Gene name: MAP3K20
Protein name: Mitogen-activated protein kinase
List of molecules and drugs that interact with protein Q9NYL2
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9NYL2_032 | 032 | DB08881 | 42611257 | CHEMBL1229517 | N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | n/a | IC50(nM) = 4.0 |
| 2 | Q9NYL2_7Z0 | 7Z0 | n/a | 131953483 | CHEMBL4080860 | N-[2,4-bis(fluoranyl)-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]-3-bromanyl-benzenesulfonamide | n/a | |
| 3 | Q9NYL2_C9O | C9O | n/a | 138753620 | CHEMBL4542865 | ~{N}-[2,4-bis(fluoranyl)-3-[4-(3-methoxy-1~{H}-pyrazolo[3,4-b]pyridin-5-yl)-1,2,3-triazol-1-yl]phenyl]-3-bromanyl-benzenesulfonamide | n/a | |
| 4 | Q9NYL2_C9R | C9R | n/a | 146020550 | CHEMBL4468296 | ~{N}-[2,4-bis(fluoranyl)-3-[4-(3-methoxy-1~{H}-pyrazolo[3,4-b]pyridin-5-yl)-1,2,3-triazol-1-yl]phenyl]naphthalene-1-sulfonamide | n/a | |
| 5 | Q9NYL2_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 6 | Q9NYL2_IGS | IGS | n/a | 168451645 | n/a | ~{N}-[3-[[5-[1-[2,6-bis(fluoranyl)-3-[(3-phenylphenyl)sulfonylamino]phenyl]-1,2,3-triazol-4-yl]-1~{H}-pyrazolo[3,4-b]pyridin-3-yl]oxy]propyl]propanamide | n/a | |
| 7 | Q9NYL2_IGV | IGV | n/a | 168451646 | n/a | ~{N}-[2,4-bis(fluoranyl)-3-[4-[3-[(3~{S})-1-propanoylpyrrolidin-3-yl]oxy-1~{H}-pyrazolo[3,4-b]pyridin-5-yl]-1,2,3-triazol-1-yl]phenyl]-3-phenyl-benzenesulfonamide | n/a | |
| 8 | Q9NYL2_1N1 | 1N1 | DB01254 | 3062316 | CHEMBL1421 | Dasatinib | binder | Kd(nM) = 45.0 |
| 9 | Q9NYL2_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |