a	n/a	Glasdegib	inhibitor