Gene name: KPC-2
Protein name: Carbapenem-hydrolyzing beta-lactamase KPC-2
List of molecules and drugs that interact with protein Q9F663
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9F663_1CE | 1CE | DB06889 | 6458152 | CHEMBL1213446 | 3-(1H-tetrazol-5-ylmethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one | n/a | |
| 2 | Q9F663_4D6 | 4D6 | DB12107 | 56649692 | CHEMBL3317857 | Vaborbactam | inhibitor | |
| 3 | Q9F663_7TC | 7TC | n/a | 165412405 | n/a | (2R,3S)-3-methyl-4-methylidene-2-[(2S,3R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-2,3-dihydropyrrole-5-carboxylic acid | n/a | |
| 4 | Q9F663_8YF | 8YF | n/a | 444648 | n/a | (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid | n/a | |
| 5 | Q9F663_8YL | 8YL | n/a | 10069633 | n/a | (2S,3R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfan yl-3-methyl-2,3-dihydro-1H-pyrrole-5-carboxylic acid | n/a | |
| 6 | Q9F663_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 7 | Q9F663_AIX | AIX | n/a | 11840918 | n/a | (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | n/a | |
| 8 | Q9F663_C8V | C8V | n/a | 137349066 | n/a | (2S,5R)-1-formyl-N'-[(3R)-piperidine-3-carbonyl]-5-[(sulfooxy)amino]piperidine-2-carbohydrazide | n/a | |
| 9 | Q9F663_C8Y | C8Y | n/a | 137349067 | n/a | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carbonitrile | n/a | |
| 10 | Q9F663_C9D | C9D | n/a | 137349071 | n/a | (2S,5R)-1-formyl-N'-[(3R)-pyrrolidine-3-carbonyl]-5-[(sulfooxy)amino]piperidine-2-carbohydrazide | n/a | |
| 11 | Q9F663_CAZ | CAZ | DB03530 | 9600404 | n/a | ACYLATED CEFTAZIDIME | n/a | |
| 12 | Q9F663_CD7 | CD7 | n/a | n/a | n/a | (2S,5Z)-1-formyl-5-imino-N'-[(3R)-1-(sulfooxy)pyrrolidine-3-carbonyl]piperidine-2-carbohydrazide | n/a | |
| 13 | Q9F663_CE4 | CE4 | n/a | 6323466 | n/a | (2R)-2-[(R)-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}(carboxy)methyl]-5-methylidene-5,6-dihydro -2H-1,3-thiazine-4-carboxylic acid | n/a | |
| 14 | Q9F663_CEF | CEF | DB08375 | 131704308 | n/a | CEFOTAXIME, C3' cleaved, open, bound form | n/a | |
| 15 | Q9F663_CEO | CEO | n/a | 5287907 | n/a | 5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID | n/a | |
| 16 | Q9F663_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | n/a | |
| 17 | Q9F663_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 18 | Q9F663_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 19 | Q9F663_FUJ | FUJ | n/a | 326957 | CHEMBL4460704 | [(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)methyl]phosphonic acid | n/a | |
| 20 | Q9F663_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 21 | Q9F663_GTV | GTV | n/a | 29147132 | CHEMBL4545793 | [(5,7-dimethyl-2-oxo-2H-1-benzopyran-4-yl)methyl]phosphonic acid | n/a | |
| 22 | Q9F663_HIW | HIW | n/a | 76968691 | n/a | (2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-ca rboxylic acid | n/a | |
| 23 | Q9F663_ID1 | ID1 | n/a | 137349550 | n/a | Imipenem | n/a | |
| 24 | Q9F663_IM2 | IM2 | n/a | 5288621 | n/a | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid | n/a | |
| 25 | Q9F663_J84 | J84 | n/a | 2806191 | n/a | 1-(2,4-dichlorophenyl)-4-(1H-tetrazol-5-yl)-1H-pyrazol-5-amine | n/a | |
| 26 | Q9F663_JJT | JJT | n/a | 138857408 | n/a | (2~{S})-5-azanylidene-2-(piperidin-4-ylcarbamoyl)piperidine-1-carboxylic acid | n/a | |
| 27 | Q9F663_KJK | KJK | DB16338 | n/a | CHEMBL4463697 | (3~{R})-3-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-2-oxidanyl-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid | n/a | |
