Gene name: HRH4
Protein name: Histamine H4 receptor
List of molecules and drugs that interact with protein Q9H3N8
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9H3N8_CLR | CLR | DB04540 | 5997 | CHEMBL112570 | CHOLESTEROL | n/a | |
| 2 | Q9H3N8_HSM | HSM | DB05381 | 774 | CHEMBL90 | HISTAMINE | agonist | |
| 3 | Q9H3N8_ITF | ITF | n/a | 3692 | CHEMBL19439 | 2-(1~{H}-imidazol-5-yl)ethyl carbamimidothioate | n/a | |
| 4 | Q9H3N8_TP0 | TP0 | DB00321 | 2160 | CHEMBL629 | Amitriptyline | binder | Ki(nM) = 33.6 |
| 5 | Q9H3N8_DB00363 | n/a | DB00363 | n/a | n/a | Clozapine | agonist | Ki(nM) = 200.0 Kd(nM) = 11.9 |
| 6 | Q9H3N8_DB00408 | n/a | DB00408 | n/a | n/a | Loxapine | binder | Ki(nM) = 3981.0 |
| 7 | Q9H3N8_Z80 | Z80 | DB00477 | 2726 | CHEMBL71 | Chlorpromazine | binder | Ki(nM) = 50.2 |
| 8 | Q9H3N8_DB00543 | n/a | DB00543 | n/a | n/a | Amoxapine | binder | Ki(nM) = 5012.0 |
| 9 | Q9H3N8_DB01142 | no_lig_id | DB01142 | n/a | n/a | Doxepin | binder | |
| 10 | Q9H3N8_9SC | 9SC | DB01238 | 60795 | CHEMBL1112 | Aripiprazole | ligand | Ki(nM) = 10000.0 |
| 11 | Q9H3N8_DB01620 | n/a | DB01620 | n/a | n/a | Pheniramine | inverse agonist | Ki(nM) = 4184.0 |
| 12 | Q9H3N8_DB06148 | n/a | DB06148 | n/a | n/a | Mianserin | binder |