Gene name: CDK12
Protein name: Cyclin-dependent kinase 12
List of molecules and drugs that interact with protein Q9NYV4
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9NYV4_5I1 | 5I1 | n/a | 121486733 | n/a | N-[4-[(3R)-3-[[5-chloranyl-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamide | n/a | |
| 2 | Q9NYV4_8M1 | 8M1 | n/a | n/a | CHEMBL4159417 | N-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-N-{trans-4-[(quinazolin-2-yl)amino]cyclohexyl}acetamide | n/a | |
| 3 | Q9NYV4_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 4 | Q9NYV4_AF3 | AF3 | n/a | 2124;10129892; | n/a | ALUMINUM FLUORIDE | n/a | |
| 5 | Q9NYV4_ANP | ANP | n/a | 33113 | CHEMBL1230989 | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | n/a | |
| 6 | Q9NYV4_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | n/a | |
| 7 | Q9NYV4_CJM | CJM | n/a | 131953498 | CHEMBL4649135 | 2-[(2S)-1-(6-{[(4,5-difluoro-1H-benzimidazol-2-yl)methyl]amino}-9-ethyl-9H-purin-2-yl)piperidin-2-yl]ethan-1-ol | n/a | |
| 8 | Q9NYV4_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 9 | Q9NYV4_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 10 | Q9NYV4_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 11 | Q9NYV4_RC8 | RC8 | DB08463 | 10224714 | CHEMBL518800 | (2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol | n/a | |
| 12 | Q9NYV4_RKO | RKO | n/a | 684872 | n/a | 2-(1~{H}-benzimidazol-2-ylsulfanyl)-~{N}-(5-chloranylpyridin-2-yl)ethanamide | n/a | |
| 13 | Q9NYV4_RLC | RLC | n/a | 168477809 | n/a | (2~{R})-2-[[6-[(3-fluoranyl-4-pyridin-2-yl-phenyl)methylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | n/a | |
| 14 | Q9NYV4_RMF | RMF | n/a | 139600338 | CHEMBL4877117 | ~{N}-[[5,6-bis(chloranyl)-1~{H}-benzimidazol-2-yl]methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine | n/a | |
| 15 | Q9NYV4_RMX | RMX | n/a | 168477810 | n/a | 1,3-dimethyl-5-[[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)methylamino]purin-2-yl]amino]methyl]pyrazole-4-sulfonamide | n/a | |
| 16 | Q9NYV4_RNF | RNF | n/a | 10137573 | CHEMBL461557 | (2~{R})-2-[[6-[(4-phenylphenyl)methylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | n/a | |
| 17 | Q9NYV4_RNU | RNU | n/a | n/a | n/a | ~{N}-(5-methyl-2,3-dihydro-1,3-thiazol-2-yl)-3-(5-methylfuran-2-yl)carbonyl-1,3-thiazolidine-4-carboxamide | n/a | |
| 18 | Q9NYV4_RP9 | RP9 | n/a | 16426130 | CHEMBL4558806 | ~{N}-(5-bromanylpyridin-2-yl)-3-(4-oxidanylidenequinazolin-3-yl)propanamide | n/a | |
| 19 | Q9NYV4_RPW | RPW | n/a | 49677967 | CHEMBL5175040 | 2-[2-[(6-methylpyridin-2-yl)amino]-1,3-thiazol-4-yl]-~{N}-(5-methyl-1,3-thiazol-2-yl)ethanamide | n/a | |
| 20 | Q9NYV4_RQ5 | RQ5 | n/a | 168477812 | n/a | 2-[[6-[[4-(2-hydroxyethyloxy)phenyl]methylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | n/a | |
| 21 | Q9NYV4_RQ9 | RQ9 | n/a | 168477813 | n/a | (2~{R})-2-[[6-[[1-(3-chlorophenyl)pyrazol-3-yl]methylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | n/a | |
| 22 | Q9NYV4_RQE | RQE | n/a | 168477814 | n/a | ~{N}-(1~{H}-benzimidazol-2-ylmethyl)-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine | n/a | |
| 23 | Q9NYV4_RQL | RQL | n/a | 168477815 | n/a | (2~{R})-2-[[6-[[5,6-bis(chloranyl)-1~{H}-benzimidazol-2-yl]methylamino]-9-(1-methylpyrazol-4-yl)purin-2-yl]amino]butan-1-ol | n/a | |
| 24 | Q9NYV4_RQU | RQU | n/a | 168477816 | n/a | ~{N}-[2-(2-methoxyphenyl)ethyl]-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)methylamino]purin-2-yl]amino]ethanamide | n/a | |
| 25 | Q9NYV4_RR9 | RR9 | n/a | 168477817 | n/a | 6-[[[2-[[(2~{R})-1-oxidanylbutan-2-yl]amino]-9-propan-2-yl-purin-6-yl]amino]methyl]-3-pyridin-2-yl-1~{H}-pyridin-2-one | n/a | |
| 26 | Q9NYV4_RRC | RRC | DB06195 | 160355 | CHEMBL14762 | R-ROSCOVITINE | n/a | |
| 27 | Q9NYV4_RS5 | RS5 | n/a | 135473382 | CHEMBL258721 | 1-[2,6-bis(chloranyl)phenyl]-6-[[4-(2-hydroxyethyloxy)phenyl]methyl]-3-propan-2-yl-5H-pyrazolo[3,4-d]pyrimidin-4-one | n/a | |
| 28 | Q9NYV4_RSI | RSI | n/a | 168477818 | n/a | 2-morpholin-4-yl-9-propan-2-yl-~{N}-[(4-pyridin-2-ylphenyl)methyl]purin-6-amine | n/a | |
| 29 | Q9NYV4_RSU | RSU | n/a | 168477819 | n/a | (2~{R})-2-[[6-(3-phenylpropylamino)-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | n/a | |
| 30 | Q9NYV4_RUW | RUW | n/a | 168477820 | n/a | (2~{R})-2-[[6-(octylamino)-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | n/a | |
| 31 | Q9NYV4_RV6 | RV6 | n/a | 25053130 | CHEMBL518813 | (2~{R})-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)amino]purin-2-yl]amino]butan-1-ol | n/a | |
| 32 | Q9NYV4_RVH | RVH | n/a | 51819448 | n/a | (2~{R})-~{N}-(1~{H}-benzimidazol-2-yl)-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)propanamide | n/a | |
| 33 | Q9NYV4_RVQ | RVQ | n/a | 168477821 | n/a | ~{N}-[[5,6-bis(chloranyl)-1~{H}-benzimidazol-2-yl]methyl]-2-morpholin-4-yl-9-propan-2-yl-purin-6-amine | n/a | |
| 34 | Q9NYV4_RVU | RVU | n/a | 40633870 | n/a | ~{N}-(1~{H}-benzimidazol-2-yl)-1-(2-methoxy-5-methyl-phenyl)-5-oxidanylidene-pyrrolidine-3-carboxamide | n/a | |
| 35 | Q9NYV4_RW6 | RW6 | n/a | 18137974;135667559; | n/a | 2-(6,7-dihydro-4~{H}-thieno[3,2-c]pyridin-5-ylmethyl)-6,7-dimethoxy-3~{H}-quinazolin-4-one | n/a | |
| 36 | Q9NYV4_RWE | RWE | n/a | 168477822 | n/a | (2~{R})-2-[[6-(naphthalen-2-ylmethylamino)-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | n/a | |
| 37 | Q9NYV4_RWN | RWN | n/a | 168477823 | n/a | (2~{R})-2-[[6-[3-(3-methylphenyl)propylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | n/a | |
| 38 | Q9NYV4_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 39 | Q9NYV4_UUB | UUB | n/a | 168311441 | n/a | (E)-N-[4-[(1R,3R)-3-[[5-chloranyl-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]cyclohexyl]oxyphenyl]-4-(dimethylamino)but-2-enamide | n/a | |
| 40 | Q9NYV4_T6X | T6X | n/a | 168490156 | n/a | (2R)-2-[[6-(5-naphthalen-1-ylpentylamino)-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | n/a |