| 28 | Q9F663_LW0 | LW0 | n/a | 126513271 | n/a | 3-fluoro-N-[(1R,3S)-3-(1H-tetrazol-5-yl)-2,3-dihydro-1H-inden-1-yl]benzamide | n/a | |
| 29 | Q9F663_M2I | M2I | n/a | 166642326 | n/a | [(3S)-3-(1H-tetrazol-5-yl)-2,3-dihydro-1H-indol-1-yl][3-(trifluoromethyl)phenyl]methanone | n/a | |
| 30 | Q9F663_M53 | M53 | n/a | 166642327 | n/a | tert-butyl {(3R)-3-[(1H-tetrazol-5-yl)carbamoyl]-1-[3-(trifluoromethyl)benzoyl]-2,3-dihydro-1H-indol-3-yl}carbamate | n/a | |
| 31 | Q9F663_MK7 | MK7 | n/a | 137349751 | n/a | (2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy)amino]piperidine-2-carboxamide | n/a | |
| 32 | Q9F663_N1G | N1G | n/a | 135379590 | CHEMBL5171499 | 1,5-diphenyl-N-(1H-tetrazol-5-yl)-1H-pyrazole-3-carboxamide | n/a | |
| 33 | Q9F663_N9X | N9X | n/a | 166642329 | n/a | Ertapenem | n/a | |
| 34 | Q9F663_NPB | NPB | DB02797 | 1677 | CHEMBL20945 | 3-NITROPHENYLBORONIC ACID | n/a | |
| 35 | Q9F663_NXL | NXL | n/a | 132451794 | n/a | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide | n/a | |
| 36 | Q9F663_O2F | O2F | n/a | 166642330 | n/a | (2S,3R,4R)-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-3-methyl-2-[(2S,3R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2H-pyrrole-5-carboxylic acid | n/a | |
| 37 | Q9F663_O5E | O5E | n/a | 137796764 | n/a | (2R)-2-phenyl-2-(phenylamino)-N-(1H-tetrazol-5-yl)acetamide | n/a | |
| 38 | Q9F663_OC0 | OC0 | n/a | 166001313 | n/a | [(1~{R})-1-[2-[(5-azanyl-1,3,4-thiadiazol-2-yl)sulfanyl]ethanoylamino]-2-(4-carboxy-1,2,3-triazol-1-yl)ethyl]-$l^{3}-oxidanyl-bis(oxidanyl)boron | n/a | |
| 39 | Q9F663_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 40 | Q9F663_QNA | QNA | n/a | 140830488 | n/a | (1~{a}~{R},7~{b}~{S})-5-fluoranyl-2,2-bis(oxidanyl)-1~{a},7~{b}-dihydro-1~{H}-cyclopropa[c][1,2]benzoxaborinine-4-carboxylic acid | n/a | |
| 41 | Q9F663_R0B | R0B | n/a | 155804517 | n/a | (2~{R})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-5-butyl-2,3-dihydro-1,3-thiazole-4-carboxylic acid | n/a | |
| 42 | Q9F663_RM9 | RM9 | n/a | 140830474 | CHEMBL4633785 | (1aR,7bS)-5-fluoro-2-hydroxy-1,1a,2,7b-tetrahydrocyclopropa[c][1,2]benzoxaborinine-4-carboxylic acid | n/a | |
| 43 | Q9F663_SFR | SFR | n/a | 23627205 | n/a | (2R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-5-[(2R)-oxolan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylic acid | n/a | |
| 44 | Q9F663_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 45 | Q9F663_TWB | TWB | n/a | 29148245 | CHEMBL4560587 | [(6,7-dimethyl-2-oxo-2H-1-benzopyran-4-yl)methyl]phosphonic acid | n/a | |
| 46 | Q9F663_VKE | VKE | n/a | 39377739 | CHEMBL4539856 | [(6-oxo-2H,6H-[1,3]dioxolo[4,5-g][1]benzopyran-8-yl)methyl]phosphonic acid | n/a | |
| 47 | Q9F663_YKG | YKG | n/a | 130427303 | CHEMBL4519591 | [(5-bromo-7-methyl-2-oxo-2H-1-benzopyran-4-yl)methyl]phosphonic acid | n/a | |
| 48 | Q9F663_YOZ | YOZ | n/a | 168451754 | n/a | (2S,5R)-5-amino-1-formyl-5-hydroxy-N-(piperidin-4-yl)piperidine-2-carboxamide | n/a | |
| 49 | Q9F663_ZXM | ZXM | n/a | 71519576 | CHEMBL3586553 | 1-{(2R)-2-(dihydroxyboranyl)-2-[(thiophen-2-ylacetyl)amino]ethyl}-1H-1,2,3-triazole-4-carboxylic acid | n/a | |
| 50 | Q9F663_ZXQ | ZXQ | n/a | 66747220 | CHEMBL5172356 | {(3R,7S)-2-hydroxy-3-[2-(thiophen-2-yl)acetamido]-2,3,4,7-tetrahydro-1,2-oxaborepin-7-yl}acetic acid | n/a | |
| 51 | Q9F663_ZZ7 | ZZ7 | n/a | 6914605 | CHEMBL1237008 | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | n/a | |
| 52 | Q9F663_SR3 | SR3 | n/a | n/a | n/a | (2S,3R)-4-(2-amino-2-oxoethoxy)-3-(dihydroxy-lambda~4~-sulfanyl)-3-methyl-4-oxo-2-{[(1E)-3-oxoprop-1-en-1-yl]amino}butanoic acid | n/a |