Gene name: EGLN1
Protein name: Egl nine homolog
List of molecules and drugs that interact with protein Q9GZT9
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9GZT9_014 | 014 | n/a | 44482164 | CHEMBL1229508 | 1-(5-chloro-6-fluoro-1H-benzimidazol-2-yl)-1H-pyrazole-4-carboxylic acid | n/a | |
| 2 | Q9GZT9_1QA | 1QA | n/a | 135566826 | CHEMBL3310395 | (2S)-({[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]acetyl}amino)(phenyl)ethanoic acid | n/a | |
| 3 | Q9GZT9_2JP | 2JP | n/a | 89975828 | n/a | 4-(isoquinolin-3-ylamino)-4-oxobutanoic acid | n/a | |
| 4 | Q9GZT9_42Z | 42Z | n/a | 44469097 | CHEMBL1230217 | N-[(5,6-dichloro-1H-benzimidazol-2-yl)carbonyl]glycine | n/a | |
| 5 | Q9GZT9_4HG | 4HG | DB07112 | 6914624;156777456; | CHEMBL509064 | N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE | n/a | IC50(nM) = 1400.0 |
| 6 | Q9GZT9_4JR | 4JR | n/a | 71748680 | CHEMBL2443213 | 2-(biphenyl-4-yl)-8-[(1-methyl-1H-imidazol-2-yl)methyl]-2,8-diazaspiro[4.5]decan-1-one | n/a | |
| 7 | Q9GZT9_8UY | 8UY | n/a | 122540724 | CHEMBL4083851 | 4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile | n/a | |
| 8 | Q9GZT9_A1Z | A1Z | DB12255 | 23634441;152781920; | CHEMBL3646221 | Vadadustat | inhibitor | |
| 9 | Q9GZT9_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 10 | Q9GZT9_AKG | AKG | DB08845 | 51;156274072; | CHEMBL1686 | 2-OXOGLUTARIC ACID | n/a | |
| 11 | Q9GZT9_B2E | B2E | n/a | 131700132 | n/a | (6-hydroxy-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonyl)glycine | n/a | |
| 12 | Q9GZT9_BCT | BCT | n/a | 769;22647601; | n/a | BICARBONATE ION | n/a | |
| 13 | Q9GZT9_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 14 | Q9GZT9_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 15 | Q9GZT9_FE | FE | n/a | 29936 | n/a | FE (III) ION | n/a | |
| 16 | Q9GZT9_FE2 | FE2 | n/a | 27284 | n/a | FE (II) ION | n/a | |
| 17 | Q9GZT9_FMT | FMT | DB01942 | 284;18971002; | CHEMBL116736 | FORMIC ACID | n/a | |
| 18 | Q9GZT9_FNT | FNT | n/a | n/a | n/a | (2S)-2-{[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]amino}propanoic acid | n/a | |
| 19 | Q9GZT9_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 20 | Q9GZT9_IPA | IPA | DB02325 | 3776 | CHEMBL582 | ISOPROPYL ALCOHOL | n/a | |
| 21 | Q9GZT9_J2H | J2H | n/a | 57386523 | CHEMBL2043005 | 8-[(3-methylpyridin-2-yl)methyl]-3-(4-phenylphenyl)-1-pyrimidin-2-yl-1,3,8-triazaspiro[4.5]decane-2,4-dione | n/a | |
| 22 | Q9GZT9_KU1 | KU1 | n/a | 66809865 | n/a | N-(4-oxo-1,4-dihydrocinnoline-3-carbonyl)glycine | n/a | |
| 23 | Q9GZT9_LUW | LUW | n/a | 44232169 | n/a | 4-oxidanyl-~{N}-[(4-phenoxyphenyl)methyl]-2-pyrazol-1-yl-pyrimidine-5-carboxamide | n/a | |
| 24 | Q9GZT9_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 25 | Q9GZT9_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 26 | Q9GZT9_NI | NI | n/a | 934 | n/a | NICKEL (II) ION | n/a | |
| 27 | Q9GZT9_OGA | OGA | n/a | 3080614 | CHEMBL90852 | N-OXALYLGLYCINE | n/a | |
| 28 | Q9GZT9_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 29 | Q9GZT9_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 30 | Q9GZT9_PW2 | PW2 | n/a | 71477195 | n/a | 2-[[5-(6-methoxynaphthalen-2-yl)-3-oxidanyl-pyridin-2-yl]carbonylamino]ethanoic acid | n/a | |
| 31 | Q9GZT9_PW5 | PW5 | n/a | 155289298 | n/a | 4-[(5-bromanyl-4,6-dimethyl-pyridin-2-yl)amino]-4-oxidanylidene-butanoic acid | n/a | |
| 32 | Q9GZT9_PW8 | PW8 | n/a | 155289299 | n/a | 4-[(5-bromanylisoquinolin-3-yl)amino]-4-oxidanylidene-butanoic acid | n/a | |
| 33 | Q9GZT9_QEE | QEE | n/a | n/a | n/a | ~{tert}-butyl 6-[5-oxidanyl-4-(1,2,3-triazol-1-yl)pyrazol-1-yl]pyridine-3-carboxylate | n/a | |
| 34 | Q9GZT9_QEQ | QEQ | n/a | n/a | n/a | 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(1,2,3-triazol-1-yl)pyrazol-3-ol | n/a | |
| 35 | Q9GZT9_QNM | QNM | n/a | 16038403 | n/a | 2-[(1-methyl-2-oxidanyl-4-oxidanylidene-quinolin-3-yl)carbonylamino]ethanoic acid | n/a | |
| 36 | Q9GZT9_R8J | R8J | n/a | 59603606 | n/a | 6-(5-oxo-4-(1H-1,2,3-triazol-1-yl)-2,5-dihydro-1H-pyrazol-1-yl)nicotinic acid | n/a | |
| 37 | Q9GZT9_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 38 | Q9GZT9_UN9 | UN9 | DB08687 | 6914666 | CHEMBL426560 | N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE | n/a | IC50(nM) = 70.0 Kd(nM) = 80.0 EC50(nM) = 79000.0 |
| 39 | Q9GZT9_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 40 | Q9GZT9_ASC | ASC | DB00126 | 54670067 | CHEMBL196 | Ascorbic acid | cofactor | |
| 41 | Q9GZT9_DB01592 | n/a | DB01592 | n/a | n/a | Iron | n/a | |
| 42 | Q9GZT9_8HO | 8HO | DB04847 | 11256664 | CHEMBL2338329 | Roxadustat | inhibitor | |
| 43 | Q9GZT9_DB11682 | n/a | DB11682 | n/a | n/a | Daprodustat | inhibitor | |
| 44 | Q9GZT9_DB14488 | n/a | DB14488 | n/a | n/a | Ferrous gluconate | n/a | |
| 45 | Q9GZT9_DB14489 | n/a | DB14489 | n/a | n/a | Ferrous succinate | n/a | |
| 46 | Q9GZT9_DB14490 | n/a | DB14490 | n/a | n/a | Ferrous ascorbate | n/a | |
| 47 | Q9GZT9_DB14491 | n/a | DB14491 | n/a | n/a | Ferrous fumarate | n/a | |
| 48 | Q9GZT9_DB14501 | n/a | DB14501 | n/a | n/a | Ferrous glycine sulfate | n/a |