Gene name: SIRT5
Protein name: NAD-dependent protein deacylase
List of molecules and drugs that interact with protein Q9NXA8
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9NXA8_8VG | 8VG | n/a | 168477800 | n/a | 5-[[(5~{S})-6-[[(1~{S})-1-(4-hydroxyphenyl)-2-oxidanylidene-2-(prop-2-ynylamino)ethyl]amino]-6-oxidanylidene-5-[[4-[3-(trifluoromethyl)-1,2-diazirin-3-yl]phenyl]carbonylamino]hexyl]amino]-5-sulfanylidene-pentanoic acid | n/a | |
| 2 | Q9NXA8_APR | APR | n/a | 445794 | CHEMBL1231026 | ADENOSINE-5-DIPHOSPHORIBOSE | n/a | |
| 3 | Q9NXA8_BU2 | BU2 | DB02202 | 446973 | CHEMBL1231501 | 1,3-BUTANEDIOL | n/a | |
| 4 | Q9NXA8_BV8 | BV8 | n/a | 131750138 | n/a | 3-[[(~{Z})-~{C}-[(2~{R},3~{R},4~{S},5~{R})-5-[[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]sulfanyl-~{N}-[(5~{S})-6-[[(2~{S})-3-(1~{H}-indol-3-yl)-1-oxidanylidene-1-(propan-2-ylamino)propan-2-yl]amino]-6-oxidanylidene-5-(phenylmethoxycarbonylamino)hexyl]carbonimidoyl]amino]propanoic acid | n/a | |
| 5 | Q9NXA8_CGK | CGK | n/a | 137349093 | n/a | 3-[(2R,3aR,5R,6R,6aR)-5-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-2,6-dihydroxytetrahydrofuro[2,3-d][1,3]oxathiol-2-yl]propanoic acid | n/a | |
| 6 | Q9NXA8_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 7 | Q9NXA8_CNA | CNA | DB02498 | 163884 | CHEMBL5220997 | CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE | n/a | |
| 8 | Q9NXA8_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 9 | Q9NXA8_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 10 | Q9NXA8_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 11 | Q9NXA8_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 12 | Q9NXA8_GUA | GUA | DB03553 | 743;23322899; | CHEMBL1162495 | GLUTARIC ACID | n/a | |
| 13 | Q9NXA8_MCM | MCM | DB08168 | 92249 | CHEMBL270672 | 7-AMINO-4-METHYL-CHROMEN-2-ONE | n/a | |
| 14 | Q9NXA8_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 15 | Q9NXA8_NAD | NAD | DB14128 | 5892;5288979;10897651;73415790; | CHEMBL1234613 | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | n/a | |
| 16 | Q9NXA8_NHE | NHE | DB03309 | 66898;3852474; | n/a | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID | n/a | |
| 17 | Q9NXA8_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 18 | Q9NXA8_PHQ | PHQ | DB04569 | 10387 | CHEMBL1581748 | benzyl chlorocarbonate | n/a | |
| 19 | Q9NXA8_SLL | SLL | n/a | 46947876 | n/a | (2S)-2-azanyl-6-[(4-hydroxy-4-oxo-butanoyl)amino]hexanoic acid | n/a | |
| 20 | Q9NXA8_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 21 | Q9NXA8_STL | STL | DB02709 | 445154 | CHEMBL165 | RESVERATROL | n/a | |
| 22 | Q9NXA8_SVR | SVR | DB04786 | 5361;4261196;135973538; | CHEMBL265502 | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID | inhibitor | IC50(nM) = 2000.0 |
| 23 | Q9NXA8_AR6 | AR6 | DB02059 | 447048 | n/a | Adenosine-5-Diphosphoribose | n/a | |
| 24 | Q9NXA8_NCA | NCA | DB02701 | 936 | CHEMBL1140 | Nicotinamide | n/a | IC50(nM) = 28000.0 |
| 25 | Q9NXA8_OAD | OAD | DB03478 | 447049 | n/a | 2'-O-Acetyl Adenosine-5-Diphosphoribose | n/a | |
| 26 | Q9NXA8_DB15493 | n/a | DB15493 | n/a | n/a | Cambinol | inhibitor |