Gene name: P2RY12
Protein name: P2Y purinoceptor 12
List of molecules and drugs that interact with protein Q9H244
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9H244_6AD | 6AD | n/a | 121990 | CHEMBL435402 | 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate) | n/a | |
| 2 | Q9H244_6AT | 6AT | n/a | 5310983 | CHEMBL336208 | 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate) | n/a | |
| 3 | Q9H244_7Y5 | 7Y5 | DB15163 | 59534142 | CHEMBL4297589 | Selatogrel | antagonist | |
| 4 | Q9H244_AZJ | AZJ | n/a | 23649325 | CHEMBL2419490 | ethyl 6-{4-[(benzylsulfonyl)carbamoyl]piperidin-1-yl}-5-cyano-2-methylpyridine-3-carboxylate | n/a | |
| 5 | Q9H244_CLR | CLR | DB04540 | 5997 | CHEMBL112570 | CHOLESTEROL | n/a | |
| 6 | Q9H244_OLC | OLC | n/a | 11451146 | n/a | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | n/a | |
| 7 | Q9H244_TIC | TIC | DB00208 | 5472 | CHEMBL833 | Ticlopidine | antagonist | |
| 8 | Q9H244_DB00374 | n/a | DB00374 | n/a | n/a | Treprostinil | agonist | |
| 9 | Q9H244_CGE | CGE | DB00758 | 60606 | CHEMBL1771 | Clopidogrel | antagonist | IC50(nM) = 2400.0 |
| 10 | Q9H244_DB01240 | n/a | DB01240 | n/a | n/a | Epoprostenol | agonist | |
| 11 | Q9H244_DB05553 | n/a | DB05553 | n/a | n/a | Regrelor | antagonist | |
| 12 | Q9H244_DB06209 | n/a | DB06209 | n/a | n/a | Prasugrel | antagonist | |
| 13 | Q9H244_DB06350 | n/a | DB06350 | n/a | n/a | Elinogrel | antagonist | |
| 14 | Q9H244_DB06441 | n/a | DB06441 | n/a | n/a | Cangrelor | inhibitor | IC50(nM) = 0.398107 |
| 15 | Q9H244_TIQ | TIQ | DB08816 | 9871419 | CHEMBL398435 | Ticagrelor | inhibitor | Ki(nM) = 14.0 IC50(nM) = 5.0 |
| 16 | Q9H244_DB16349 | n/a | DB16349 | n/a | n/a | Vicagrel | antagonist |